Collated Gene Ontology terms

Biological process: small GTPase binding(2011, 2022, 2024) signaling adaptor activity(2019, 2024) actin binding(2024) protein kinase binding(2024) phospholipase binding(2024) identical protein binding(2024) actin monomer binding(2024) SH3 domain binding(2024) GTPase inhibitor activity(2003) Arp2/3 complex binding(2024)

Molecular function: regulation of Rho protein signal transduction2011, 2024 regulation of cell shape2006, 2024 phagocytosis2024 regulation of signal transduction2008, 2024 actin filament organization2024 small GTPase mediated signal transduction2006 signal transduction2003 regulation of stress fiber assembly2024 regulation of lamellipodium assembly2024 regulation of actin polymerization or depolymerization2024
regulation of actin filament polymerization2022 regulation of T cell antigen processing and presentation2024 positive regulation of transcription by RNA polymerase II2024 positive regulation of double-strand break repair via homologous recombination2024 negative regulation of stress fiber assembly2024 negative regulation of cell motility2024 negative regulation of JNK cascade2006 mitotic cytokinesis2024 mitotic actomyosin contractile ring assembly2024 midbrain-hindbrain boundary morphogenesis2013 immune response2024 establishment or maintenance of cell polarity2024 endocytosis2024 actin filament polymerization2024 actin filament branching2024 actin cortical patch assembly2024 Cdc42 protein signal transduction2024 Arp2/3 complex-mediated actin nucleation2024

Cellular component: plasma membrane2003, 2008, 2017, 2024 cytoskeleton2024 cytoplasm2022, 2024 cell junction2023, 2024 nucleus2024 phagocytic cup2024 cell projection2024 cell cortex2006, 2011 site of double-strand break2024 medial cortex2024
mating projection tip2024 cytosol2024 actin filament2024 actin cortical patch2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
C42S1_HUMAN
Ensembl»
1.8
CDC42SE1 CDC42 small effector protein 1 (CDC42-binding protein
SCIP1) (Small effector of CDC42 protein 1)		 Homo sapiens
TI:9606 None
 
C42S2_HUMAN
Ensembl»
1.6
CDC42SE2 CDC42 small effector protein 2
(Small effector of CDC42 protein 2)		 Homo sapiens
TI:9606 None
 
C42ES_DROME
FlyBase»
1.5
Spec2 CDC42 small effector protein homolog (Dspec) Drosophila melanogaster
TI:7227 None
 
C42S1_MOUSE
Ensembl»
1.5
Cdc42se1 CDC42 small effector protein 1 Mus musculus
TI:10090 None
 
C42S2_RAT
RGD»
1.5
Cdc42se2 CDC42 small effector protein 2 Rattus norvegicus
TI:10116 None
 
C42S1_DANRE
ZFIN»
0.8
cdc42se1 CDC42 small effector protein 1 Danio rerio
TI:7955 None
 
C42S2_DANRE
ZFIN»
0.5
cdc42se2 CDC42 small effector protein 2 Danio rerio
TI:7955 None
 
C42S2_MOUSE
Ensembl»
0.5
Cdc42se2 CDC42 small effector protein 2 Mus musculus
TI:10090 None
 
A0A1L8HPI8_XENLA
Xenbase»
0.0
cdc42se2l.S CDC42 small effector protein 2-A isoform X1 Xenopus laevis
TI:8355 None
   
A0A1L8HYP9_XENLA
Xenbase»
0.0
cdc42se2l.L CDC42 small effector protein 2 Xenopus laevis
TI:8355 None
   
A0A287AEN9_PIG
Ensembl»
0.0
CDC42SE2 CDC42 small effector 2 Sus scrofa
TI:9823 None
   
A0A2I2UVE0_FELCA
Ensembl»
0.0
CDC42SE2 CDC42 small effector 2 Felis catus
TI:9685 None
 
A0A3B3HU11_ORYLA
Ensembl»
0.0
cdc42se1 CDC42 small effector 1 Oryzias latipes
TI:8090 None
   
A0A3Q1NEY5_BOVIN
Ensembl»
0.0
CRIB domain-containing protein Bos taurus
TI:9913 None
   
A0A3Q1NGJ3_BOVIN
Ensembl»
0.0
CRIB domain-containing protein Bos taurus
TI:9913 None
   
A0A4X1W2X3_PIG
Ensembl»
0.0
CDC42SE1 CDC42 small effector 1 Sus scrofa
TI:9823 None
   
A0A5F5Y7U2_FELCA
Ensembl»
0.0
CDC42SE1 CDC42 small effector 1 Felis catus
TI:9685 None
 
A0A6I8P8D6_ORNAN
Ensembl»
0.0
CDC42SE1 CRIB domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7HIF4_STRPU
EnsemblMetazoa»
0.0
Wiskott-Aldrich syndrome protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7MZS2_STRPU
EnsemblMetazoa»
0.0
CRIB domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3N9L7_CANLF
Ensembl»
0.0
CDC42SE2 Uncharacterized protein Canis lupus
TI:9612 None
   
A0A8V0Y6B0_CHICK
Ensembl»
0.0
CDC42SE2 CDC42 small effector 2 Gallus gallus
TI:9031 None
   
A0A8V0Z1B4_CHICK
Ensembl»
0.0
LOC100859848 CRIB domain-containing protein Gallus gallus
TI:9031 None
   
A0A8V1AL84_CHICK
Ensembl»
0.0
CDC42SE1 CDC42 small effector protein 1 Gallus gallus
TI:9031 None
   
A0A9J7MJS5_BRAFL
CTD»
0.0
LOC118411509 CDC42 small effector protein 2-like Branchiostoma floridae
TI:7739 None
   
A7REW2_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g176973 CRIB domain-containing protein Nematostella vectensis
TI:45351 None
 
A8WJV2_CAEBR
WormBase»
0.0
CBG24041 CBG_24041 Protein CBG24041 Caenorhabditis briggsae
TI:6238 None
 
A9V3F9_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_33166 CRIB domain-containing protein Monosiga brevicollis
TI:81824 None
 
A9V6R1_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_38251 Non-specific serine/threonine protein kinase Monosiga brevicollis
TI:81824 None
 
B0BMN8_XENTR
Xenbase»
0.0
was WASP actin nucleation
promoting factor (Was protein)		 Xenopus tropicalis
TI:8364 None
 
B3RU45_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_55151 CRIB domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B7PT90_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW008485 Wiskott-aldrich syndrome protein, putative
(Wiskott-aldrich syndrome protein, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
B7PV65_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW007778 CRIB domain-containing protein Ixodes scapularis
TI:6945 None
 
C42S1_BOVIN
CTD»
0.0
CDC42SE1 CDC42 small effector protein 1 Bos taurus
TI:9913 None
 
C42S1_CHICK
CTD»
0.0
CDC42SE1 CDC42 small effector protein 1 Gallus gallus
TI:9031 None
 
C42S1_RAT
RGD»
0.0
Cdc42se1 CDC42 small effector protein 1 Rattus norvegicus
TI:10116 None
 
C42S1_XENTR
Xenbase»
0.0
cdc42se1 CDC42 small effector protein 1 Xenopus tropicalis
TI:8364 None
 
C42S2_BOVIN
Ensembl»
0.0
CDC42SE2 CDC42 small effector protein 2 Bos taurus
TI:9913 None
 
C4S1A_XENLA
Xenbase»
0.0
cdc42se1-a CDC42 small effector protein 1-A Xenopus laevis
TI:8355 None
 
C4S1B_XENLA
Xenbase»
0.0
cdc42se1-b CDC42 small effector protein 1-B Xenopus laevis
TI:8355 None
 
C4S2A_XENLA
Xenbase»
0.0
cdc42se2-a CDC42 small effector protein 2-A Xenopus laevis
TI:8355 None
 
C4S2A_XENTR
Xenbase»
0.0
cdc42se2-A CDC42 small effector protein 2-A Xenopus tropicalis
TI:8364 None
 
C4S2B_XENLA
Xenbase»
0.0
cdc42se2-b CDC42 small effector protein 2-B Xenopus laevis
TI:8355 None
 
C4S2B_XENTR
Xenbase»
0.0
cdc42se2-B CDC42 small effector protein 2-B Xenopus tropicalis
TI:8364 None
 
C4S2C_XENLA
Xenbase»
0.0
cdc42se2-c CDC42 small effector protein 2-C Xenopus laevis
TI:8355 None
 
D6WRY1_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_09513 CDC42 small effector
protein homolog-like Protein		 Tribolium castaneum
TI:7070 None
 
E9GG67_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_50104 Wiskott-Aldrich syndrome protein Daphnia pulex
TI:6669 None
 
E9H8T3_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_326794 CRIB domain-containing protein Daphnia pulex
TI:6669 None
 
F6SA08_MONDO
Ensembl»
0.0
WAS WASP actin nucleation promoting factor Monodelphis domestica
TI:13616 None
   
F6T0R1_MACMU
Ensembl»
0.0
CDC42SE1 CDC42 small effector 1
(CDC42 small effector protein 1)		 Macaca mulatta
TI:9544 None
 
F6TCM7_HORSE
Ensembl»
0.0
CDC42SE2 CDC42 small effector 2 Equus caballus
TI:9796 None
   
F6ZHW3_MONDO
Ensembl»
0.0
CDC42SE2 CDC42 small effector 2 Monodelphis domestica
TI:13616 None
   
F7GKB5_MONDO
Ensembl»
0.0
CDC42SE1 CDC42 small effector 1 Monodelphis domestica
TI:13616 None
   
G1K9D9_ANOCA
Ensembl»
0.0
CDC42SE2 CDC42 small effector 2 Anolis carolinensis
TI:28377 None
   
G3QYT6_GORGO
Ensembl»
0.0
CDC42SE1 CDC42 small effector 1 Gorilla gorilla
TI:9593 None
 
G3R8P0_GORGO
Ensembl»
0.0
CDC42SE2 CDC42 small effector 2 Gorilla gorilla
TI:9593 None
 
G7MTX9_MACMU
Ensembl»
0.0
CDC42SE2 CDC42 small effector protein 2 Macaca mulatta
TI:9544 None
 
H2M876_ORYLA
Ensembl»
0.0
cdc42se2 CDC42 small effector 2 Oryzias latipes
TI:8090 None
   
H2QZW3_PANTR
Ensembl»
0.0
CDC42SE1 CDC42 small effector 1 Pan troglodytes
TI:9598 None
 
H2R2H3_PANTR
Ensembl»
0.0
CDC42SE2 CDC42 small effector 2 Pan troglodytes
TI:9598 None
 
H2XYC4_CIOIN
Ensembl»
0.0
CRIB domain-containing protein Ciona intestinalis
TI:7719 None
 
H9GUV0_ANOCA
Ensembl»
0.0
CRIB domain-containing protein Anolis carolinensis
TI:28377 None
   
Q19275_CAEEL
WormBase»
0.0
CELE_F09F7.5 F09F7.5 CRIB domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q5KG31_CRYNJ
EnsemblFungi»
0.0
CNE05050 Wiskott-Aldrich syndrome protein Cryptococcus neoformans
TI:5207 None
 
Q7PTP8_ANOGA
EnsemblMetazoa»
0.0
1269168 AGAP003263-PA Anopheles gambiae
TI:7165 None
 
Q7Q2V6_ANOGA
EnsemblMetazoa»
0.0
1278391 AGAP001081-PA Anopheles gambiae
TI:7165 None
 
W5MNR8_LEPOC
Ensembl»
0.0
CDC42 small effector 2 Lepisosteus oculatus
TI:7918 None
 
W5N657_LEPOC
Ensembl»
0.0
CDC42 small effector protein 2-like Lepisosteus oculatus
TI:7918 None