Cluster UKP07525
- PINSTRIPE, ISOFORM A
Standard knownness: 4.5; Custom knownness: None; Num. species: 34; Orthology database: Panther19.0; Protein members: 57
Collated Gene Ontology terms
Biological process:
guanyl-nucleotide exchange factor activity(2012, 2013, 2021, 2022, 2024)
small GTPase binding(2002, 2022, 2024)
Molecular function: retrograde transport, endosome to Golgi2014, 2022, 2024 positive regulation of triglyceride transport2019, 2024 negative regulation of neuron projection development2017, 2024 regulation of Rab protein signal transduction2013
Cellular component: membrane2024 trans-Golgi network2014, 2022, 2024 cytosol2016, 2024 Golgi apparatus2009, 2013, 2024 retromer complex2014, 2024 Golgi membrane2024
Phylogenetic distribution
| Chordates: | 22/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 4/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 1/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 0/3 | |
| Excavates: | 0/4 | |
| Harosa: | 0/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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G1KJ69_ANOCA Ensembl» |
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DENND5A | DENN domain containing 5A |
Anolis carolinensis TI:28377 None |
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G1KMX4_ANOCA Ensembl» |
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DENND5B | DENN domain containing 5B |
Anolis carolinensis TI:28377 None |
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A0A1S4H7A9_ANOGA EnsemblMetazoa» |
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Uncharacterized protein |
Anopheles gambiae TI:7165 None |
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F1MQ87_BOVIN Ensembl» |
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DENND5B | DENN domain containing 5B |
Bos taurus TI:9913 None |
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A0A9J7HRH9_BRAFL CTD» |
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LOC118406634 | DENN domain-containing protein 5B-like isoform X1 |
Branchiostoma floridae TI:7739 None |
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A8XCP9_CAEBR WormBase» |
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lst-6 | Protein CBG11204 |
Caenorhabditis briggsae TI:6238 None |
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Q18780_CAEEL WormBase» |
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lst-6 | Lateral Signaling Target |
Caenorhabditis elegans TI:6239 None |
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A0A8I3NMA6_CANLF Ensembl» |
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DENND5A | DENN domain containing 5A |
Canis lupus TI:9612 None |
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A0A8I3NWZ3_CANLF Ensembl» |
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DENND5B | DENN domain containing 5B |
Canis lupus TI:9612 None |
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F6SBQ3_CIOIN Ensembl» |
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UDENN domain-containing protein |
Ciona intestinalis TI:7719 None |
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F7AE11_CIOIN Ensembl» |
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RUN domain-containing protein |
Ciona intestinalis TI:7719 None |
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A0A8M3B1L1_DANRE CTD» |
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dennd5a | DENN domain-containing protein 5A isoform X1 |
Danio rerio TI:7955 None |
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DEN5B_DANRE ZFIN» |
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dennd5b | DENN domain-containing protein 5B (Rab6IP1-like protein) |
Danio rerio TI:7955 None |
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E9FRQ9_DAPPU EnsemblMetazoa» |
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DAPPUDRAFT_219947 | RUN domain-containing protein |
Daphnia pulex TI:6669 None |
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Q9W0E1_DROME FlyBase» |
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pns | Pinstripe, isoform A (Pinstripe, isoform B) |
Drosophila melanogaster TI:7227 None |
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A0A5F5PE93_HORSE Ensembl» |
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DENND5A | DENN domain containing 5A |
Equus caballus TI:9796 None |
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A0A5F5XKZ0_FELCA Ensembl» |
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DENND5A | DENN domain containing 5A |
Felis catus TI:9685 None |
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M3W481_FELCA Ensembl» |
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DENND5B | DENN domain containing 5B |
Felis catus TI:9685 None |
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A0A1L1RT22_CHICK Ensembl» |
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DENND5A | DENN domain containing 5A |
Gallus gallus TI:9031 None |
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A0A3Q2UHC2_CHICK Ensembl» |
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DENND5B | DENN domain containing 5B |
Gallus gallus TI:9031 None |
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G3R4D5_GORGO Ensembl» |
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DENND5A | DENN domain containing 5A |
Gorilla gorilla TI:9593 None |
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G3RGD9_GORGO Ensembl» |
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DENN domain containing 5B |
Gorilla gorilla TI:9593 None |
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T1EEM9_HELRO EnsemblMetazoa» |
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20195031 | UDENN domain-containing protein |
Helobdella robusta TI:6412 None |
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DEN5A_HUMAN Ensembl» |
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DENND5A | DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1) |
Homo sapiens TI:9606 None |
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DEN5B_HUMAN Ensembl» |
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DENND5B | DENN domain-containing protein 5B (Rab6IP1-like protein) |
Homo sapiens TI:9606 None |
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W5M775_LEPOC Ensembl» |
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DENN/MADD domain containing 5A |
Lepisosteus oculatus TI:7918 None |
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W5ND71_LEPOC Ensembl» |
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DENN/MADD domain containing 5B |
Lepisosteus oculatus TI:7918 None |
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A0A5F8A6B2_MACMU Ensembl» |
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DENND5B | DENN domain containing 5B |
Macaca mulatta TI:9544 None |
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F7HB53_MACMU Ensembl» |
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DENND5A | DENN domain containing 5A |
Macaca mulatta TI:9544 None |
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F6W2Y5_MONDO Ensembl» |
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DENND5B | DENN domain containing 5B |
Monodelphis domestica TI:13616 None |
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F7A8J4_MONDO Ensembl» |
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DENND5A | DENN domain containing 5A |
Monodelphis domestica TI:13616 None |
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A9UQR3_MONBE EnsemblProtists» |
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MONBRDRAFT_22491 | UDENN domain-containing protein |
Monosiga brevicollis TI:81824 None |
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DEN5A_MOUSE Ensembl» |
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Dennd5a | DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1) |
Mus musculus TI:10090 None |
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DEN5B_MOUSE Ensembl» |
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Dennd5b | DENN domain-containing protein 5B (Rab6IP1-like protein) |
Mus musculus TI:10090 None |
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A7SZQ4_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g139391 | UDENN domain-containing protein |
Nematostella vectensis TI:45351 None |
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A0A6I8NK98_ORNAN Ensembl» |
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DENND5B | DENN domain containing 5B |
Ornithorhynchus anatinus TI:9258 None |
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A0A6I8PJ14_ORNAN Ensembl» |
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DENND5A | DENN domain containing 5A |
Ornithorhynchus anatinus TI:9258 None |
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A0A3B3H841_ORYLA Ensembl» |
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LOC101172731 | DENN domain-containing protein 5B-like |
Oryzias latipes TI:8090 None |
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A0A3B3HHA5_ORYLA Ensembl» |
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dennd5a | DENN domain containing 5A |
Oryzias latipes TI:8090 None |
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H2Q358_PANTR Ensembl» |
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DENND5B | DENN domain containing 5B |
Pan troglodytes TI:9598 None |
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H2Q359_PANTR Ensembl» |
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DENND5A | DENN domain containing 5A (DENN/MADD domain containing 5A) |
Pan troglodytes TI:9598 None |
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A0A8R1UE43_PRIPA EnsemblMetazoa» |
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WBGene00112389 | Uncharacterized protein |
Pristionchus pacificus TI:54126 None |
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A0A8I5ZYN4_RAT RGD» |
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Dennd5b | DENN domain containing 5B |
Rattus norvegicus TI:10116 None |
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DEN5A_RAT RGD» |
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Dennd5a | DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1) |
Rattus norvegicus TI:10116 None |
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A0A7M7P0T2_STRPU EnsemblMetazoa» |
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DENN domain-containing protein 5B |
Strongylocentrotus purpuratus TI:7668 None |
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A0A287ANX8_PIG Ensembl» |
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DENND5A | DENN domain containing 5A |
Sus scrofa TI:9823 None |
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A0A480JZJ1_PIG Ensembl» |
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DENND5B | DENN domain containing 5B (DENN domain-containing protein 5B isoform 1) (DENN domain-containing protein 5B isoform X1) |
Sus scrofa TI:9823 None |
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D2A1W8_TRICA EnsemblMetazoa» |
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AUGUSTUS-3.0.2_07707 | DENN domain-containing protein 5B-like Protein |
Tribolium castaneum TI:7070 None |
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B3SC33_TRIAD EnsemblMetazoa» |
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TRIADDRAFT_61833 | UDENN domain-containing protein |
Trichoplax adhaerens TI:10228 None |
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A0A1L8GDV9_XENLA Xenbase» |
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dennd5a.S | DENN domain-containing protein 5A isoform X1 |
Xenopus laevis TI:8355 None |
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A0A1L8GW72_XENLA Xenbase» |
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dennd5b.L | DENN domain-containing protein 5B isoform X3 |
Xenopus laevis TI:8355 None |
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A0A6I8RIJ9_XENTR Xenbase» |
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dennd5b | DENN domain-containing protein 5B isoform X1 (DENN/MADD domain containing 5B) |
Xenopus tropicalis TI:8364 None |
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A0A8J1KL52_XENLA Xenbase» |
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LOC108715298 | DENN domain-containing protein 5A isoform X3 |
Xenopus laevis TI:8355 None |
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A0A8J1MK68_XENLA Xenbase» |
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LOC108710730 | DENN domain-containing protein 5B isoform X1 |
Xenopus laevis TI:8355 None |
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A0A8J1MQU4_XENLA Xenbase» |
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LOC108712539 | DENN domain-containing protein 5B-like isoform X1 |
Xenopus laevis TI:8355 None |
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A0A8J1MUU7_XENLA Xenbase» |
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LOC108713446 | DENN domain-containing protein 5A isoform X1 |
Xenopus laevis TI:8355 None |
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B2GUD7_XENTR Xenbase» |
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dennd5a | DENN domain-containing protein 5A (LOC100158564 protein) |
Xenopus tropicalis TI:8364 None |
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