Collated Gene Ontology terms

Biological process: nucleoside diphosphate kinase activity(2025) microtubule binding(2015, 2022, 2025) 3'-5'-DNA exonuclease activity(2025) hydrolase activity(2025) transferase activity(2025) metal ion binding(2025) kinase activity(2025)

Molecular function: UTP biosynthetic process2025 GTP biosynthetic process2025 CTP biosynthetic process2025 cilium assembly2015, 2022, 2025 DNA catabolic process2025 spermatogenesis2025 flagellated sperm motility2015, 2022 cell differentiation2025 cellular response to reactive oxygen species2015 spermatid development2005
cell redox homeostasis2022

Cellular component: axoneme2020, 2022, 2025 sperm principal piece2015, 2020, 2022, 2025 cytoplasm2020, 2025 nucleus2020, 2025 cytosol2011, 2024, 2025 sperm midpiece2020, 2025 sperm flagellum2025 sperm cytoplasmic droplet2015, 2025 outer dynein arm2015, 2025 dynein axonemal particle2021, 2025
sperm fibrous sheath2015 ruffle2025 nuclear speck2025 mitochondrion2023 lamellipodium2025 cytoskeleton2025 cilium2025

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 1/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8M9Q4G2_DANRE
ZFIN»
0.0
nme9 Thioredoxin domain-containing protein
6 isoform X1		 Danio rerio
TI:7955 None
   
M9PHK6_DROME
FlyBase»
0.0
Dmel\CG14221 Uncharacterized protein, isoform C Drosophila melanogaster
TI:7227 None 		 
 
Q9VYR5_DROME
FlyBase»
0.0
Dmel\CG18130 FI06001p Drosophila melanogaster
TI:7227 None 		 
 
A0A1D5PUV4_CHICK
Ensembl»
0.0
NME8 NME/NM23 family member 8 Gallus gallus
TI:9031 None
   
A0A8V0ZXR7_CHICK
Ensembl»
0.0
Thioredoxin domain-containing protein Gallus gallus
TI:9031 None 		     
NDK8_HUMAN
Ensembl»
4.7
NME8 Protein NME8 (NM23-H8) (NME/NM23 family member 8) (Nucleoside diphosphate kinase 8) (NDK8) (Protein kinase NME8)
(EC 2.7.-.-) (Putative 3'-5'-DNA exonuclease NDK8) (EC 3.1.11.-) (Spermatid-specific thioredoxin-2) (Sptrx-2) (Thioredoxin domain-containing protein 3)		 Homo sapiens
TI:9606 None
 
TXND6_HUMAN
Ensembl»
0.0
NME9 Thioredoxin domain-containing protein 6
(Thioredoxin-like protein 2) (Txl-2)		 Homo sapiens
TI:9606 None
 
NDK8_MOUSE
Ensembl»
6.1
Nme8 Protein NME8 (NME/NM23 family member 8) (Nucleoside diphosphate kinase 8) (NDK8) (Protein kinase NME8)
(EC 2.7.-.-) (Putative 3'-5'-DNA exonuclease NDK8) (EC 3.1.11.-) (Spermatid-specific thioredoxin-2) (Sptrx-2) (Thioredoxin domain-containing protein 3)		 Mus musculus
TI:10090 None
 
TXND6_MOUSE
Ensembl»
0.0
Nme9 Thioredoxin domain-containing protein 6
(Thioredoxin-like protein 2) (Txl-2)		 Mus musculus
TI:10090 None
 
NDK8_RAT
RGD»
6.1
Nme8 Protein NME8 (NME/NM23 family member 8) (Nucleoside diphosphate kinase 8) (NDK8) (Protein kinase NME8)
(EC 2.7.-.-) (Putative 3'-5'-DNA exonuclease NDK8) (EC 3.1.11.-) (Spermatid-specific thioredoxin-2) (Sptrx-2) (Thioredoxin domain-containing protein 3)		 Rattus norvegicus
TI:10116 None