Collated Gene Ontology terms

Biological process: zinc ion binding(2006, 2014, 2022, 2025) metal ion binding(2025) ubiquitin-protein transferase activity(2014, 2025) DNA binding(2025) ubiquitin protein ligase activity(2005, 2020, 2025) transferase activity(2025) acyltransferase activity, transferring groups other than amino-acyl groups(2025) N-acetyltransferase activity(2005)

Molecular function: mRNA splicing, via spliceosome2013, 2015, 2019, 2025 protein ubiquitination2014, 2018, 2024, 2025 mRNA processing2025 RNA splicing2025 negative regulation of chemokine-mediated signaling pathway2018, 2025 snoRNA splicing2013, 2025 DNA repair2025 DNA damage response2025 generation of catalytic spliceosome for first transesterification step2013, 2025 regulation of RNA splicing2015
neuron differentiation2013

Cellular component: U2-type spliceosomal complex2013, 2015, 2017, 2025 nucleus2009, 2012, 2013, 2018, 2019, 2025 spliceosomal complex2013, 2020, 2025 nucleoplasm2022, 2025 U2-type precatalytic spliceosome2019, 2025 nuclear speck2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 1/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 40/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
C3H1_ARATH
TAIR»
1.0
At1g01350 Zinc finger CCCH
domain-containing protein 1 (AtC3H1)		 Arabidopsis thaliana
TI:3702 None
 
A0A178UZR1_ARATH
TAIR»
1.0
At4g01023 RING/U-box superfamily protein Arabidopsis thaliana
TI:3702 None
 
C3H51_ARATH
TAIR»
1.0
At5g06420 Zinc finger CCCH
domain-containing protein 51 (AtC3H51)		 Arabidopsis thaliana
TI:3702 None
 
CWC24_YEAST
SGD»
4.6
CWC24 Pre-mRNA-splicing factor CWC24 (Complexed
with CEF1 protein 24)		 Saccharomyces cerevisiae
TI:4932 None
 
R113A_HUMAN
Ensembl»
4.8
RNF113A E3 ubiquitin-protein ligase RNF113A (EC 2.3.2.27) (Cwc24 homolog)
(RING finger protein 113A) (Zinc finger protein 183)		 Homo sapiens
TI:9606 None
 
A0A8V0ZLA4_CHICK
Ensembl»
1.0
RNF113B Ring finger protein 113B Gallus gallus
TI:9031 None
   
R113B_HUMAN
Ensembl»
1.0
RNF113B RING finger protein 113B
(Zinc finger protein 183-like 1)		 Homo sapiens
TI:9606 None
 
Q8R3P8_MOUSE
Ensembl»
3.0
Rnf113a1 Ring finger protein 113A1 Mus musculus
TI:10090 None
 
Q14B01_MOUSE
Ensembl»
3.0
Rnf113a2 Ring finger protein 113A2 Mus musculus
TI:10090 None
 
Q67ER1_RAT
RGD»
1.0
Rnf113a2 Ring finger protein 113A2 Rattus norvegicus
TI:10116 None
 
CWC24_SCHPO
PomBase»
2.5
cwf24 Pre-mRNA-splicing factor cwf24 (Complexed
with cdc5 protein 24)		 Schizosaccharomyces pombe
TI:4896 None
 
Q9VDP8_DROME
FlyBase»
4.1
mdlc CG4973 protein (CG4973-PA)
(LD35003p) (Midlife crisis)		 Drosophila melanogaster
TI:7227 None
 
RN113_CAEEL
WormBase»
2.6
rnf-113 Probable E3 ubiquitin-protein ligase rnf113 (EC
2.3.2.27) (RING finger protein 113 homolog)		 Caenorhabditis elegans
TI:6239 None
 
RN113_DICDI
dictyBase»
1.0
rnf113 RING finger protein 113 homolog Dictyostelium discoideum
TI:44689 None
 
Q6DRF0_DANRE
ZFIN»
1.0
rnf113a E3 ubiquitin-protein ligase RNF113A (EC 2.3.2.27) (Ring
finger protein 113A) (Zinc finger protein 183-like 1)		 Danio rerio
TI:7955 None