Collated Gene Ontology terms

Biological process: riboflavin reductase (NADPH) activity(2010, 2018, 2022, 2023, 2025) biliverdin reductase [NAD(P)H] activity(2003, 2010, 2018, 2022, 2023, 2025) peptidyl-cysteine S-nitrosylase activity(2023, 2025) catalytic activity(2025) oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(2022, 2025) oxidoreductase activity(2025) transferase activity(2025) FMN reductase (NADPH) activity(2025) FMN reductase (NADH) activity(2025)

Molecular function: negative regulation of insulin receptor signaling pathway2023, 2025 megakaryocyte differentiation2023, 2025 heme catabolic process2010, 2023, 2025 reactive oxygen species biosynthetic process2025 membrane lipid catabolic process2025 homeostasis of number of cells2025 hemopoiesis2025 erythrocyte differentiation2025 cellular response to stress2025 cell fate specification2025
bone marrow development2025 animal organ morphogenesis2025 sterigmatocystin biosynthetic process2024 mating2025 insulin receptor signaling pathway2025

Cellular component: cytosol2010, 2013, 2025 cytoplasm2023, 2025 terminal bouton2016, 2022, 2025 membrane2025 plasma membrane2025 nucleoplasm2025 extracellular exosome2013

Phylogenetic distribution

Chordates: 19/21 
Echinoderms: 0/0 
Hemichordates: 0/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 7/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 1/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 10/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 5 10 15 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
BLVRB_HUMAN
Ensembl»
7.5
BLVRB Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (EC 1.3.1.-) (Biliverdin-IX beta-reductase)
(Green heme-binding protein) (GHBP) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR) (S-nitroso-CoA-assisted nitrosyltransferase) (SNO-CoA-assisted nitrosyltransferase) (EC 2.6.99.-)		 Homo sapiens
TI:9606 None
 
Q9VH72_DROME
FlyBase»
2.8
BVR TA01656p1 (Uncharacterized protein, isoform A) (Uncharacterized
protein, isoform B (EC 1.3.1.24, EC 1.5.1.30))		 Drosophila melanogaster
TI:7227 None
 
BLVRB_MOUSE
Ensembl»
16.6
Blvrb Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (Biliverdin-IX beta-reductase)
(EC 1.3.1.-) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR) (S-nitroso-CoA-assisted nitrosyltransferase) (SNO-CoA-assisted nitrosyltransferase) (EC 2.6.99.-)		 Mus musculus
TI:10090 None
 
A0A8I5ZUN1_RAT
RGD»
7.5
Blvrb Flavin reductase (NADPH) (EC 1.5.1.30) (Biliverdin reductase B)
(Biliverdin-IX beta-reductase) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (S-nitroso-CoA-assisted nitrosyltransferase)		 Rattus norvegicus
TI:10116 None
   
A0A8I6A3K7_RAT
RGD»
1.0
ENSRNOG00000064875 NAD(P)-binding domain-containing protein Rattus norvegicus
TI:10116 None
   
A0A8M1N0W6_DANRE
ZFIN»
0.0
blvrb Flavin reductase (NADPH) (EC 1.3.1.24) Danio rerio
TI:7955 None