Collated Gene Ontology terms

Biological process: nucleoside diphosphate kinase activity(2024) microtubule binding(2015, 2022, 2024) 3'-5' exonuclease activity(2023, 2024) hydrolase activity(2024) dynein complex binding(2024) oxysterol binding(2024) kinase activity(2024) G protein-coupled receptor activity(2024)

Molecular function: UTP biosynthetic process2024 GTP biosynthetic process2024 CTP biosynthetic process2024 flagellated sperm motility2015, 2022, 2024 cilium assembly2015, 2022, 2024 cellular response to reactive oxygen species2015, 2024 spermatogenesis2024 cell differentiation2024 spermatid development2005 phosphorylation2024
cell redox homeostasis2022 G protein-coupled receptor signaling pathway2024

Cellular component: sperm principal piece2015, 2020, 2022, 2024 cytoplasm2020, 2024 axoneme2020, 2022, 2024 sperm cytoplasmic droplet2015, 2024 nucleus2020, 2024 sperm midpiece2020, 2024 outer dynein arm2015, 2024 cytosol2011, 2023, 2024 nuclear speck2023, 2024 dynein axonemal particle2021, 2024
cytoskeleton2024 cell projection2024 sperm fibrous sheath2015 membrane2024 ruffle2024 plasma membrane2024 mitochondrion2023 lamellipodium2024

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 1/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
TXND3_HUMAN
Ensembl»
3.9
NME8 Thioredoxin domain-containing protein 3 (NM23-H8) (NME/NM23
family member 8) (Spermatid-specific thioredoxin-2) (Sptrx-2)		 Homo sapiens
TI:9606 None
 
TXND3_RAT
RGD»
5.1
Nme8 Thioredoxin domain-containing protein 3 (NME/NM23
family member 8) (Spermatid-specific thioredoxin-2) (Sptrx-2)		 Rattus norvegicus
TI:10116 None
 
A0A1D5PUV4_CHICK
Ensembl»
1.5
NME8 NME/NM23 family member 8 Gallus gallus
TI:9031 None
   
TXND3_MOUSE
Ensembl»
2.1
Nme8 Thioredoxin domain-containing protein 3 (NME/NM23
family member 8) (Spermatid-specific thioredoxin-2) (Sptrx-2)		 Mus musculus
TI:10090 None
 
A0A2J8PZ64_PANTR
Ensembl»
0.0
NME8 NME/NM23 family member 8 Pan troglodytes
TI:9598 None
 
F1SAE4_PIG
Ensembl»
0.0
NME8 NME/NM23 family member 8 Sus scrofa
TI:9823 None
   
F6QHM5_MACMU
Ensembl»
0.0
NME8 NME/NM23 family member 8 Macaca mulatta
TI:9544 None
   
G3QWW2_GORGO
Ensembl»
0.0
NME8 NME/NM23 family member 8 Gorilla gorilla
TI:9593 None
 
M3WHE4_FELCA
Ensembl»
0.0
NME8 NME/NM23 family member 8 Felis catus
TI:9685 None
 
F7A1E6_HORSE
Ensembl»
0.0
NME8 NME/NM23 family member 8 Equus caballus
TI:9796 None
   
A0A3Q2HXC1_HORSE
Ensembl»
0.0
Nucleoside diphosphate
kinase-like domain-containing protein		 Equus caballus
TI:9796 None
   
TXND6_HUMAN
Ensembl»
0.0
NME9 Thioredoxin domain-containing protein 6
(Thioredoxin-like protein 2) (Txl-2)		 Homo sapiens
TI:9606 None
 
TXND6_MOUSE
Ensembl»
0.0
Nme9 Thioredoxin domain-containing protein 6
(Thioredoxin-like protein 2) (Txl-2)		 Mus musculus
TI:10090 None
 
TXND6_XENLA
Xenbase»
0.0
nme9 Thioredoxin domain-containing protein 6
(Thioredoxin-like protein 2) (Txl-2)		 Xenopus laevis
TI:8355 None
 
A8BLA6_GIAIC
EnsemblProtists»
0.0
GL50803_0014135 GL50803_14135 Nucleoside diphosphate kinase (EC 2.7.4.6) Giardia intestinalis
TI:5741 None
 
H2MPF9_ORYLA
Ensembl»
0.0
LOC101170553 Nucleoside diphosphate kinase B Oryzias latipes
TI:8090 None
   
A0A8I3PJ76_CANLF
Ensembl»
0.0
NME8 Uncharacterized protein Canis lupus
TI:9612 None
   
TXND3_CIOIN
Ensembl»
0.0
CiIC3 Thioredoxin domain-containing protein 3
homolog (Dynein intermediate chain 3)		 Ciona intestinalis
TI:7719 None
 
A0A2I2YW59_GORGO
Ensembl»
0.0
NME9 NME/NM23 family member 9 Gorilla gorilla
TI:9593 None
 
A0A2I3SG45_PANTR
Ensembl»
0.0
NME9 NME/NM23 family member 9 Pan troglodytes
TI:9598 None
 
A0A3Q2I0L6_HORSE
Ensembl»
0.0
NME9 NME/NM23 family member 9 Equus caballus
TI:9796 None
   
A0A7M7N220_STRPU
EnsemblMetazoa»
0.0
Nucleoside diphosphate
kinase-like domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7SUG1_STRPU
EnsemblMetazoa»
0.0
Nucleoside diphosphate
kinase-like domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3PRC2_CANLF
Ensembl»
0.0
NME9 NME/NM23 family member 9 Canis lupus
TI:9612 None
   
A0A8M9Q4G2_DANRE
CTD»
0.0
nme8 Thioredoxin domain-containing protein
6 isoform X1		 Danio rerio
TI:7955 None
   
A0A8W4F8Y8_PIG
Ensembl»
0.0
NME9 NME/NM23 family member 9 Sus scrofa
TI:9823 None
   
A0A9J7HQM9_BRAFL
CTD»
0.0
LOC118407607 nucleoside-diphosphate kinase (EC 2.7.4.6) Branchiostoma floridae
TI:7739 None
   
A7S268_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g101462 Nucleoside diphosphate
kinase-like domain-containing protein		 Nematostella vectensis
TI:45351 None
 
A9V116_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_32671 Nucleoside diphosphate
kinase-like domain-containing protein		 Monosiga brevicollis
TI:81824 None
 
F4P4A3_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_35212 Nucleoside diphosphate kinase Batrachochytrium dendrobatidis
TI:109871 None
 
F6TSD9_MACMU
Ensembl»
0.0
NME9 NME/NM23 family member 9 Macaca mulatta
TI:9544 None
   
F7EXL8_ORNAN
Ensembl»
0.0
NME9 NME/NM23 family member 9 Ornithorhynchus anatinus
TI:9258 None
   
F7FMF8_ORNAN
Ensembl»
0.0
Nucleoside diphosphate
kinase-like domain-containing protein		 Ornithorhynchus anatinus
TI:9258 None
   
F7FRS4_MONDO
Ensembl»
0.0
NME9 NME/NM23 family member 9 Monodelphis domestica
TI:13616 None
   
M3X2W4_FELCA
Ensembl»
0.0
NME9 NME/NM23 family member 9 Felis catus
TI:9685 None
 
W5MTQ7_LEPOC
Ensembl»
0.0
NME/NM23 family member 8 Lepisosteus oculatus
TI:7918 None
 
W5N0B4_LEPOC
Ensembl»
0.0
Nucleoside diphosphate
kinase-like domain-containing protein		 Lepisosteus oculatus
TI:7918 None
 
A0A139WH38_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_33152 Thioredoxin domain-containing protein Tribolium castaneum
TI:7070 None
 
A0A8J0QM05_XENTR
Xenbase»
0.0
c16orf71 Dynein axonemal assembly factor
8 (Dynein axonemal-associated protein 1)		 Xenopus tropicalis
TI:8364 None
   
A0A8M2BBI0_DANRE
CTD»
0.0
LOC101882899 Dynein axonemal assembly factor
8 (Dynein axonemal-associated protein 1)		 Danio rerio
TI:7955 None
   
Q8IKL4_PLAF7
EnsemblProtists»
0.0
tlp1 Thioredoxin-like protein
(Thioredoxin-like protein 1)		 Plasmodium falciparum
TI:5833 None
 
A0A1S4H9Y2_ANOGA
EnsemblMetazoa»
0.0
Thioredoxin domain-containing protein 3 Anopheles gambiae
TI:7165 None 		 
 
A0A1Y1IDC9_KLENI
EnsemblPlants»
0.0
KFL_003070150 Thioredoxin domain-containing protein Klebsormidium nitens
TI:105231 None 		 
 
A0A5F8G8L3_MONDO
Ensembl»
0.0
Thioredoxin domain-containing protein Monodelphis domestica
TI:13616 None 		     
A0A803SVM5_ANOCA
Ensembl»
0.0
Thioredoxin domain-containing protein Anolis carolinensis
TI:28377 None 		     
A0A8V0ZXR7_CHICK
Ensembl»
0.0
Thioredoxin domain-containing protein Gallus gallus
TI:9031 None 		     
A8BXI4_GIAIC
EnsemblProtists»
0.0
GL50803_0015460 GL50803_15460 Dynein-like protein Giardia intestinalis
TI:5741 None 		 
 
A8J594_CHLRE
EnsemblPlants»
0.0
CHLRE_12g528850v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None 		 
 
A8JDC5_CHLRE
EnsemblPlants»
0.0
CHLRE_17g714250v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None 		 
 
B3RIU9_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_51377 Nucleoside diphosphate
kinase-like domain-containing protein		 Trichoplax adhaerens
TI:10228 None 		 
 
B3RRV0_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_22954 Thioredoxin domain-containing protein Trichoplax adhaerens
TI:10228 None 		 
 
D3ZGC8_RAT
RGD»
0.0
AABR07071287.1 Nucleoside diphosphate
kinase-like domain-containing protein		 Rattus norvegicus
TI:10116 None 		     
E9G4E0_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_237790 Thioredoxin domain-containing protein Daphnia pulex
TI:6669 None 		 
 
M9PHK6_DROME
FlyBase»
0.0
Dmel\CG14221 Uncharacterized protein, isoform C Drosophila melanogaster
TI:7227 None 		 
 
Q9VYR5_DROME
FlyBase»
0.0
Dmel\CG18130 FI06001p Drosophila melanogaster
TI:7227 None 		 
 
T1FXJ1_HELRO
EnsemblMetazoa»
0.0
20213539 Thioredoxin domain-containing protein Helobdella robusta
TI:6412 None 		 
 
W5M771_LEPOC
Ensembl»
0.0
Nucleoside diphosphate
kinase-like domain-containing protein		 Lepisosteus oculatus
TI:7918 None