Collated Gene Ontology terms

Biological process: guanyl-nucleotide exchange factor activity(2012, 2013, 2021, 2022, 2024) small GTPase binding(2002, 2022, 2024)

Molecular function: retrograde transport, endosome to Golgi2014, 2022, 2024 positive regulation of triglyceride transport2019, 2024 negative regulation of neuron projection development2017, 2024 regulation of Rab protein signal transduction2013

Cellular component: membrane2024 trans-Golgi network2014, 2022, 2024 cytosol2016, 2024 Golgi apparatus2009, 2013, 2024 retromer complex2014, 2024 Golgi membrane2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
DEN5B_HUMAN
Ensembl»
2.7
DENND5B DENN domain-containing protein
5B (Rab6IP1-like protein)		 Homo sapiens
TI:9606 None
 
DEN5A_HUMAN
Ensembl»
4.5
DENND5A DENN domain-containing protein 5A
(Rab6-interacting protein 1) (Rab6IP1)		 Homo sapiens
TI:9606 None
 
DEN5B_MOUSE
Ensembl»
1.3
Dennd5b DENN domain-containing protein
5B (Rab6IP1-like protein)		 Mus musculus
TI:10090 None
 
DEN5A_MOUSE
Ensembl»
1.8
Dennd5a DENN domain-containing protein 5A
(Rab6-interacting protein 1) (Rab6IP1)		 Mus musculus
TI:10090 None
 
DEN5A_RAT
RGD»
3.8
Dennd5a DENN domain-containing protein 5A
(Rab6-interacting protein 1) (Rab6IP1)		 Rattus norvegicus
TI:10116 None
 
DEN5B_DANRE
ZFIN»
1.5
dennd5b DENN domain-containing protein
5B (Rab6IP1-like protein)		 Danio rerio
TI:7955 None
 
Q9W0E1_DROME
FlyBase»
2.0
pns Pinstripe, isoform A (Pinstripe, isoform B) Drosophila melanogaster
TI:7227 None
 
Q18780_CAEEL
WormBase»
1.0
lst-6 Lateral Signaling Target Caenorhabditis elegans
TI:6239 None
 
A0A1L1RT22_CHICK
Ensembl»
0.0
DENND5A DENN domain containing 5A Gallus gallus
TI:9031 None
   
A0A3Q2UHC2_CHICK
Ensembl»
1.0
DENND5B DENN domain containing 5B Gallus gallus
TI:9031 None
   
A0A8I5ZYN4_RAT
RGD»
1.0
Dennd5b DENN domain containing 5B Rattus norvegicus
TI:10116 None
   
A0A8M3B1L1_DANRE
CTD»
1.5
dennd5a DENN domain-containing protein 5A isoform X1 Danio rerio
TI:7955 None