Cluster UKP06384
- METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE
Standard knownness: 7.1; Custom knownness: None; Num. species: 64; Orthology database: Panther19.0; Protein members: 80
Collated Gene Ontology terms
Biological process:
methylthioribulose 1-phosphate dehydratase activity(2010, 2013, 2016, 2017, 2024)
zinc ion binding(2016, 2022, 2024)
metal ion binding(2024)
lyase activity(2024)
identical protein binding(2024)
catalytic activity(2024)
magnesium ion binding(2024)
hydrolase activity(2024)
acireductone synthase activity(2024)
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity(2024)
2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity2024
2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity2024
Molecular function: L-methionine salvage from methylthioadenosine2013, 2017, 2024 methionine biosynthetic process2024 L-methionine salvage from S-adenosylmethionine2024 apoptotic process2005, 2024 negative regulation of apoptotic process2013, 2016, 2024 regulation of ERK1 and ERK2 cascade2013, 2024 pyroptosis2016, 2024 protein homotetramerization2016, 2024 monosaccharide metabolic process2024 translation2021
Cellular component: cytoplasm2016, 2018, 2020, 2024 cytosol2009, 2010, 2011, 2013 membrane2024 nucleus2009, 2024 cytoskeleton2024
Phylogenetic distribution
| Chordates: | 22/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 4/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 14/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 1/4 | |
| Harosa: | 1/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 8/39 | |
| Archea: | 0/8 | |
| Bacteria: | 5/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
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B6K229_SCHJY EnsemblFungi» |
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SJAG_02293 | 5'-methylthioribulose-1-phosphate dehydratase |
Schizosaccharomyces japonicus TI:4897 None |
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A0A2A6CUL3_PRIPA EnsemblMetazoa» |
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WBGene00092541 | Aldolase_II domain-containing protein |
Pristionchus pacificus TI:54126 None |
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A0A3N7H8Z5_POPTR EnsemblPlants» |
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POPTR_011G118066 | Class II aldolase/adducin N-terminal domain-containing protein |
Populus trichocarpa TI:3694 None |
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A0A8I3PE93_CANLF Ensembl» |
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APIP | Class II aldolase/adducin N-terminal domain-containing protein |
Canis lupus TI:9612 None |
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B8C6J0_THAPS EnsemblProtists» |
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THAPSDRAFT_270286 | Class II aldolase/adducin N-terminal domain-containing protein |
Thalassiosira pseudonana TI:35128 None |
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D8QZV1_SELML EnsemblPlants» |
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SELMODRAFT_405839 | Class II aldolase/adducin N-terminal domain-containing protein |
Selaginella moellendorffii TI:88036 None |
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D8QZV9_SELML EnsemblPlants» |
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SELMODRAFT_405846 | Class II aldolase/adducin N-terminal domain-containing protein |
Selaginella moellendorffii TI:88036 None |
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D8TC30_SELML EnsemblPlants» |
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SELMODRAFT_431271 | Class II aldolase/adducin N-terminal domain-containing protein |
Selaginella moellendorffii TI:88036 None |
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D8TC38_SELML EnsemblPlants» |
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SELMODRAFT_431278 | Class II aldolase/adducin N-terminal domain-containing protein |
Selaginella moellendorffii TI:88036 None |
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K7LV33_SOYBN EnsemblPlants» |
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GLYMA_12G153200 | Class II aldolase/adducin N-terminal domain-containing protein |
Glycine max TI:3847 None |
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YFY6_SCHPO PomBase» |
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SPAC9.06c | Methylthioribulose-1-phosphate dehydratase-like protein |
Schizosaccharomyces pombe TI:4896 None |
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E3KUM5_PUCGT EnsemblFungi» |
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MDE1 | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Puccinia graminis TI:5297 None |
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F4NZV9_BATDJ EnsemblBacteria» |
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MDE1 | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Batrachochytrium dendrobatidis TI:109871 None |
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MTNB_ASHGO EnsemblFungi» |
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MDE1 | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Ashbya gossypii TI:33169 None |
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MTNB_ASPFU EnsemblFungi» |
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mde1 | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Aspergillus fumigatus TI:746128 None |
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MTNB_BACCR EnsemblBacteria» |
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mtnB | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Bacillus cereus TI:1396 None |
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MTNB_BACSU EnsemblBacteria» |
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mtnB | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Bacillus subtilis TI:1423 None |
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MTNB_CANAL EnsemblFungi» |
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MDE1 | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Candida albicans TI:5476 None |
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MTNB_CRYNJ EnsemblFungi» |
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MDE1 | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Cryptococcus neoformans TI:5207 None |
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MTNB_EMENI EnsemblFungi» |
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mde1 | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Emericella nidulans TI:162425 None |
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MTNB_LEPIN EnsemblBacteria» |
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mtnB | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Leptospira interrogans TI:173 None |
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MTNB_NEUCR EnsemblFungi» |
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mde-1 | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Neurospora crassa TI:5141 None |
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MTNB_PSEAE EnsemblBacteria» |
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mtnB | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Pseudomonas aeruginosa TI:287 None |
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MTNB_SCHJY EnsemblFungi» |
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mde1 | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Schizosaccharomyces japonicus TI:4897 None |
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MTNB_SCHPO PomBase» |
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mde1 | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Schizosaccharomyces pombe TI:4896 None |
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MTNB_SCLS1 EnsemblFungi» |
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mde1 | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Sclerotinia sclerotiorum TI:5180 None |
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MTNB_XANCP EnsemblBacteria» |
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mtnB | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Xanthomonas campestris TI:339 None |
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MTNB_YARLI EnsemblFungi» |
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MDE1 | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Yarrowia lipolytica TI:4952 None |
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MTNB_YEAST SGD» |
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MDE1 | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Saccharomyces cerevisiae TI:4932 None |
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A0A1L8GIP2_XENLA Xenbase» |
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apip.L | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog) |
Xenopus laevis TI:8355 None |
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A0A3Q2LAZ8_HORSE Ensembl» |
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APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) |
Equus caballus TI:9796 None |
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A0A5F8GU04_MONDO Ensembl» |
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APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) |
Monodelphis domestica TI:13616 None |
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A0A5G2R267_PIG Ensembl» |
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APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) |
Sus scrofa TI:9823 None |
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A0A803SYB5_ANOCA Ensembl» |
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APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog) |
Anolis carolinensis TI:28377 None |
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A0A8J0V8V4_XENLA Xenbase» |
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apip.S | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog) |
Xenopus laevis TI:8355 None |
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D3ZUI1_RAT RGD» |
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Apip | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) |
Rattus norvegicus TI:10116 None |
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F6PQB9_ORNAN Ensembl» |
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APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) |
Ornithorhynchus anatinus TI:9258 None |
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F7HS49_MACMU Ensembl» |
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APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) |
Macaca mulatta TI:9544 None |
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G3RWT9_GORGO Ensembl» |
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APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) |
Gorilla gorilla TI:9593 None |
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H2L5W1_ORYLA Ensembl» |
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apip | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog) |
Oryzias latipes TI:8090 None |
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H2Q3E7_PANTR Ensembl» |
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APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) |
Pan troglodytes TI:9598 None |
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M3VYQ9_FELCA Ensembl» |
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APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) |
Felis catus TI:9685 None |
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MTNB_BOVIN Ensembl» |
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APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) |
Bos taurus TI:9913 None |
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MTNB_CHICK Ensembl» |
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APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog) |
Gallus gallus TI:9031 None |
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MTNB_DANRE ZFIN» |
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apip | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog) |
Danio rerio TI:7955 None |
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MTNB_HUMAN Ensembl» |
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APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) (hAPIP) |
Homo sapiens TI:9606 None |
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MTNB_XENLA Xenbase» |
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apip | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog) |
Xenopus laevis TI:8355 None |
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MTNB_XENTR Xenbase» |
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apip | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog) |
Xenopus tropicalis TI:8364 None |
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W5LZG7_LEPOC Ensembl» |
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APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein homolog) |
Lepisosteus oculatus TI:7918 None |
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MTNB_MOUSE Ensembl» |
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Apip | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) (Monocyte/macrophage protein 19) |
Mus musculus TI:10090 None |
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A0A9K3E535_HELAN EnsemblPlants» |
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HanXRQr2_Chr14g0620661 | Methylthioribulose-1-phosphate dehydratase, class II aldolase/adducin domain superfamily |
Helianthus annuus TI:4232 None |
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A0A9K3EB18_HELAN EnsemblPlants» |
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HanXRQr2_Chr14g0653291 | Methylthioribulose-1-phosphate dehydratase, class II aldolase/adducin domain superfamily |
Helianthus annuus TI:4232 None |
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A0A9K3J2Q4_HELAN EnsemblPlants» |
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HanXRQr2_Chr05g0224231 | Methylthioribulose-1-phosphate dehydratase, class II aldolase/adducin domain superfamily |
Helianthus annuus TI:4232 None |
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A0A251VNF7_HELAN EnsemblPlants» |
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HannXRQ_Chr01g0015321 HanXRQr2_Chr01g0023261 | Methylthioribulose-1-phosphate dehydratase, class II aldolase/adducin domain superfamily (Putative class II aldolase/adducin, Methylthioribulose-1-phosphate dehydratase) |
Helianthus annuus TI:4232 None |
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A0A1U8KTC0_GOSHI Ensembl» |
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LOC107919256 | Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 |
Gossypium hirsutum TI:3635 None |
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A0A1U8NRV0_GOSHI Ensembl» |
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LOC107951147 | Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 |
Gossypium hirsutum TI:3635 None |
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A0A1U8IIY4_GOSHI Ensembl» |
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LOC107897216 | Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 isoform X1 |
Gossypium hirsutum TI:3635 None |
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A0A061E327_THECC EnsemblPlants» |
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TCM_046722 | Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [Includes: Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109); Enolase-phosphatase E1 (EC 3.1.3.77) (2,3-diketo-5-methylthio-1-phosphopentane phosphatase)] |
Theobroma cacao TI:3641 None |
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A0A2K3E5R9_CHLRE EnsemblPlants» |
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CHLRE_01g016528v5 | Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [Includes: Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109); Enolase-phosphatase E1 (EC 3.1.3.77) (2,3-diketo-5-methylthio-1-phosphopentane phosphatase)] |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2R6XT43_MARPO EnsemblPlants» |
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MARPO_0003s0138 | Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [Includes: Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109); Enolase-phosphatase E1 (EC 3.1.3.77) (2,3-diketo-5-methylthio-1-phosphopentane phosphatase)] |
Marchantia polymorpha TI:3197 None |
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D8QZT1_SELML EnsemblPlants» |
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SELMODRAFT_266773 | Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [Includes: Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109); Enolase-phosphatase E1 (EC 3.1.3.77) (2,3-diketo-5-methylthio-1-phosphopentane phosphatase)] |
Selaginella moellendorffii TI:88036 None |
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D8TC57_SELML EnsemblPlants» |
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SELMODRAFT_187281 | Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [Includes: Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109); Enolase-phosphatase E1 (EC 3.1.3.77) (2,3-diketo-5-methylthio-1-phosphopentane phosphatase)] |
Selaginella moellendorffii TI:88036 None |
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A0A7M7TH15_STRPU EnsemblMetazoa» |
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Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Strongylocentrotus purpuratus TI:7668 None |
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A0A9J7KXV3_BRAFL CTD» |
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LOC118413307 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Branchiostoma floridae TI:7739 None |
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A0A9J7KZM7_BRAFL CTD» |
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LOC118413308 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Branchiostoma floridae TI:7739 None |
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B7PIM8_IXOSC EnsemblMetazoa» |
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8029502 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Ixodes scapularis TI:6945 None |
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D6WY90_TRICA EnsemblMetazoa» |
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AUGUSTUS-3.0.2_02174 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Tribolium castaneum TI:7070 None |
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F0ZL55_DICPU EnsemblProtists» |
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DICPUDRAFT_33571 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Dictyostelium purpureum TI:5786 None |
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F6UIW1_CIOIN Ensembl» |
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Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Ciona intestinalis TI:7719 None |
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MTNB_ANOGA EnsemblMetazoa» |
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AGAP000470 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Anopheles gambiae TI:7165 None |
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MTNB_CAEEL WormBase» |
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ZC373.5 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Caenorhabditis elegans TI:6239 None |
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MTNB_DICDI dictyBase» |
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DDB_G0284915 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Dictyostelium discoideum TI:44689 None |
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MTNB_DROME FlyBase» |
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CG11134 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Drosophila melanogaster TI:7227 None |
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MTNB_LEIMA EnsemblProtists» |
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LmjF28.1840 LmjF_28_1840 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Leishmania major TI:5664 None |
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MTNB_MONBE EnsemblProtists» |
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29994 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Monosiga brevicollis TI:81824 None |
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MTNB_NEMVE EnsemblMetazoa» |
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v1g197093 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Nematostella vectensis TI:45351 None |
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MTNB_TRIAD EnsemblMetazoa» |
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TRIADDRAFT_64275 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Trichoplax adhaerens TI:10228 None |
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T1FYI7_HELRO EnsemblMetazoa» |
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20213885 | Probable methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) |
Helobdella robusta TI:6412 None |
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A8WRQ1_CAEBR WormBase» |
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CBG01970 CBG_01970 | Protein CBG01970 |
Caenorhabditis briggsae TI:6238 None |
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A0A251URB8_HELAN EnsemblPlants» |
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HannXRQ_Chr05g0153011 | Putative class II aldolase/adducin N-terminal, Methylthioribulose-1-phosphate dehydratase |
Helianthus annuus TI:4232 None |
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