Collated Gene Ontology terms

Biological process: riboflavin reductase (NADPH) activity(2010, 2018, 2022, 2023, 2024) biliverdin reductase (NAD(P)+) activity(2003, 2010, 2018, 2022, 2023, 2024) oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(2022) peptidyl-cysteine S-nitrosylase activity(2023, 2024) oxidoreductase activity(2024) transferase activity(2024) FMN reductase (NADPH) activity(2024) FMN reductase (NADH) activity(2024) FMN reductase (NAD(P)H) activity(2024) riboflavin reductase (NAD(P)H) activity(2024)

Molecular function: negative regulation of insulin receptor signaling pathway2023, 2024 megakaryocyte differentiation2023, 2024 heme catabolic process2010, 2023, 2024 sterigmatocystin biosynthetic process2024 sexual reproduction2012

Cellular component: cytoplasm2023, 2024 cytosol2010, 2013, 2023, 2024 plasma membrane2023, 2024 nucleoplasm2023, 2024 intracellular membrane-bounded organelle2023, 2024 terminal bouton2016 membrane2024 extracellular exosome2013

Phylogenetic distribution

Chordates: 19/21 
Echinoderms: 0/0 
Hemichordates: 0/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 6/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 1/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 10/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
BLVRB_HUMAN
Ensembl»
7.5
BLVRB Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (EC
1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR)		 Homo sapiens
TI:9606 None
 
BLVRB_MOUSE
Ensembl»
4.1
Blvrb Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B)
(BVR-B) (EC 1.3.1.24) (Biliverdin-IX beta-reductase) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR)		 Mus musculus
TI:10090 None
 
A0A8I6AHQ8_RAT
RGD»
4.0
Blvrb Biliverdin reductase B Rattus norvegicus
TI:10116 None
   
Q9VH72_DROME
FlyBase»
2.8
BVR TA01656p1 (Uncharacterized protein, isoform A (EC 1.3.1.24,
EC 1.5.1.30, EC 1.5.1.41)) (Uncharacterized protein, isoform B)		 Drosophila melanogaster
TI:7227 None
 
Q6DGA0_DANRE
ZFIN»
1.0
zgc:91854 Flavin reductase (NADPH) (EC
1.3.1.24) (Zgc:91854) (Zgc:91854 protein)		 Danio rerio
TI:7955 None
 
A0A5F5XZZ9_FELCA
Ensembl»
0.0
BLVRB Biliverdin reductase B Felis catus
TI:9685 None
 
A0A6I8PLQ3_ORNAN
Ensembl»
0.0
NAD(P)-binding domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8SEW4_XENTR
Xenbase»
0.0
blvrb Biliverdin reductase B (Flavin
reductase (NADPH) isoform X1)		 Xenopus tropicalis
TI:8364 None 		     
A0A803SU05_ANOCA
Ensembl»
0.0
blvrb Biliverdin reductase B Anolis carolinensis
TI:28377 None 		     
A0A8I3MIS0_CANLF
Ensembl»
0.0
BLVRB Biliverdin reductase B Canis lupus
TI:9612 None
   
A0A8I6A3K7_RAT
RGD»
0.0
ENSRNOG00000064875 NAD(P)-binding domain-containing protein Rattus norvegicus
TI:10116 None 		     
A0A8J1IPN3_XENTR
Xenbase»
0.0
LOC116406791 LOW QUALITY PROTEIN: flavin reductase (NADPH) Xenopus tropicalis
TI:8364 None 		     
A2EA58_TRIV3
VEuPathDB»
0.0
TVAG_484150 NAD(P)-binding domain-containing protein Trichomonas vaginalis
TI:5722 None
 
A2EJQ2_TRIV3
VEuPathDB»
0.0
TVAG_342900 Isoflavone reductase, putative Trichomonas vaginalis
TI:5722 None
 
A2G6A3_TRIV3
VEuPathDB»
0.0
TVAG_169470 Oxidoreductase, putative Trichomonas vaginalis
TI:5722 None 		 
 
A5HYH9_CLOBH
Ensembl»
0.0
CBO0286 NAD(P)-binding domain-containing protein Clostridium botulinum
TI:1491 None
 
A7E952_SCLS1
EnsemblFungi»
0.0
SS1G_01832 NAD(P)-binding domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A7ETA8_SCLS1
EnsemblFungi»
0.0
SS1G_08563 NAD(P)-binding domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
B7PJY6_IXOSC
EnsemblMetazoa»
0.0
8030073 Flavonol reductase/cinnamoyl-CoA reductase,
putative (EC 1.5.1.30)		 Ixodes scapularis
TI:6945 None
 
BLVRB_BOVIN
Ensembl»
0.0
BLVRB Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (EC
1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR)		 Bos taurus
TI:9913 None
 
C8VDD4_EMENI
EnsemblFungi»
0.0
ANIA_10896 NAD(P)-binding domain-containing protein Emericella nidulans
TI:162425 None
 
D6WR30_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_09981 Flavin reductase (NADPH)-like Protein Tribolium castaneum
TI:7070 None
 
E9G6Z2_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_230602 NAD(P)-binding domain-containing protein Daphnia pulex
TI:6669 None
 
F4PF00_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_92947 NAD(P)-binding domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F6WNP9_CIOIN
Ensembl»
0.0
NAD(P)-binding domain-containing protein Ciona intestinalis
TI:7719 None
 
F7D2D9_HORSE
Ensembl»
0.0
BLVRB Biliverdin reductase B Equus caballus
TI:9796 None
   
F7EVI4_MONDO
Ensembl»
0.0
BLVRB Biliverdin reductase B Monodelphis domestica
TI:13616 None
   
G3R9B2_GORGO
Ensembl»
0.0
BLVRB Biliverdin reductase B Gorilla gorilla
TI:9593 None
 
G7NLH4_MACMU
Ensembl»
0.0
BLVRB Biliverdin reductase B (Flavin
reductase) (Flavin reductase (NADPH))		 Macaca mulatta
TI:9544 None
 
H2QGC7_PANTR
Ensembl»
0.0
BLVRB Biliverdin reductase B (Biliverdin
reductase B (Flavin reductase (NADPH)))		 Pan troglodytes
TI:9598 None
 
I3LQH7_PIG
Ensembl»
0.0
BLVRB Biliverdin reductase B
(Flavin reductase (NADPH))		 Sus scrofa
TI:9823 None
 
Q4WT01_ASPFU
EnsemblFungi»
0.0
AFUA_1G11040 NAD(P)-binding domain-containing protein Aspergillus fumigatus
TI:746128 None
 
Q5K9Z2_CRYNJ
EnsemblFungi»
0.0
CNK00190 NAD(P)-binding domain-containing protein Cryptococcus neoformans
TI:5207 None
 
Q6GQF4_XENLA
Xenbase»
0.0
blvrb.L Biliverdin reductase B
L homeolog (MGC80107 protein)		 Xenopus laevis
TI:8355 None
 
Q7PXB6_ANOGA
EnsemblMetazoa»
0.0
1281857 AGAP001321-PA Anopheles gambiae
TI:7165 None
 
Q7SA22_NEUCR
EnsemblFungi»
0.0
NCU07341 NAD(P)-binding domain-containing protein Neurospora crassa
TI:5141 None
 
Q815S8_BACCR
EnsemblBacteria»
0.0
BC_5054 NAD-dependent dehydrogenase Bacillus cereus
TI:1396 None
 
Q81EE0_BACCR
EnsemblBacteria»
0.0
BC_2042 NAD-dependent dehydrogenase Bacillus cereus
TI:1396 None
 
Q89I04_BRADU
EnsemblBacteria»
0.0
bll5835 Bll5835 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q89Z24_BACTN
EnsemblBacteria»
0.0
BT_4553 NAD-dependent epimerase/dehydratase Bacteroides thetaiotaomicron
TI:818 None
 
Q8DNX9_STRR6
EnsemblBacteria»
0.0
spr1468 NAD(P)-binding domain-containing protein Streptococcus pneumoniae
TI:1313 None
 
Q8EIR7_SHEON
EnsemblPlants»
0.0
SO_0768 NAD dependent
epimerase/dehydratase family protein		 Shewanella oneidensis
TI:70863 None
 
Q8Y8U8_LISMO
EnsemblBacteria»
0.0
lmo0794 Lmo0794 protein Listeria monocytogenes
TI:1639 None
 
Q9I5I8_PSEAE
EnsemblBacteria»
0.0
PA0741 NAD(P)-binding domain-containing protein Pseudomonas aeruginosa
TI:287 None
 
Q9KKP8_VIBCH
EnsemblBacteria»
0.0
VC_A1054 NAD(P)-binding domain-containing protein Vibrio cholerae
TI:666 None
 
STCO_EMENI
EnsemblFungi»
0.0
stcO Averufin oxidase stcO (EC 1.-.-.-)
(Sterigmatocystin biosynthesis cluster protein O)		 Emericella nidulans
TI:162425 None
 
W5NBC4_LEPOC
Ensembl»
0.0
Biliverdin reductase B Lepisosteus oculatus
TI:7918 None
 
YHEG_BACSU
EnsemblBacteria»
0.0
yheG Uncharacterized protein YheG Bacillus subtilis
TI:1423 None
 
YWNB_BACSU
EnsemblBacteria»
0.0
ywnB Uncharacterized protein YwnB Bacillus subtilis
TI:1423 None