Standard knownness: 17.8; Custom knownness: None; Num. species: 12; Orthology database: Panther19.0; Protein members: 12
                   Molecular function:
                   
                     positive regulation of release of cytochrome c from mitochondria2011, 2017, 2024
                   
                     intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress2012, 2013, 2015, 2017, 2024
                   
                     positive regulation of apoptotic process2007, 2009, 2024
                   
                     release of cytochrome c from mitochondria2005, 2017, 2024
                   
                     intrinsic apoptotic signaling pathway2023, 2024
                   
                     execution phase of apoptosis2013, 2017, 2024
                   
                     positive regulation of intrinsic apoptotic signaling pathway2019, 2024
                   
                     response to endoplasmic reticulum stress2012, 2024
                   
                     positive regulation of neuron apoptotic process2012, 2024
                   
                     negative regulation of growth2005, 2024
                   
                   
                      
                      
                      
                        
                          cellular response to ionizing radiation2011, 2015, 2024
                        
                          positive regulation of thymocyte apoptotic process2011, 2024
                        
                          positive regulation of protein-containing complex assembly2019, 2024
                        
                          positive regulation of lymphocyte apoptotic process2006, 2024
                        
                          positive regulation of fibroblast apoptotic process2006, 2024
                        
                          positive regulation of cysteine-type endopeptidase activity2012, 2024
                        
                          positive regulation of T cell apoptotic process2006, 2024
                        
                          lymphocyte apoptotic process2006, 2024
                        
                          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator2006, 2024
                        
                          fibroblast apoptotic process2006, 2024
                        
                          determination of adult lifespan2011, 2024
                        
                          cellular response to hypoxia2011, 2024
                        
                          activation of cysteine-type endopeptidase activity involved in apoptotic process2005, 2024
                        
                          T cell apoptotic process2006, 2024
                        
                          DNA damage response2013, 2024
                        
                          apoptotic process2015, 2024
                        
                          apoptotic signaling pathway2013
                        
                          negative regulation of cell growth2002
                        
                          intrinsic apoptotic signaling pathway in response to DNA damage2024
                        
                          intrinsic apoptotic signaling pathway by p53 class mediator2013
                        
                      
                    
                   
Cellular component: mitochondrion2005, 2015, 2023, 2024 lysosome2015 mitochondrial envelope2002
| Chordates: | 12/21 | ![]()  | 
                   
                 
| Echinoderms: | 0/0 | |
| Hemichordates: | 0/1 | |
| Annelids: | 0/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 0/3 | |
| Arthropods: | 0/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 0/1 | |
| Cnidaria: | 0/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 0/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 0/3 | |
| Excavates: | 0/4 | |
| Harosa: | 0/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 | 
Click here to switch to the previous version of the database.
| UniProt ID Organism DB»  | 
	    
        
          
            Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 
        A0A1D5QPX0_MACMU Ensembl»  | 
        
          
  | 
        
          
  | 
        BCL2 binding component 3 | 
        Macaca mulatta TI:9544 None  | 
        
          
           | 
        
          
           | 
        |||||||
| 
        A0A2I2ZTF6_GORGO Ensembl»  | 
        
          
  | 
        
          
  | 
        BCL2 binding component 3 | 
        Gorilla gorilla TI:9593 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        ||||||
| 
        A0A337SJI7_FELCA Ensembl»  | 
        
          
  | 
        
          
  | 
        BBC3 | BCL2 binding component 3 | 
        Felis catus TI:9685 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        A0A3Q1LXZ6_BOVIN Ensembl»  | 
        
          
  | 
        
          
  | 
        BBC3 | BCL2 binding component 3 | 
        Bos taurus TI:9913 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        A0A480SCP6_PIG Ensembl»  | 
        
          
  | 
        
          
  | 
        BBC3 | BCL2 binding component 3 (Bcl-2-binding component 3 isoform 4)  | 
        
        Sus scrofa TI:9823 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        A0A8I3MGC5_CANLF Ensembl»  | 
        
          
  | 
        
          
  | 
        BBC3 | BCL2 binding component 3 | 
        Canis lupus TI:9612 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        BBC3B_HUMAN Ensembl»  | 
        
          
  | 
        
          
  | 
        BBC3 | Bcl-2-binding component 3, isoforms 3/4 (JFY-1) (p53 up-regulated modulator of apoptosis)  | 
        
        Homo sapiens TI:9606 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        BBC3_MOUSE Ensembl»  | 
        
          
  | 
        
          
  | 
        Bbc3 | Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis)  | 
        
        Mus musculus TI:10090 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        BBC3_RAT RGD»  | 
        
          
  | 
        
          
  | 
        Bbc3 | Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis)  | 
        
        Rattus norvegicus TI:10116 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        F1QKA1_DANRE ZFIN»  | 
        
          
  | 
        
          
  | 
        bbc3 | BCL2 binding component 3 isoform X1 (BCL2-binding component 3)  | 
        
        Danio rerio TI:7955 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        H2QGP2_PANTR Ensembl»  | 
        
          
  | 
        
          
  | 
        BBC3 | BCL2 binding component 3 | 
        Pan troglodytes TI:9598 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        K7E5Y2_MONDO Ensembl»  | 
        
          
  | 
        
          
  | 
        BBC3 | BCL2 binding component 3 | 
        Monodelphis domestica TI:13616 None  | 
        
          
           | 
        
          
           | 
        ||||||