Standard knownness: 18.0; Custom knownness: None; Num. species: 13; Orthology database: Panther19.0; Protein members: 13
Molecular function:
positive regulation of release of cytochrome c from mitochondria2011, 2024, 2025
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress2012, 2013, 2015, 2024, 2025
positive regulation of apoptotic process2006, 2007, 2009, 2025
execution phase of apoptosis2013, 2024, 2025
release of cytochrome c from mitochondria2005, 2017, 2025
intrinsic apoptotic signaling pathway2023, 2025
positive regulation of intrinsic apoptotic signaling pathway2019, 2025
response to endoplasmic reticulum stress2012, 2025
positive regulation of protein-containing complex assembly2019, 2025
positive regulation of neuron apoptotic process2012, 2025
positive regulation of thymocyte apoptotic process2011, 2025
determination of adult lifespan2011, 2025
cellular response to hypoxia2011, 2025
apoptotic process2015, 2025
DNA damage response2013, 2025
cellular response to ionizing radiation2011, 2015
positive regulation of establishment of protein localization to mitochondrion2012
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator2006
apoptotic signaling pathway2013, 2025
negative regulation of cell growth2002
intrinsic apoptotic signaling pathway in response to DNA damage2024
intrinsic apoptotic signaling pathway by p53 class mediator2013
Cellular component: mitochondrion2005, 2015, 2024, 2025 lysosome2015, 2025 mitochondrial envelope2002
| Chordates: | 13/21 | ![]() |
| Echinoderms: | 0/0 | |
| Hemichordates: | 0/1 | |
| Annelids: | 0/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 0/3 | |
| Arthropods: | 0/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 0/1 | |
| Cnidaria: | 0/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 0/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 0/3 | |
| Excavates: | 0/4 | |
| Harosa: | 0/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Show all] | GO terms | Seq. links | Protein domain links | |||||
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BBC3B_HUMAN Ensembl» |
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BBC3 | Bcl-2-binding component 3, isoforms 3/4 (JFY-1) (p53 up-regulated modulator of apoptosis) |
Homo sapiens TI:9606 None |
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BBC3_MOUSE Ensembl» |
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Bbc3 | Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis) |
Mus musculus TI:10090 None |
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F1QKA1_DANRE ZFIN» |
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bbc3 | BCL2-binding component 3 (Bcl-2-binding component 3 isoform X1) |
Danio rerio TI:7955 None |
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BBC3_RAT RGD» |
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Bbc3 | Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis) |
Rattus norvegicus TI:10116 None |
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