Collated Gene Ontology terms

Biological process: methylthioribulose 1-phosphate dehydratase activity(2010, 2013, 2016, 2017, 2024) zinc ion binding(2016, 2022, 2024) metal ion binding(2024) lyase activity(2024) identical protein binding(2024) catalytic activity(2024) magnesium ion binding(2024) hydrolase activity(2024) acireductone synthase activity(2024) 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity(2024)
2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity2024

Molecular function: L-methionine salvage from methylthioadenosine2013, 2017, 2024 methionine biosynthetic process2024 L-methionine salvage from S-adenosylmethionine2024 apoptotic process2005, 2024 negative regulation of apoptotic process2013, 2016, 2024 regulation of ERK1 and ERK2 cascade2013, 2024 pyroptosis2016, 2024 protein homotetramerization2016, 2024 monosaccharide metabolic process2024 translation2021

Cellular component: cytoplasm2016, 2018, 2020, 2024 cytosol2009, 2010, 2011, 2013 membrane2024 nucleus2009, 2024 cytoskeleton2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 8/39 
Archea: 0/8 
Bacteria: 5/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
MTNB_HUMAN
Ensembl»
7.1
APIP Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase)
(EC 4.2.1.109) (APAF1-interacting protein) (hAPIP)		 Homo sapiens
TI:9606 None
 
D3ZUI1_RAT
RGD»
5.5
Apip Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase)
(EC 4.2.1.109) (APAF1-interacting protein)		 Rattus norvegicus
TI:10116 None
   
MTNB_MOUSE
Ensembl»
5.4
Apip Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC
4.2.1.109) (APAF1-interacting protein) (Monocyte/macrophage protein 19)		 Mus musculus
TI:10090 None
 
MTNB_YEAST
SGD»
3.2
MDE1 Methylthioribulose-1-phosphate dehydratase (MTRu-1-P
dehydratase) (EC 4.2.1.109)		 Saccharomyces cerevisiae
TI:4932 None
 
MTNB_CHICK
Ensembl»
2.5
APIP Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase)
(EC 4.2.1.109) (APAF1-interacting protein homolog)		 Gallus gallus
TI:9031 None
 
MTNB_DANRE
ZFIN»
2.5
apip Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase)
(EC 4.2.1.109) (APAF1-interacting protein homolog)		 Danio rerio
TI:7955 None
 
MTNB_CAEEL
WormBase»
2.0
ZC373.5 Probable methylthioribulose-1-phosphate dehydratase
(MTRu-1-P dehydratase) (EC 4.2.1.109)		 Caenorhabditis elegans
TI:6239 None
 
MTNB_DICDI
dictyBase»
2.0
DDB_G0284915 Probable methylthioribulose-1-phosphate dehydratase
(MTRu-1-P dehydratase) (EC 4.2.1.109)		 Dictyostelium discoideum
TI:44689 None
 
MTNB_DROME
FlyBase»
2.0
CG11134 Probable methylthioribulose-1-phosphate dehydratase
(MTRu-1-P dehydratase) (EC 4.2.1.109)		 Drosophila melanogaster
TI:7227 None
 
MTNB_SCHPO
PomBase»
1.0
mde1 Methylthioribulose-1-phosphate dehydratase (MTRu-1-P
dehydratase) (EC 4.2.1.109)		 Schizosaccharomyces pombe
TI:4896 None
 
YFY6_SCHPO
PomBase»
1.0
SPAC9.06c Methylthioribulose-1-phosphate
dehydratase-like protein		 Schizosaccharomyces pombe
TI:4896 None