Collated Gene Ontology terms

Biological process: hydrolase activity(2008, 2022, 2024) lysophospholipase activity(2020, 2021, 2024) hydrolase activity, acting on ester bonds(2020, 2024) carboxylic ester hydrolase activity(2024) serine hydrolase activity(2016, 2021) nucleic acid binding(2024) methyltransferase activity(2024)

Molecular function: response to retinoic acid2008, 2017, 2024 secondary metabolic process2012, 2022 secondary metabolite biosynthetic process2012, 2020 apoptotic process2020, 2024 methylation2024 asperfuranone biosynthetic process2012

Cellular component: cytoplasm2008, 2018, 2023, 2024 nucleus2008, 2009, 2017, 2018, 2024 membrane2024 peroxisome2022 mitochondrion2024 cytosol2009 cell tip2009 cell division site2009

Phylogenetic distribution

Chordates: 13/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 13/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 3/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A139WJ81_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_30670 UPF0483 protein CG5412-like Protein Tribolium castaneum
TI:7070 None
 
A0A1D8PNX1_CANAL
EnsemblFungi»
0.0
CAALFM_C504350CA orf19.11403 Serine hydrolase Candida albicans
TI:5476 None
 
A0A1L8H4T1_XENLA
Xenbase»
0.0
ovca2.S Esterase OVCA2 Xenopus laevis
TI:8355 None
   
A0A2A6B5U7_PRIPA
EnsemblMetazoa»
0.0
WBGene00092440 FSH1 domain-containing protein Pristionchus pacificus
TI:54126 None
 
A0A2K3D7P5_CHLRE
EnsemblPlants»
0.0
CHLRE_11g467682v5 Serine hydrolase FSH domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2K3DZP1_CHLRE
EnsemblPlants»
0.0
CHLRE_03g201439v5 Serine hydrolase FSH domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2K3E0Y3_CHLRE
EnsemblPlants»
0.0
CHLRE_02g085600v5 Serine hydrolase FSH domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6WZA5_MARPO
EnsemblPlants»
0.0
MARPO_0046s0001 Serine hydrolase FSH domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A337SXU0_FELCA
Ensembl»
0.0
OVCA2 Esterase OVCA2 Felis catus
TI:9685 None
 
A0A644F0J1_GIAIC
EnsemblProtists»
0.0
GL50803_0014828 Alpha/beta hydrolase Giardia intestinalis
TI:5741 None
 
A0A7M7T131_STRPU
EnsemblMetazoa»
0.0
Serine hydrolase FSH domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A8J0UDZ1_XENLA
Xenbase»
0.0
ovca2.L Esterase OVCA2 Xenopus laevis
TI:8355 None
   
A0A8V1ANK8_CHICK
Ensembl»
0.0
Esterase OVCA2 Gallus gallus
TI:9031 None
   
A0A9J7MA56_BRAFL
CTD»
0.0
LOC118429138 Esterase OVCA2 Branchiostoma floridae
TI:7739 None
   
A0A9K3IJX3_HELAN
EnsemblPlants»
0.0
HanXRQr2_Chr07g0290851 Serine hydrolase FSH, alpha/Beta hydrolase Helianthus annuus
TI:4232 None
 
A0D1W9_PARTE
EnsemblProtists»
0.0
GSPATT00012561001 Chromosome undetermined scaffold_34,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0D1X0_PARTE
EnsemblProtists»
0.0
GSPATT00012562001 Chromosome undetermined scaffold_34,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0D5Q5_PARTE
EnsemblProtists»
0.0
GSPATT00013802001 Chromosome undetermined scaffold_39,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0DEB8_PARTE
EnsemblProtists»
0.0
GSPATT00016211001 Chromosome undetermined scaffold_48,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0EA70_PARTE
EnsemblProtists»
0.0
GSPATT00024919001 Chromosome undetermined scaffold_85,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A2FNB1_TRIV3
VEuPathDB»
0.0
TVAG_427290 Serine hydrolase domain-containing protein Trichomonas vaginalis
TI:5722 None
 
A7E524_SCLS1
EnsemblFungi»
0.0
SS1G_00396 Serine hydrolase FSH domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A7E9L9_SCLS1
EnsemblFungi»
0.0
SS1G_01999 Serine hydrolase FSH domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A7EHB8_SCLS1
EnsemblFungi»
0.0
SS1G_04710 Serine hydrolase FSH domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A7EKE2_SCLS1
EnsemblFungi»
0.0
SS1G_05789 Serine hydrolase FSH domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A7EVV3_SCLS1
EnsemblFungi»
0.0
SS1G_09462 Serine hydrolase FSH domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A7F7Q9_SCLS1
VEuPathDB»
0.0
SS1G_13639 Serine hydrolase FSH domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A7SDP4_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g210684 Serine hydrolase FSH domain-containing protein Nematostella vectensis
TI:45351 None
 
AFOC_EMENI
EnsemblFungi»
0.0
afoC Probable esterase afoC (EC
3.1.2.-) (Asperfuranone biosynthesis protein B)		 Emericella nidulans
TI:162425 None
 
ALNB_EMENI
EnsemblFungi»
0.0
alnB Esterase alnB (EC 3.1.2.-)
(Asperlin biosynthesis cluster protein B)		 Emericella nidulans
TI:162425 None
 
B3RJ41_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_52561 Serine hydrolase FSH domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B6K2W1_SCHJY
EnsemblFungi»
0.0
SJAG_03760 Serine hydrolase Schizosaccharomyces japonicus
TI:4897 None
 
B7Q352_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW020303 Serine hydrolase FSH domain-containing protein Ixodes scapularis
TI:6945 None
 
B8BYE8_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_261864 Serine hydrolase FSH domain-containing protein Thalassiosira pseudonana
TI:35128 None
 
B8CBP0_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_24702 Serine hydrolase FSH domain-containing protein Thalassiosira pseudonana
TI:35128 None
 
C8V9Z4_EMENI
EnsemblFungi»
0.0
ANIA_11117 DUF341 family oxidoreductase,
putative (AFU_orthologue AFUA_3G01420)		 Emericella nidulans
TI:162425 None
 
C8VC20_EMENI
EnsemblFungi»
0.0
ANIA_10993 EF-hand calcium-binding domain
protein, putative (AFU_orthologue AFUA_2G01310)		 Emericella nidulans
TI:162425 None
 
C8VL88_EMENI
EnsemblFungi»
0.0
ANIA_11156 Serine hydrolase FSH domain-containing protein Emericella nidulans
TI:162425 None
 
DBAE_EMENI
EnsemblFungi»
0.0
dbaE Esterase dbaE (EC 3.1.2.-) (Derivative
of benzaldehyde biosynthesis cluster protein E)		 Emericella nidulans
TI:162425 None
 
E3L512_PUCGT
EnsemblFungi»
0.0
PGTG_17691 Serine hydrolase FSH domain-containing protein Puccinia graminis
TI:5297 None
 
E9FVY6_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_220828 Serine hydrolase FSH domain-containing protein Daphnia pulex
TI:6669 None
 
F0ZPI1_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_98320 Serine hydrolase FSH domain-containing protein Dictyostelium purpureum
TI:5786 None
 
F4NZ31_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_23456 Serine hydrolase FSH domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F6QJ19_HORSE
Ensembl»
0.0
OVCA2 Esterase OVCA2 Equus caballus
TI:9796 None
   
F7GI08_MONDO
Ensembl»
0.0
OVCA2 Esterase OVCA2 Monodelphis domestica
TI:13616 None
   
FSH1_YEAST
SGD»
2.9
FSH1 Family of serine hydrolases 1 (EC 3.1.-.-) Saccharomyces cerevisiae
TI:4932 None
 
FSH2_YEAST
SGD»
0.5
FSH2 Family of serine hydrolases 2 (EC 3.1.-.-) Saccharomyces cerevisiae
TI:4932 None
 
FSH3_YEAST
SGD»
0.5
FSH3 Family of serine hydrolases 3 (EC 3.1.-.-) Saccharomyces cerevisiae
TI:4932 None
 
G3R1S1_GORGO
Ensembl»
0.0
Esterase OVCA2 Gorilla gorilla
TI:9593 None
 
H2LDW9_ORYLA
Ensembl»
0.0
ovca2 Esterase OVCA2 Oryzias latipes
TI:8090 None
   
H3GEI5_PHYRM
EnsemblProtists»
0.0
Serine hydrolase FSH domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3GGX6_PHYRM
EnsemblProtists»
0.0
Serine hydrolase FSH domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3GMP9_PHYRM
EnsemblProtists»
0.0
Serine hydrolase FSH domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3GQU3_PHYRM
EnsemblProtists»
0.0
Serine hydrolase FSH domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3GQU4_PHYRM
EnsemblProtists»
0.0
Serine hydrolase FSH domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3GQU7_PHYRM
EnsemblProtists»
0.0
Serine hydrolase FSH domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3GQU8_PHYRM
EnsemblProtists»
0.0
Serine hydrolase FSH domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3H609_PHYRM
EnsemblProtists»
0.0
Serine hydrolase FSH domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3HC90_PHYRM
EnsemblProtists»
0.0
Serine hydrolase FSH domain-containing protein Phytophthora ramorum
TI:164328 None
 
INPF_EMENI
EnsemblFungi»
0.0
inpF Esterase inpF (EC 3.1.2.-) (Fellutamide B biosynthesis
cluster protein F) (Inp cluster protein F)		 Emericella nidulans
TI:162425 None
 
LOVG_ANOGA
EnsemblMetazoa»
0.0
AGAP003155 Esterase AGAP003155 (EC 3.1.2.-) Anopheles gambiae
TI:7165 None
 
LOVG_CAEBR
WormBase»
0.0
CBG03338 Esterase CBG03338 (EC 3.1.2.-) Caenorhabditis briggsae
TI:6238 None
 
LOVG_CAEEL
WormBase»
1.0
C25G4.2 Esterase C25G4.2 (EC 3.1.2.-) Caenorhabditis elegans
TI:6239 None
 
LOVG_DROME
FlyBase»
2.0
CG5412 Esterase CG5412 (EC 3.1.2.-) Drosophila melanogaster
TI:7227 None
 
OVCA2_BOVIN
Ensembl»
0.0
OVCA2 Esterase OVCA2 (EC 3.1.2.-) (Ovarian
cancer-associated gene 2 protein homolog)		 Bos taurus
TI:9913 None
 
OVCA2_DANRE
ZFIN»
1.0
ovca2 Esterase OVCA2 (EC 3.1.2.-) (Ovarian
cancer-associated gene 2 protein homolog)		 Danio rerio
TI:7955 None
 
OVCA2_HUMAN
Ensembl»
2.4
OVCA2 Esterase OVCA2 (EC 3.1.2.-)
(Ovarian cancer-associated gene 2 protein)		 Homo sapiens
TI:9606 None
 
OVCA2_MOUSE
Ensembl»
0.0
Ovca2 Esterase OVCA2 (EC 3.1.2.-) (Ovarian
cancer-associated gene 2 protein homolog)		 Mus musculus
TI:10090 None
 
OVCA2_XENTR
Xenbase»
0.0
ovca2 Esterase OVCA2 (EC 3.1.2.-) (Ovarian
cancer-associated gene 2 protein homolog)		 Xenopus tropicalis
TI:8364 None
 
Q4WB35_ASPFU
EnsemblFungi»
0.0
AFUA_8G00910 Serine hydrolase FSH domain-containing protein Aspergillus fumigatus
TI:746128 None
 
Q4WDP5_ASPFU
EnsemblFungi»
0.0
AFUA_5G00200 Serine hydrolase FSH domain-containing protein Aspergillus fumigatus
TI:746128 None
 
Q4WFQ2_ASPFU
EnsemblFungi»
0.0
AFUA_3G01420 DUF341 family oxidoreductase, putative Aspergillus fumigatus
TI:746128 None
 
Q4WIM6_ASPFU
EnsemblFungi»
0.0
AFUA_2G01310 EF-hand calcium-binding domain protein, putative Aspergillus fumigatus
TI:746128 None
 
Q4WIM7_ASPFU
EnsemblFungi»
0.0
AFUA_2G01300 Serine hydrolase FSH domain-containing protein Aspergillus fumigatus
TI:746128 None
 
Q4WR32_ASPFU
EnsemblFungi»
0.0
AFUA_1G17720 Oxidoreductase, putative Aspergillus fumigatus
TI:746128 None
 
Q4WWP7_ASPFU
EnsemblFungi»
0.0
AFUA_3G06620 Dihydrofolate reductase Aspergillus fumigatus
TI:746128 None
 
Q55D01_DICDI
dictyBase»
0.5
DDB_G0270972 DUF341 family protein Dictyostelium discoideum
TI:44689 None
 
Q5ADX4_CANAL
EnsemblFungi»
0.0
CAALFM_C307700WA orf19.14009 Serine hydrolase Candida albicans
TI:5476 None
 
Q5ARC1_EMENI
EnsemblFungi»
0.0
ANIA_09159 Serine hydrolase FSH domain-containing protein Emericella nidulans
TI:162425 None
 
Q5AY41_EMENI
EnsemblFungi»
0.0
ANIA_06789 Serine hydrolase FSH domain-containing protein Emericella nidulans
TI:162425 None
 
Q5B3V4_EMENI
EnsemblFungi»
0.0
ANIA_04776 Dihydrofolate reductase
(AFU_orthologue AFUA_3G06620)		 Emericella nidulans
TI:162425 None
 
Q5BBP9_EMENI
EnsemblFungi»
0.0
ANIA_02031 Serine hydrolase FSH domain-containing protein Emericella nidulans
TI:162425 None
 
Q5BG01_EMENI
EnsemblFungi»
0.0
ANIA_00529 Serine hydrolase FSH domain-containing protein Emericella nidulans
TI:162425 None
 
Q5KJH3_CRYNJ
EnsemblFungi»
0.0
CNC06550 Expressed protein Cryptococcus neoformans
TI:5207 None
 
Q5KJH4_CRYNJ
EnsemblFungi»
0.0
CNC06540 Serine hydrolase FSH domain-containing protein Cryptococcus neoformans
TI:5207 None
 
Q6C8U4_YARLI
EnsemblFungi»
0.0
YALI0_D16940g YALI0D16940p Yarrowia lipolytica
TI:4952 None
 
Q756B1_ASHGO
EnsemblFungi»
0.0
AGOS_AER356C AER356Cp Ashbya gossypii
TI:33169 None
 
Q75C41_ASHGO
EnsemblFungi»
0.0
AGOS_ACR076C ACR076Cp Ashbya gossypii
TI:33169 None
 
Q7RX12_NEUCR
EnsemblFungi»
0.0
NCU05012 Serine hydrolase FSH domain-containing protein Neurospora crassa
TI:5141 None
 
Q7S2E5_NEUCR
EnsemblFungi»
0.0
NCU06012 Serine hydrolase FSH domain-containing protein Neurospora crassa
TI:5141 None
 
Q7S3L0_NEUCR
EnsemblFungi»
0.0
NCU08233 Serine hydrolase FSH domain-containing protein Neurospora crassa
TI:5141 None
 
Q7S865_NEUCR
EnsemblFungi»
0.0
NCU08691 EF-hand calcium-binding
domain-containing protein		 Neurospora crassa
TI:5141 None
 
Q7SGJ0_NEUCR
EnsemblFungi»
0.0
NCU08094 Dihydrofolate reductase Neurospora crassa
TI:5141 None
 
YF36_SCHPO
PomBase»
1.0
SPAC22A12.06c Uncharacterized hydrolase
C22A12.06c (EC 3.1.-.-)		 Schizosaccharomyces pombe
TI:4896 None