Cluster UKP07525
- PINSTRIPE, ISOFORM A
Standard knownness: 4.8; Custom knownness: None; Num. species: 34; Orthology database: Panther19.0; Protein members: 59
Collated Gene Ontology terms
Biological process:
guanyl-nucleotide exchange factor activity(2012, 2013, 2021, 2022, 2025)
small GTPase binding(2002, 2022, 2025)
Molecular function: retrograde transport, endosome to Golgi2014, 2022, 2025 positive regulation of triglyceride transport2019, 2025 negative regulation of neuron projection development2017, 2025 regulation of Rab protein signal transduction2013 early stripe melanocyte differentiation2023
Cellular component: membrane2025 trans-Golgi network2014, 2022, 2025 cytosol2016, 2025 retromer complex2014, 2025 Golgi apparatus2009, 2013, 2025 Golgi membrane2025
Phylogenetic distribution
| Chordates: | 22/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 4/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 1/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 0/3 | |
| Excavates: | 0/4 | |
| Harosa: | 0/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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DEN5B_HUMAN Ensembl» |
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DENND5B | DENN domain-containing protein 5B (Rab6IP1-like protein) |
Homo sapiens TI:9606 None |
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W5ND71_LEPOC Ensembl» |
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DENN/MADD domain containing 5B |
Lepisosteus oculatus TI:7918 None |
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DEN5A_HUMAN Ensembl» |
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DENND5A | DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1) |
Homo sapiens TI:9606 None |
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A0A480JZJ1_PIG Ensembl» |
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DENND5B | DENN domain containing 5B (DENN domain-containing protein 5B isoform 1) (DENN domain-containing protein 5B isoform X1) |
Sus scrofa TI:9823 None |
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G3R4D5_GORGO Ensembl» |
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DENND5A | DENN domain containing 5A |
Gorilla gorilla TI:9593 None |
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DEN5B_MOUSE Ensembl» |
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Dennd5b | DENN domain-containing protein 5B (Rab6IP1-like protein) |
Mus musculus TI:10090 None |
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DEN5A_MOUSE Ensembl» |
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Dennd5a | DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1) |
Mus musculus TI:10090 None |
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H2Q358_PANTR Ensembl» |
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DENND5B | DENN domain containing 5B |
Pan troglodytes TI:9598 None |
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H2Q359_PANTR Ensembl» |
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DENND5A | DENN domain containing 5A (DENN/MADD domain containing 5A) |
Pan troglodytes TI:9598 None |
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DEN5A_RAT RGD» |
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Dennd5a | DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1) |
Rattus norvegicus TI:10116 None |
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G3RGD9_GORGO Ensembl» |
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DENND5B | DENN domain containing 5B |
Gorilla gorilla TI:9593 None |
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W5M775_LEPOC Ensembl» |
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DENN domain containing 5A |
Lepisosteus oculatus TI:7918 None |
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DEN5B_DANRE ZFIN» |
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dennd5b | DENN domain-containing protein 5B (Rab6IP1-like protein) |
Danio rerio TI:7955 None |
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Q9W0E1_DROME FlyBase» |
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pns | Pinstripe, isoform A (Pinstripe, isoform B) |
Drosophila melanogaster TI:7227 None |
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T1EEM9_HELRO EnsemblMetazoa» |
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20195031 | UDENN domain-containing protein |
Helobdella robusta TI:6412 None |
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A0A1S4H7A9_ANOGA EnsemblMetazoa» |
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Uncharacterized protein |
Anopheles gambiae TI:7165 None |
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A7SZQ4_NEMVE euHCVdb» |
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NEMVEDRAFT_v1g139391 | UDENN domain-containing protein |
Nematostella vectensis TI:45351 None |
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A8XCP9_CAEBR WormBase» |
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lst-6 | Protein CBG11204 |
Caenorhabditis briggsae TI:6238 None |
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A9UQR3_MONBE neXtProt» |
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MONBRDRAFT_22491 | UDENN domain-containing protein |
Monosiga brevicollis TI:81824 None |
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B2GUD7_XENTR Xenbase» |
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dennd5a | DENN domain-containing protein 5A (LOC100158564 protein) |
Xenopus tropicalis TI:8364 None |
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B3SC33_TRIAD CTD» |
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TRIADDRAFT_61833 | UDENN domain-containing protein |
Trichoplax adhaerens TI:10228 None |
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D2A1W8_TRICA neXtProt» |
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AUGUSTUS-3.0.2_07707 | DENN domain-containing protein 5B-like Protein |
Tribolium castaneum TI:7070 None |
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E9FRQ9_DAPPU euHCVdb» |
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DAPPUDRAFT_219947 | RUN domain-containing protein |
Daphnia pulex TI:6669 None |
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Q18780_CAEEL WormBase» |
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lst-6 | Lateral Signaling Target |
Caenorhabditis elegans TI:6239 None |
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A0A1L1RT22_CHICK Ensembl» |
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DENND5A | DENN domain containing 5A |
Gallus gallus TI:9031 None |
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A0A1L8GDV9_XENLA Xenbase» |
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dennd5a.S | DENN domain-containing protein 5A isoform X1 |
Xenopus laevis TI:8355 None |
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A0A1L8GW72_XENLA Xenbase» |
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dennd5b.L | DENN domain-containing protein 5B isoform X3 |
Xenopus laevis TI:8355 None |
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A0A287ANX8_PIG Ensembl» |
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DENND5A | DENN domain containing 5A |
Sus scrofa TI:9823 None |
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A0A3B3H841_ORYLA Ensembl» |
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LOC101172731 | DENN domain containing 5B |
Oryzias latipes TI:8090 None |
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A0A3B3HHA5_ORYLA Ensembl» |
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DENND5A | DENN domain containing 5A |
Oryzias latipes TI:8090 None |
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A0A3Q2UHC2_CHICK Ensembl» |
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DENND5B | DENN domain containing 5B |
Gallus gallus TI:9031 None |
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A0A5F5PE93_HORSE Ensembl» |
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DENND5A | DENN domain containing 5A |
Equus caballus TI:9796 None |
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A0A5F8A4T1_MACMU Ensembl» |
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DENND5A | DENN domain containing 5A |
Macaca mulatta TI:9544 None |
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A0A5F8A6B2_MACMU Ensembl» |
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DENND5B | DENN domain containing 5B |
Macaca mulatta TI:9544 None |
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A0A6I8NK98_ORNAN Ensembl» |
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DENND5B | DENN domain containing 5B |
Ornithorhynchus anatinus TI:9258 None |
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A0A6I8PJ14_ORNAN Ensembl» |
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DENND5A | DENN domain containing 5A |
Ornithorhynchus anatinus TI:9258 None |
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A0A6I8RIJ9_XENTR Xenbase» |
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dennd5b | DENN domain-containing protein 5B isoform X1 (DENN/MADD domain containing 5B) |
Xenopus tropicalis TI:8364 None |
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A0A7M7P0T2_STRPU EnsemblMetazoa» |
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DENN domain-containing protein 5B |
Strongylocentrotus purpuratus TI:7668 None |
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A0A8I3NMA6_CANLF Ensembl» |
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DENND5A | DENN domain containing 5A |
Canis lupus TI:9612 None |
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A0A8I3NWZ3_CANLF Ensembl» |
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DENND5B | DENN domain containing 5B |
Canis lupus TI:9612 None |
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A0A8I5ZYN4_RAT RGD» |
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Dennd5b | DENN domain containing 5B |
Rattus norvegicus TI:10116 None |
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A0A8J1KL52_XENLA CTD» |
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LOC108715298 | DENN domain-containing protein 5A isoform X3 |
Xenopus laevis TI:8355 None |
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A0A8J1MK68_XENLA CTD» |
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LOC108710730 | DENN domain-containing protein 5B isoform X1 |
Xenopus laevis TI:8355 None |
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A0A8J1MQU4_XENLA CTD» |
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LOC108712539 | DENN domain-containing protein 5B-like isoform X1 |
Xenopus laevis TI:8355 None |
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A0A8J1MUU7_XENLA CTD» |
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LOC108713446 | DENN domain-containing protein 5A isoform X1 |
Xenopus laevis TI:8355 None |
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A0A8M3B1L1_DANRE ZFIN» |
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dennd5a | DENN domain-containing protein 5A isoform X1 |
Danio rerio TI:7955 None |
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A0A8R1UE43_PRIPA EnsemblMetazoa» |
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WBGene00112389 | Uncharacterized protein |
Pristionchus pacificus TI:54126 None |
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A0A9J7HRH9_BRAFL neXtProt» |
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LOC118406634 | DENN domain-containing protein 5B-like isoform X1 |
Branchiostoma floridae TI:7739 None |
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A0A9L0SUN0_HORSE Ensembl» |
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DENND5B | DENN domain containing 5B |
Equus caballus TI:9796 None |
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A0AAA9SAM7_BOVIN Ensembl» |
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DENND5A | DENN domain containing 5A |
Bos taurus TI:9913 None |
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A0ABI7XHF1_FELCA Ensembl» |
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DENND5A | DENN domain containing 5A |
Felis catus TI:9685 None |
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A0ABI7ZHJ8_FELCA Ensembl» |
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DENND5B | DENN domain containing 5B |
Felis catus TI:9685 None |
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F1MQ87_BOVIN Ensembl» |
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DENND5B | DENN domain containing 5B |
Bos taurus TI:9913 None |
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F6SBQ3_CIOIN Ensembl» |
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UDENN domain-containing protein |
Ciona intestinalis TI:7719 None |
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F6W2Y5_MONDO Ensembl» |
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DENND5B | DENN domain containing 5B |
Monodelphis domestica TI:13616 None |
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F7A8J4_MONDO Ensembl» |
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DENND5A | DENN domain containing 5A |
Monodelphis domestica TI:13616 None |
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F7AE11_CIOIN Ensembl» |
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RUN domain-containing protein |
Ciona intestinalis TI:7719 None |
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G1KJ69_ANOCA Ensembl» |
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DENND5A | DENN domain containing 5A |
Anolis carolinensis TI:28377 None |
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G1KMX4_ANOCA Ensembl» |
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DENND5B | DENN domain containing 5B |
Anolis carolinensis TI:28377 None |
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