Collated Gene Ontology terms

Biological process: small GTPase binding(2022, 2025) signaling adaptor activity(2019, 2025) actin binding(2025) GTPase inhibitor activity(2003)

Molecular function: regulation of Rho protein signal transduction2011, 2025 regulation of cell shape2006, 2025 phagocytosis2025 regulation of signal transduction2008, 2025 actin filament organization2025 small GTPase-mediated signal transduction2006 signal transduction2003 regulation of actin filament polymerization2022 negative regulation of JNK cascade2006 midbrain-hindbrain boundary morphogenesis2013

Cellular component: plasma membrane2003, 2008, 2017, 2025 cytoskeleton2025 phagocytic cup2025 cell junction2025 nucleus2025 cytoplasm2022 cell cortex2006

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
C42S2_MOUSE
Ensembl»
1.5
Cdc42se2 CDC42 small effector protein 2 Mus musculus
TI:10090 None
 
C42S2_RAT
RGD»
1.5
Cdc42se2 CDC42 small effector protein 2 Rattus norvegicus
TI:10116 None
 
C42S1_MOUSE
Ensembl»
1.5
Cdc42se1 CDC42 small effector protein 1 Mus musculus
TI:10090 None
 
C42S1_HUMAN
Ensembl»
1.8
CDC42SE1 CDC42 small effector protein 1 (CDC42-binding protein
SCIP1) (Small effector of CDC42 protein 1)		 Homo sapiens
TI:9606 None
 
C42S2_HUMAN
Ensembl»
1.6
CDC42SE2 CDC42 small effector protein 2
(Small effector of CDC42 protein 2)		 Homo sapiens
TI:9606 None
 
C42ES_DROME
FlyBase»
1.5
Spec2 CDC42 small effector protein homolog (Dspec) Drosophila melanogaster
TI:7227 None
 
C42S1_RAT
RGD»
0.0
Cdc42se1 CDC42 small effector protein 1 Rattus norvegicus
TI:10116 None
 
C42S2_DANRE
ZFIN»
0.5
cdc42se2 CDC42 small effector protein 2 Danio rerio
TI:7955 None
 
C42S1_DANRE
ZFIN»
0.8
cdc42se1 CDC42 small effector protein 1 Danio rerio
TI:7955 None
 
A0A8V0Z1B4_CHICK
Ensembl»
0.0
LOC100859848 CRIB domain-containing protein Gallus gallus
TI:9031 None
   
A0A8V1AL84_CHICK
Ensembl»
0.0
CDC42SE1 CDC42 small effector 1 Gallus gallus
TI:9031 None
   
C42S1_CHICK
CTD»
0.0
CDC42SE1 CDC42 small effector protein 1 Gallus gallus
TI:9031 None
 
A0A8V0Y2B6_CHICK
Ensembl»
0.0
CDC42SE2 CDC42 small effector 2 Gallus gallus
TI:9031 None
   
Q19275_CAEEL
WormBase»
0.0
CELE_F09F7.5 F09F7.5 CRIB domain-containing protein Caenorhabditis elegans
TI:6239 None