Collated Gene Ontology terms

Biological process: guanyl-nucleotide exchange factor activity(2012, 2013, 2021, 2022, 2023) small GTPase binding(2002, 2022, 2023)

Molecular function: retrograde transport, endosome to Golgi2014, 2022, 2023 positive regulation of triglyceride transport2019, 2023 negative regulation of neuron projection development2017, 2023 regulation of Rab protein signal transduction2013

Cellular component: membrane2023 trans-Golgi network2014, 2022, 2023 cytosol2016, 2023 Golgi apparatus2009, 2013, 2023 retromer complex2014, 2023 Golgi membrane2023

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»
Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
G1KJ69_ANOCA
Ensembl»
0.0
DENND5A DENN domain containing 5A Anolis carolinensis
TI:28377 None
   
G1KMX4_ANOCA
Ensembl»
0.0
DENND5B DENN domain containing 5B Anolis carolinensis
TI:28377 None
   
A0A1S4H7A9_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
A0A3Q1MUN3_BOVIN
Ensembl»
0.0
DENND5A DENN domain containing 5A Bos taurus
TI:9913 None
   
F1MQ87_BOVIN
Ensembl»
0.0
DENND5B DENN domain containing 5B Bos taurus
TI:9913 None
   
A0A9J7HRH9_BRAFL
CTD»
0.0
LOC118406634 DENN domain-containing protein
5B-like isoform X1
Branchiostoma floridae
TI:7739 None
   
A8XCP9_CAEBR
WormBase»
0.0
lst-6 Protein CBG11204 Caenorhabditis briggsae
TI:6238 None
 
Q18780_CAEEL
WormBase»
1.0
lst-6 Lateral Signaling Target Caenorhabditis elegans
TI:6239 None
 
A0A8I3NMA6_CANLF
Ensembl»
0.0
DENND5A DENN domain containing 5A Canis lupus
TI:9612 None
   
A0A8I3S0N9_CANLF
Ensembl»
0.0
DENND5B DENN domain containing 5B Canis lupus
TI:9612 None
   
F6SBQ3_CIOIN
Ensembl»
0.0
UDENN domain-containing protein Ciona intestinalis
TI:7719 None
   
F7AE11_CIOIN
Ensembl»
0.0
RUN domain-containing protein Ciona intestinalis
TI:7719 None
   
A0A8M3B1L1_DANRE
CTD»
0.0
dennd5a DENN domain-containing protein 5A isoform X1 Danio rerio
TI:7955 None
   
DEN5B_DANRE
ZFIN»
1.5
dennd5b DENN domain-containing protein
5B (Rab6IP1-like protein)
Danio rerio
TI:7955 None
 
E9FRQ9_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_219947 RUN domain-containing protein Daphnia pulex
TI:6669 None
 
Q9W0E1_DROME
FlyBase»
2.0
pns Pinstripe, isoform A (Pinstripe, isoform B) Drosophila melanogaster
TI:7227 None
 
A0A3Q2HA02_HORSE
Ensembl»
0.0
DENND5B DENN domain containing 5B Equus caballus
TI:9796 None
   
A0A5F5PE93_HORSE
Ensembl»
0.0
DENND5A DENN domain containing 5A Equus caballus
TI:9796 None
   
A0A5F5XKZ0_FELCA
Ensembl»
0.0
DENND5A DENN domain containing 5A Felis catus
TI:9685 None
 
M3W481_FELCA
Ensembl»
0.0
DENND5B DENN domain containing 5B Felis catus
TI:9685 None
 
A0A1L1RT22_CHICK
Ensembl»
0.0
DENND5A DENN domain containing 5A Gallus gallus
TI:9031 None
   
A0A3Q2UHC2_CHICK
Ensembl»
1.0
DENND5B DENN domain containing 5B Gallus gallus
TI:9031 None
   
G3R4D5_GORGO
Ensembl»
0.0
DENND5A DENN domain containing 5A Gorilla gorilla
TI:9593 None
 
G3RGD9_GORGO
Ensembl»
0.0
DENN domain containing 5B Gorilla gorilla
TI:9593 None
 
T1EEM9_HELRO
EnsemblMetazoa»
0.0
20195031 UDENN domain-containing protein Helobdella robusta
TI:6412 None
 
DEN5A_HUMAN
Ensembl»
4.5
DENND5A DENN domain-containing protein 5A
(Rab6-interacting protein 1) (Rab6IP1)
Homo sapiens
TI:9606 None
 
DEN5B_HUMAN
Ensembl»
2.7
DENND5B DENN domain-containing protein
5B (Rab6IP1-like protein)
Homo sapiens
TI:9606 None
 
W5M775_LEPOC
Ensembl»
0.0
DENN/MADD domain containing 5A Lepisosteus oculatus
TI:7918 None
 
W5ND71_LEPOC
Ensembl»
0.0
DENN/MADD domain containing 5B Lepisosteus oculatus
TI:7918 None
 
F7DNY8_MACMU
Ensembl»
0.0
DENND5B DENN domain containing 5B Macaca mulatta
TI:9544 None
   
F7HB53_MACMU
Ensembl»
0.0
DENND5A DENN domain containing 5A Macaca mulatta
TI:9544 None
   
F6W2Y5_MONDO
Ensembl»
0.0
DENND5B DENN domain containing 5B Monodelphis domestica
TI:13616 None
   
F7A8J4_MONDO
Ensembl»
0.0
DENND5A DENN domain containing 5A Monodelphis domestica
TI:13616 None
   
A9UQR3_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_22491 UDENN domain-containing protein Monosiga brevicollis
TI:81824 None
 
DEN5A_MOUSE
Ensembl»
4.8
Dennd5a DENN domain-containing protein 5A
(Rab6-interacting protein 1) (Rab6IP1)
Mus musculus
TI:10090 None
 
DEN5B_MOUSE
Ensembl»
2.8
Dennd5b DENN domain-containing protein
5B (Rab6IP1-like protein)
Mus musculus
TI:10090 None
 
A7SZQ4_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g139391 UDENN domain-containing protein Nematostella vectensis
TI:45351 None
 
A0A6I8NK98_ORNAN
Ensembl»
0.0
DENND5B DENN domain containing 5B Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8PJ14_ORNAN
Ensembl»
0.0
DENND5A DENN domain containing 5A Ornithorhynchus anatinus
TI:9258 None
   
A0A3B3H841_ORYLA
Ensembl»
0.0
LOC101172731 DENN domain-containing protein 5B-like Oryzias latipes
TI:8090 None
   
A0A3B3HHA5_ORYLA
Ensembl»
0.0
dennd5a DENN domain containing 5A Oryzias latipes
TI:8090 None
   
H2Q359_PANTR
Ensembl»
0.0
DENND5A DENN domain containing 5A
(DENN/MADD domain containing 5A)
Pan troglodytes
TI:9598 None
 
K7B3J6_PANTR
Ensembl»
0.0
DENND5B DENN domain containing 5B
(DENN/MADD domain containing 5B)
Pan troglodytes
TI:9598 None
 
A0A8R1UE43_PRIPA
EnsemblMetazoa»
0.0
WBGene00112389 Uncharacterized protein Pristionchus pacificus
TI:54126 None
   
A0A8I5ZYN4_RAT
RGD»
1.0
Dennd5b DENN domain containing 5B Rattus norvegicus
TI:10116 None
   
DEN5A_RAT
RGD»
3.8
Dennd5a DENN domain-containing protein 5A
(Rab6-interacting protein 1) (Rab6IP1)
Rattus norvegicus
TI:10116 None
 
A0A7M7P0T2_STRPU
EnsemblMetazoa»
0.0
DENN domain-containing protein 5B Strongylocentrotus purpuratus
TI:7668 None
   
A0A480JZJ1_PIG
Ensembl»
0.0
DENND5B DENN domain containing 5B (DENN domain-containing protein 5B
isoform 1) (DENN domain-containing protein 5B isoform X1)
Sus scrofa
TI:9823 None
 
A0A8W4F7P0_PIG
Ensembl»
0.0
DENND5A DENN domain containing 5A Sus scrofa
TI:9823 None
   
D2A1W8_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_07707 DENN domain-containing protein 5B-like Protein Tribolium castaneum
TI:7070 None
 
B3SC33_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_61833 UDENN domain-containing protein Trichoplax adhaerens
TI:10228 None
 
A0A6I8RIJ9_XENTR
Xenbase»
0.0
dennd5b DENN domain-containing protein 5B isoform
X1 (DENN/MADD domain containing 5B)
Xenopus tropicalis
TI:8364 None
   
B2GUD7_XENTR
Xenbase»
0.0
dennd5a DENN domain-containing protein
5A (LOC100158564 protein)
Xenopus tropicalis
TI:8364 None