Collated Gene Ontology terms

Biological process: guanyl-nucleotide exchange factor activity(2012, 2013, 2021, 2022, 2025) small GTPase binding(2002, 2022, 2025)

Molecular function: retrograde transport, endosome to Golgi2014, 2022, 2025 positive regulation of triglyceride transport2019, 2025 negative regulation of neuron projection development2017, 2025 regulation of Rab protein signal transduction2013 early stripe melanocyte differentiation2023

Cellular component: membrane2025 trans-Golgi network2014, 2022, 2025 cytosol2016, 2025 retromer complex2014, 2025 Golgi apparatus2009, 2013, 2025 Golgi membrane2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A1L1RT22_CHICK
Ensembl»
1.5
DENND5A DENN domain containing 5A Gallus gallus
TI:9031 None
   
A0A3Q2UHC2_CHICK
Ensembl»
1.0
DENND5B DENN domain containing 5B Gallus gallus
TI:9031 None
   
A0A8I5ZYN4_RAT
RGD»
2.0
Dennd5b DENN domain containing 5B Rattus norvegicus
TI:10116 None
   
A0A8M3B1L1_DANRE
ZFIN»
2.3
dennd5a DENN domain-containing protein 5A isoform X1 Danio rerio
TI:7955 None
   
DEN5A_HUMAN
Ensembl»
4.5
DENND5A DENN domain-containing protein 5A
(Rab6-interacting protein 1) (Rab6IP1)		 Homo sapiens
TI:9606 None
 
DEN5A_MOUSE
Ensembl»
4.8
Dennd5a DENN domain-containing protein 5A
(Rab6-interacting protein 1) (Rab6IP1)		 Mus musculus
TI:10090 None
 
DEN5A_RAT
RGD»
3.8
Dennd5a DENN domain-containing protein 5A
(Rab6-interacting protein 1) (Rab6IP1)		 Rattus norvegicus
TI:10116 None
 
DEN5B_DANRE
ZFIN»
1.5
dennd5b DENN domain-containing protein
5B (Rab6IP1-like protein)		 Danio rerio
TI:7955 None
 
DEN5B_HUMAN
Ensembl»
2.7
DENND5B DENN domain-containing protein
5B (Rab6IP1-like protein)		 Homo sapiens
TI:9606 None
 
DEN5B_MOUSE
Ensembl»
2.8
Dennd5b DENN domain-containing protein
5B (Rab6IP1-like protein)		 Mus musculus
TI:10090 None
 
Q18780_CAEEL
WormBase»
1.0
lst-6 Lateral Signaling Target Caenorhabditis elegans
TI:6239 None
 
Q9W0E1_DROME
FlyBase»
2.0
pns Pinstripe, isoform A (Pinstripe, isoform B) Drosophila melanogaster
TI:7227 None