Collated Gene Ontology terms

Biological process: sepiapterin reductase activity(2003, 2005, 2009, 2010, 2017, 2024) oxidoreductase activity(2024) protein homodimerization activity(2009) benzil reductase [(S)-benzoin-forming] activity(2024) aldo-keto reductase (NADP) activity(2006) NADP binding(2006)

Molecular function: tetrahydrobiopterin biosynthetic process2005, 2006, 2007, 2017, 2024 nitric oxide biosynthetic process2006, 2024 voluntary musculoskeletal movement2008 tetrahydrobiopterin metabolic process2008 serotonin metabolic process2008 response to oxidative stress2015, 2024 regulation of multicellular organism growth2008 pteridine-containing compound biosynthetic process2006, 2024 pteridine metabolic process2008 norepinephrine metabolic process2008
dopamine metabolic process2008 cell morphogenesis involved in neuron differentiation2008 L-phenylalanine metabolic process2008 response to Gram-negative bacterium2020 positive regulation of cell population proliferation2007

Cellular component: cytoplasm2024 cytosol2013, 2023, 2024 nucleoplasm2023, 2024 mitochondrion2009, 2024 extracellular exosome2014

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 2/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q9W3F1_DROME
FlyBase»
1.0
144701_at RE21057p Drosophila melanogaster
TI:7227 None
 
B3DJY2_DANRE
ZFIN»
1.0
LOC795445 Sepiapterin reductase (EC 1.1.1.153) Danio rerio
TI:7955 None
 
A0A8V0ZD26_CHICK
Ensembl»
0.0
SPR Sepiapterin reductase (EC 1.1.1.153) Gallus gallus
TI:9031 None
   
SPRE_HUMAN
Ensembl»
5.9
SPR Sepiapterin reductase (SPR) (EC 1.1.1.153) Homo sapiens
TI:9606 None
 
SPRE_MOUSE
AG»
8.5
Spr Sepiapterin reductase (SPR) (EC 1.1.1.153) Mus musculus
TI:10090 None
 
SPRE_RAT
RGD»
10.7
Spr Sepiapterin reductase (SPR) (EC 1.1.1.153) Rattus norvegicus
TI:10116 None
 
D3ZT59_RAT
RGD»
1.0
Spr-ps1 Sepiapterin reductase (EC 1.1.1.153) Rattus norvegicus
TI:10116 None
   
O76752_DROME
FlyBase»
1.8
Sptr Sepiapterin reductase (EC 1.1.1.153) Drosophila melanogaster
TI:7227 None
 
F1QWX4_DANRE
ZFIN»
1.0
fj86h06 Sepiapterin reductase (EC 1.1.1.153) Danio rerio
TI:7955 None
 
SPRE_DICDI
dictyBase»
5.2
sprA Sepiapterin reductase (SPR) (SR) (EC 1.1.1.153) Dictyostelium discoideum
TI:44689 None