Standard knownness: 17.8; Custom knownness: None; Num. species: 12; Orthology database: Panther19.0; Protein members: 12
Molecular function:
positive regulation of release of cytochrome c from mitochondria2011, 2017, 2024
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress2012, 2013, 2015, 2017, 2024
positive regulation of apoptotic process2007, 2009, 2024
release of cytochrome c from mitochondria2005, 2017, 2024
intrinsic apoptotic signaling pathway2023, 2024
execution phase of apoptosis2013, 2017, 2024
positive regulation of intrinsic apoptotic signaling pathway2019, 2024
response to endoplasmic reticulum stress2012, 2024
positive regulation of neuron apoptotic process2012, 2024
negative regulation of growth2005, 2024
cellular response to ionizing radiation2011, 2015, 2024
positive regulation of thymocyte apoptotic process2011, 2024
positive regulation of protein-containing complex assembly2019, 2024
positive regulation of lymphocyte apoptotic process2006, 2024
positive regulation of fibroblast apoptotic process2006, 2024
positive regulation of cysteine-type endopeptidase activity2012, 2024
positive regulation of T cell apoptotic process2006, 2024
lymphocyte apoptotic process2006, 2024
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator2006, 2024
fibroblast apoptotic process2006, 2024
determination of adult lifespan2011, 2024
cellular response to hypoxia2011, 2024
activation of cysteine-type endopeptidase activity involved in apoptotic process2005, 2024
T cell apoptotic process2006, 2024
DNA damage response2013, 2024
apoptotic process2015, 2024
apoptotic signaling pathway2013
negative regulation of cell growth2002
intrinsic apoptotic signaling pathway in response to DNA damage2024
intrinsic apoptotic signaling pathway by p53 class mediator2013
Cellular component: mitochondrion2005, 2015, 2023, 2024 lysosome2015 mitochondrial envelope2002
Chordates: | 12/21 | |
Echinoderms: | 0/0 | |
Hemichordates: | 0/1 | |
Annelids: | 0/1 | |
Molluscs: | 0/0 | |
Bryozoans: | 0/0 | |
Platyhelminthes: | 0/0 | |
Rotifers: | 0/0 | |
Nematodes: | 0/3 | |
Arthropods: | 0/5 | |
Tardigrades: | 0/0 | |
Placozoa: | 0/1 | |
Cnidaria: | 0/1 | |
Porifera: | 0/0 | |
Choanoflagellates+: | 0/1 | |
Dikarya: | 0/14 | |
Fungi (other): | 0/1 | |
Protozoa: | 0/3 | |
Excavates: | 0/4 | |
Harosa: | 0/4 | |
Hacrobia: | 0/0 | |
Plants: | 0/39 | |
Archea: | 0/8 | |
Bacteria: | 0/35 |
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UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
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A0A2I2ZTF6_GORGO Ensembl» |
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BCL2 binding component 3 |
Gorilla gorilla TI:9593 None |
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BBC3B_HUMAN Ensembl» |
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BBC3 | Bcl-2-binding component 3, isoforms 3/4 (JFY-1) (p53 up-regulated modulator of apoptosis) |
Homo sapiens TI:9606 None |
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BBC3_MOUSE Ensembl» |
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Bbc3 | Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis) |
Mus musculus TI:10090 None |
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F1QKA1_DANRE ZFIN» |
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bbc3 | BCL2 binding component 3 isoform X1 (BCL2-binding component 3) |
Danio rerio TI:7955 None |
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H2QGP2_PANTR Ensembl» |
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BBC3 | BCL2 binding component 3 |
Pan troglodytes TI:9598 None |
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A0A337SJI7_FELCA Ensembl» |
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BBC3 | BCL2 binding component 3 |
Felis catus TI:9685 None |
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A0A480SCP6_PIG Ensembl» |
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BBC3 | BCL2 binding component 3 (Bcl-2-binding component 3 isoform 4) |
Sus scrofa TI:9823 None |
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BBC3_RAT RGD» |
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Bbc3 | Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis) |
Rattus norvegicus TI:10116 None |
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A0A1D5QPX0_MACMU Ensembl» |
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BCL2 binding component 3 |
Macaca mulatta TI:9544 None |
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A0A3Q1LXZ6_BOVIN Ensembl» |
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BBC3 | BCL2 binding component 3 |
Bos taurus TI:9913 None |
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A0A8I3MGC5_CANLF Ensembl» |
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BBC3 | BCL2 binding component 3 |
Canis lupus TI:9612 None |
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K7E5Y2_MONDO Ensembl» |
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BBC3 | BCL2 binding component 3 |
Monodelphis domestica TI:13616 None |
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