Collated Gene Ontology terms

Biological process: zinc ion binding(2006, 2014, 2022, 2025) metal ion binding(2025) ubiquitin-protein transferase activity(2014, 2025) DNA binding(2025) ubiquitin protein ligase activity(2005, 2020, 2025) transferase activity(2025) acyltransferase activity, transferring groups other than amino-acyl groups(2025) N-acetyltransferase activity(2005)

Molecular function: mRNA splicing, via spliceosome2013, 2015, 2019, 2025 protein ubiquitination2014, 2018, 2024, 2025 mRNA processing2025 RNA splicing2025 negative regulation of chemokine-mediated signaling pathway2018, 2025 snoRNA splicing2013, 2025 DNA repair2025 DNA damage response2025 generation of catalytic spliceosome for first transesterification step2013, 2025 regulation of RNA splicing2015
neuron differentiation2013

Cellular component: U2-type spliceosomal complex2013, 2015, 2017, 2025 nucleus2009, 2012, 2013, 2018, 2019, 2025 spliceosomal complex2013, 2020, 2025 nucleoplasm2022, 2025 U2-type precatalytic spliceosome2019, 2025 nuclear speck2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 1/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 40/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A3B6ISV0_WHEAT
EnsemblPlants»
0.0
Zinc finger CCCH domain-containing protein 1 Triticum aestivum
TI:4565 None
   
A0A3B6JMH3_WHEAT
EnsemblPlants»
0.0
Uncharacterized protein Triticum aestivum
TI:4565 None
   
A0A3Q7F805_SOLLC
EnsemblPlants»
0.0
C3H1-type domain-containing protein Solanum lycopersicum
TI:4081 None
   
A0A5F8GS30_MONDO
Ensembl»
0.0
Ring finger protein 113A Monodelphis domestica
TI:13616 None
   
A0A7M7NXP4_STRPU
EnsemblMetazoa»
0.0
RING finger protein 113A Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7RAQ4_STRPU
EnsemblMetazoa»
0.0
RING finger protein 113A Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3N1Q1_CANLF
Ensembl»
0.0
Uncharacterized protein Canis lupus
TI:9612 None
   
A0ABI7ZZ80_FELCA
Ensembl»
0.0
Ring finger protein 113A Felis catus
TI:9685 None
   
G3RML9_GORGO
Ensembl»
0.0
Ring finger protein 113B Gorilla gorilla
TI:9593 None
 
H3GHT1_PHYRM
EnsemblProtists»
0.0
RING-type E3 ubiquitin transferase Phytophthora ramorum
TI:164328 None
 
M4EWT3_BRACM
EnsemblPlants»
0.0
C3H1-type domain-containing protein Brassica campestris
TI:3711 None
   
M4F5T3_BRACM
EnsemblPlants»
0.0
RING-type domain-containing protein Brassica campestris
TI:3711 None
   
W5N1K5_LEPOC
Ensembl»
0.0
Ring finger protein 113A Lepisosteus oculatus
TI:7918 None
 
A0A072U502_MEDTR
EnsemblPlants»
0.0
11434789 Putative transcription factor C3H family
(RING zinc finger protein, putative)		 Medicago truncatula
TI:3880 None
 
Q7QIT7_ANOGA
EnsemblMetazoa»
0.0
1270036 AGAP007068-PA Anopheles gambiae
TI:7165 None
 
T1FN79_HELRO
EnsemblMetazoa»
0.0
20210277 RING finger protein 113A Helobdella robusta
TI:6412 None
 
W1P9C4_AMBTC
euHCVdb»
0.0
AMTR_s00077p00108560 C3H1-type domain-containing protein Amborella trichopoda
TI:13333 None
 
D6WQ47_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_09871 RING finger protein 113A-like Protein Tribolium castaneum
TI:7070 None
 
C3H1_ARATH
TAIR»
1.0
At1g01350 Zinc finger CCCH
domain-containing protein 1 (AtC3H1)		 Arabidopsis thaliana
TI:3702 None
 
A0A178UZR1_ARATH
TAIR»
1.0
At4g01023 RING/U-box superfamily protein Arabidopsis thaliana
TI:3702 None
 
C3H51_ARATH
TAIR»
1.0
At5g06420 Zinc finger CCCH
domain-containing protein 51 (AtC3H51)		 Arabidopsis thaliana
TI:3702 None
 
F4NU83_BATDJ
euHCVdb»
0.0
BATDEDRAFT_4427 Pre-mRNA-splicing factor CWC24 Batrachochytrium dendrobatidis
TI:109871 None
 
A0A3P6A7H4_BRACM
EnsemblPlants»
0.0
BRAA02T07420Z BRAPAZ1V2_A02P30040.2 RING-type domain-containing protein Brassica campestris
TI:3711 None
 
A0A078G815_BRANA
euHCVdb»
0.0
BnaA01g33980D (rape) hypothetical
protein (BnaA01g33980D protein)		 Brassica napus
TI:3708 None
 
A0A078FQN8_BRANA
euHCVdb»
0.0
BnaC05g00630D (rape) hypothetical
protein (BnaC05g00630D protein)		 Brassica napus
TI:3708 None
 
A0A2K3DMB1_CHLRE
euHCVdb»
0.0
CHLRE_06g254650v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A067G2P3_CITSI
euHCVdb»
0.0
CISIN_1g020671mg C3H1-type domain-containing protein Citrus sinensis
TI:2711 None
 
CWC24_CANAL
EnsemblFungi»
0.0
CWC24 Pre-mRNA-splicing factor CWC24 Candida albicans
TI:5476 None
 
CWC24_CRYD1
EnsemblFungi»
0.0
CWC24 Pre-mRNA-splicing factor CWC24 Cryptococcus deneoformans
TI:40410 None
 
CWC24_EREGS
EnsemblFungi»
0.0
CWC24 Pre-mRNA-splicing factor CWC24 Eremothecium gossypii
TI:33169 None
 
CWC24_YARLI
EnsemblFungi»
0.0
CWC24 Pre-mRNA-splicing factor CWC24 Yarrowia lipolytica
TI:4952 None
 
CWC24_YEAST
SGD»
4.6
CWC24 Pre-mRNA-splicing factor CWC24 (Complexed
with CEF1 protein 24)		 Saccharomyces cerevisiae
TI:4932 None
 
A0A0A0KFS0_CUCSA
neXtProt»
0.0
Csa_6G382870 Zinc finger CCCH domain-containing protein 1 Cucumis sativus
TI:3659 None
 
E9HDM0_DAPPU
neXtProt»
0.0
DAPPUDRAFT_112971 Uncharacterized protein Daphnia pulex
TI:6669 None
 
F0ZPN7_DICPU
TubercuList»
0.0
DICPUDRAFT_80146 Zinc finger protein Dictyostelium purpureum
TI:5786 None
 
C4M749_ENTH1
TubercuList»
0.0
EHI_192080 Zinc finger protein, putative Entamoeba histolytica
TI:5759 None
 
E9HPZ0_DAPPU
euHCVdb»
0.0
EOG090X09Q6 EOG090X09Q6 Daphnia pulex
TI:6669 None
 
A0AAD9WJI5_EUCGR
neXtProt»
0.0
EUGRSUZ_L01590 Uncharacterized protein Eucalyptus grandis
TI:71139 None 		 
 
I1KXE8_SOYBN
EnsemblPlants»
0.0
GLYMA_08G286000 C3H1-type domain-containing protein Glycine max
TI:3847 None
 
A0A804K802_MUSAM
EnsemblPlants»
0.0
GSMUA_100250.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0C208_PARTE
neXtProt»
0.0
GSPATT00034302001 RING-type E3 ubiquitin transferase Paramecium tetraurelia
TI:5888 None
 
A0A251V0X4_HELAN
neXtProt»
0.0
HannXRQ_Chr04g0120251 HanXRQr2_Chr04g0182251 Putative zinc finger (CCCH-type/C3HC4-type RING finger)
family protein (Transcription factor C3H family)		 Helianthus annuus
TI:4232 None
 
B7QM34_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW023200 RING finger motif containing protein Ixodes scapularis
TI:6945 None
 
A0A7U2FES2_PHANO
TubercuList»
0.0
JI435_163970 Pre-mRNA-splicing factor CWC24 Phaeosphaeria nodorum
TI:13684 None
 
A0A1Y1HVP4_KLENI
euHCVdb»
0.0
KFL_001200240 C3H1-type domain-containing protein Klebsormidium nitens
TI:105231 None
 
F6SAN1_HORSE
Ensembl»
0.0
LOC100055218 Ring finger protein 113A Equus caballus
TI:9796 None
   
B4FWN6_MAIZE
EnsemblPlants»
0.0
LOC100279943 Zinc finger CCCH domain-containing protein 1 Zea mays
TI:4577 None
 
G1KMH1_ANOCA
Ensembl»
0.0
LOC100563669 Ring finger protein 113A Anolis carolinensis
TI:28377 None
   
K7KS04_SOYBN
EnsemblPlants»
0.0
LOC100787434 C3H1-type domain-containing protein Glycine max
TI:3847 None
 
I1JKM9_SOYBN
EnsemblPlants»
0.0
LOC100817146 C3H zinc finger protein Glycine max
TI:3847 None
 
I1HZA5_BRADI
EnsemblPlants»
0.0
LOC100840636 C3H1-type domain-containing protein Brachypodium distachyon
TI:15368 None
 
K3YU04_SETIT
EnsemblPlants»
0.0
LOC101769097 RING-type E3 ubiquitin transferase Setaria italica
TI:4555 None
 
M1B2E5_SOLTU
EnsemblPlants»
0.0
LOC102594530 RING finger protein 113A Solanum tuberosum
TI:4113 None
   
A0A1U8Q8A7_NELNU
euHCVdb»
0.0
LOC104603278 Zinc finger CCCH domain-containing protein 1 Nelumbo nucifera
TI:4432 None
   
A0A1S4CMV0_TOBAC
euHCVdb»
0.0
LOC107820773 Zinc finger CCCH domain-containing protein 1 Nicotiana tabacum
TI:4097 None
   
A0A1S4DEQ9_TOBAC
euHCVdb»
0.0
LOC107829014 Zinc finger CCCH
domain-containing protein 1-like		 Nicotiana tabacum
TI:4097 None
   
A0A1U8IEL3_GOSHI
euHCVdb»
0.0
LOC107893706 Zinc finger CCCH domain-containing protein 1 Gossypium hirsutum
TI:3635 None
   
A0A1U8JUK9_GOSHI
euHCVdb»
0.0
LOC107910592 Zinc finger CCCH domain-containing
protein 1 isoform X1		 Gossypium hirsutum
TI:3635 None
   
A0A6P9EHM2_JUGRE
neXtProt»
0.0
LOC108983656 Zinc finger CCCH domain-containing
protein 1-like isoform X1		 Juglans regia
TI:51240 None
   
A0A2I4F8E7_JUGRE
euHCVdb»
0.0
LOC108996460 Zinc finger CCCH
domain-containing protein 1-like		 Juglans regia
TI:51240 None
   
A0A9R0K2J7_SPIOL
euHCVdb»
0.0
LOC110794777 Zinc finger CCCH domain-containing protein 1 Spinacia oleracea
TI:3562 None
   
A0ABI7YXT7_FELCA
Ensembl»
0.0
LOC111556217 Ring finger protein 113A Felis catus
TI:9685 None
   
A9SSR1_PHYPA
EnsemblPlants»
0.0
LOC112285777 Uncharacterized protein Physcomitrium patens
TI:3218 None
 
A0A2I4DUT4_JUGRE
euHCVdb»
0.0
LOC118344279 Zinc finger CCCH
domain-containing protein 1-like		 Juglans regia
TI:51240 None
   
A0A9J7HDV5_BRAFL
euHCVdb»
0.0
LOC118403281 E3 ubiquitin-protein ligase RNF113A-like Branchiostoma floridae
TI:7739 None
   
A0A3B6HSX0_WHEAT
EnsemblPlants»
0.0
LOC123085307 Zinc finger CCCH domain-containing protein 1 Triticum aestivum
TI:4565 None
   
A0A3B6PQJ0_WHEAT
EnsemblPlants»
0.0
LOC123137882 Uncharacterized protein Triticum aestivum
TI:4565 None
   
F2DBY5_HORVV
EnsemblPlants»
0.0
LOC123449135 Predicted protein Hordeum vulgare
TI:4513 None
 
Q67EQ6_CIOIN
Ensembl»
0.0
LOC494419 Zinc finger protein 183 Ciona intestinalis
TI:7719 None
 
A0A9R1V3B4_LACSA
neXtProt»
0.0
LSAT_V11C700343030 Zinc finger CCCH domain-containing protein 1 Lactuca sativa
TI:4236 None
 
A0A251LWF8_MANES
euHCVdb»
0.0
MANES_02G115900 C3H1-type domain-containing protein Manihot esculenta
TI:3983 None
 
A0A2R6WQP1_MARPO
neXtProt»
0.0
MARPO_0066s0113 RING-type E3 ubiquitin transferase Marchantia polymorpha
TI:3197 None
 
A0A022QWE9_ERYGU
neXtProt»
0.0
MIMGU_mgv1a009713mg RING-type E3 ubiquitin transferase Erythranthe guttata
TI:4155 None
 
A9UPI2_MONBE
neXtProt»
0.0
MONBRDRAFT_2116 RING-type E3 ubiquitin transferase Monosiga brevicollis
TI:81824 None
 
A0A072U5J1_MEDTR
EnsemblPlants»
0.0
MTR_7g108868 MTR_8g058593 Zinc finger C-x8-C-x5-C-x3-H type protein Medicago truncatula
TI:3880 None
 
A0A072TQE4_MEDTR
EnsemblPlants»
0.0
MTR_8g058607 Zinc finger C-x8-C-x5-C-x3-H type protein Medicago truncatula
TI:3880 None
 
A7SUV2_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g193827 RING finger protein 113A Nematostella vectensis
TI:45351 None
 
C3H15_ORYSJ
EnsemblPlants»
0.0
Os02g0301000 LOC_Os02g19804 Zinc finger CCCH
domain-containing protein 15 (OsC3H15)		 Oryza sativa
TI:4530 None
 
Q8IL33_PLAF7
TubercuList»
0.0
PF3D7_1443800 Pre-mRNA-splicing factor CWC24, putative Plasmodium falciparum
TI:5833 None
 
E3JVB9_PUCGT
TubercuList»
0.0
PGTG_01325 Pre-mRNA-splicing factor CWC24 Puccinia graminis
TI:5297 None
 
A0A2K1XT33_POPTR
neXtProt»
0.0
POPTR_014G097300 C3H family protein Populus trichocarpa
TI:3694 None
 
A0A251NX62_PRUPE
euHCVdb»
0.0
PRUPE_6G288300 Zinc finger CCCH domain-containing protein 1 Prunus persica
TI:3760 None
 
A0A251N9A3_PRUPE
euHCVdb»
0.0
PRUPE_7G095500 C3H1-type domain-containing protein Prunus persica
TI:3760 None
 
A0A251UG64_HELAN
euHCVdb»
0.0
R113B Putative RING finger protein
(Transcription factor C3H family)		 Helianthus annuus
TI:4232 None
 
B9S849_RICCO
euHCVdb»
0.0
RCOM_0693420 RING finger protein 113A, putative Ricinus communis
TI:3988 None
 
B9S864_RICCO
euHCVdb»
0.0
RCOM_0694470 RING finger protein 113A, putative Ricinus communis
TI:3988 None
 
A0A140T863_BOVIN
Ensembl»
0.0
RNF113A Ring finger protein 113A Bos taurus
TI:9913 None
   
A0A287BM93_PIG
Ensembl»
0.0
RNF113A Ring finger protein 113A Sus scrofa
TI:9823 None
   
A0A8I3PFD4_CANLF
Ensembl»
0.0
RNF113A Ring finger protein 113A Canis lupus
TI:9612 None
   
A0ABI7VYE7_FELCA
Ensembl»
0.0
RNF113A Ring finger protein 113A Felis catus
TI:9685 None
   
F6V216_MACMU
Ensembl»
0.0
RNF113A RING finger protein 113A Macaca mulatta
TI:9544 None
 
F6XY35_HORSE
Ensembl»
0.0
RNF113A Ring finger protein 113A Equus caballus
TI:9796 None
   
F7E8Y2_ORNAN
Ensembl»
0.0
RNF113A Ring finger protein 113A Ornithorhynchus anatinus
TI:9258 None
   
G3QIS1_GORGO
Ensembl»
0.0
RNF113A Ring finger protein 113A Gorilla gorilla
TI:9593 None
 
H2LAW6_ORYLA
Ensembl»
0.0
RNF113A Ring finger protein 113A Oryzias latipes
TI:8090 None
   
H2QZ23_PANTR
Ensembl»
0.0
RNF113A Ring finger protein 113A Pan troglodytes
TI:9598 None
 
R113A_BOVIN
CTD»
0.0
RNF113A E3 ubiquitin-protein ligase RNF113A (EC 2.3.2.27) (RING
finger protein 113A) (Zinc finger protein 183)		 Bos taurus
TI:9913 None
 
R113A_HUMAN
Ensembl»
4.8
RNF113A E3 ubiquitin-protein ligase RNF113A (EC 2.3.2.27) (Cwc24 homolog)
(RING finger protein 113A) (Zinc finger protein 183)		 Homo sapiens
TI:9606 None
 
A0A5F8AAN5_MACMU
Ensembl»
0.0
RNF113B Ring finger protein 113B Macaca mulatta
TI:9544 None
   
A0A8V0ZLA4_CHICK
Ensembl»
1.0
RNF113B Ring finger protein 113B Gallus gallus
TI:9031 None
   
H2Q7R0_PANTR
Ensembl»
0.0
RNF113B Ring finger protein 113B Pan troglodytes
TI:9598 None
 
R113B_HUMAN
Ensembl»
1.0
RNF113B RING finger protein 113B
(Zinc finger protein 183-like 1)		 Homo sapiens
TI:9606 None
 
Q8R3P8_MOUSE
Ensembl»
3.0
Rnf113a1 Ring finger protein 113A1 Mus musculus
TI:10090 None
 
Q14B01_MOUSE
Ensembl»
3.0
Rnf113a2 Ring finger protein 113A2 Mus musculus
TI:10090 None
 
Q67ER1_RAT
RGD»
1.0
Rnf113a2 Ring finger protein 113A2 Rattus norvegicus
TI:10116 None
 
D8R3K9_SELML
neXtProt»
0.0
SELMODRAFT_406998 Zinc finger CCCH domain-containing protein 1 Selaginella moellendorffii
TI:88036 None
 
D8SI98_SELML
neXtProt»
0.0
SELMODRAFT_422399 Zinc finger CCCH domain-containing protein 1 Selaginella moellendorffii
TI:88036 None
 
C5XZF5_SORBI
euHCVdb»
0.0
SORBI_3004G113700 C3H1-type domain-containing protein Sorghum bicolor
TI:4558 None
 
A7F1F7_SCLS1
euHCVdb»
0.0
SS1G_11427 Pre-mRNA-splicing factor CWC24 Sclerotinia sclerotiorum
TI:5180 None
 
A0A2G3A9I4_CAPAN
euHCVdb»
0.0
T459_05983 Zinc finger CCCH domain-containing protein 1 Capsicum annuum
TI:4072 None
 
A0A061EKN3_THECC
euHCVdb»
0.0
TCM_020255 Zinc finger family protein Theobroma cacao
TI:3641 None
 
A0A061F796_THECC
neXtProt»
0.0
TCM_031427 Zinc finger (CCCH-type/C3HC4-type RING
finger) family protein, putative		 Theobroma cacao
TI:3641 None
 
B8LCU0_THAPS
neXtProt»
0.0
THAPSDRAFT_25179 Uncharacterized protein Thalassiosira pseudonana
TI:35128 None
 
B3RMM5_TRIAD
CTD»
0.0
TRIADDRAFT_20796 RING finger protein 113A Trichoplax adhaerens
TI:10228 None
 
A2D8J3_TRIV3
TubercuList»
0.0
TVAG_185490 Pre-mRNA-splicing factor CWC24 Trichomonas vaginalis
TI:5722 None
 
A2FRZ9_TRIV3
TubercuList»
0.0
TVAG_200630 C3H1-type domain-containing protein Trichomonas vaginalis
TI:5722 None
 
D7UCN8_VITVI
euHCVdb»
0.0
VIT_15s0046g01030 Zinc finger CCCH domain-containing protein 1 Vitis vinifera
TI:29760 None
 
A0A8R1V2S3_PRIPA
EnsemblMetazoa»
0.0
WBGene00304693 Zinc finger protein Pristionchus pacificus
TI:54126 None
   
A0A0K9PWK0_ZOSMR
euHCVdb»
0.0
ZOSMA_14G00700 Zinc finger CCCH domain-containing protein 1 Zostera marina
TI:29655 None
 
CWC24_NEUCR
EnsemblFungi»
0.0
cwc-24 Pre-mRNA-splicing factor cwc-24 Neurospora crassa
TI:5141 None
 
CWC24_ASPFU
EnsemblFungi»
0.0
cwc24 Pre-mRNA-splicing factor cwc24 Aspergillus fumigatus
TI:746128 None
 
CWC24_EMENI
EnsemblFungi»
0.0
cwc24 Pre-mRNA-splicing factor cwc24 Emericella nidulans
TI:162425 None
 
B6K3C8_SCHJY
TubercuList»
0.0
cwf24 Zf-C3HC4 type /GCN5-like
N acetyltransferase fusion protein		 Schizosaccharomyces japonicus
TI:4897 None
 
CWC24_SCHPO
PomBase»
2.5
cwf24 Pre-mRNA-splicing factor cwf24 (Complexed
with cdc5 protein 24)		 Schizosaccharomyces pombe
TI:4896 None
 
Q9VDP8_DROME
FlyBase»
4.1
mdlc CG4973 protein (CG4973-PA)
(LD35003p) (Midlife crisis)		 Drosophila melanogaster
TI:7227 None
 
Q67EQ5_CAEBR
WormBase»
0.0
rnf-113 Protein CBR-TAG-331 (Zinc finger protein 183) Caenorhabditis briggsae
TI:6238 None
 
RN113_CAEEL
WormBase»
2.6
rnf-113 Probable E3 ubiquitin-protein ligase rnf113 (EC
2.3.2.27) (RING finger protein 113 homolog)		 Caenorhabditis elegans
TI:6239 None
 
RN113_DICDI
dictyBase»
1.0
rnf113 RING finger protein 113 homolog Dictyostelium discoideum
TI:44689 None
 
Q28EQ7_XENTR
Xenbase»
0.0
rnf113a RING finger protein 113A
(Zinc finger protein 183)		 Xenopus tropicalis
TI:8364 None
 
Q6DRF0_DANRE
ZFIN»
1.0
rnf113a E3 ubiquitin-protein ligase RNF113A (EC 2.3.2.27) (Ring
finger protein 113A) (Zinc finger protein 183-like 1)		 Danio rerio
TI:7955 None
 
A3KND7_XENLA
Xenbase»
0.0
rnf113a.S LOC446953 protein (Ring finger
protein 113A S homeolog)		 Xenopus laevis
TI:8355 None