Collated Gene Ontology terms

Biological process: structural molecule activity(2025) molecular adaptor activity(2025) protein homodimerization activity(2022, 2025) cysteine desulfurase activity(2014, 2025) iron-sulfur cluster binding(2011) transferase activity(2025)

Molecular function: iron-sulfur cluster assembly2013, 2025 [2Fe-2S] cluster assembly2018, 2022, 2025 [4Fe-4S] cluster assembly2022 tRNA thio-modification2011

Cellular component: mitochondrion2009, 2011, 2013, 2018, 2022, 2023, 2024, 2025 L-cysteine desulfurase complex2014, 2024, 2025 nucleus2009, 2023, 2025 mitochondrial [2Fe-2S] assembly complex2022, 2024, 2025 nuclear body2025 mitochondrial matrix2005, 2013, 2024, 2025 cytoplasm2017 kinetoplast2025 cytosol2009

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 13/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
LYRM4_HUMAN
Ensembl»
5.3
LYRM4 LYR motif-containing protein 4 Homo sapiens
TI:9606 None
 
ISD11_YEAST
SGD»
4.8
ISD11 Protein ISD11 (Iron-sulfur protein
biogenesis, desulfurase-interacting protein 11)		 Saccharomyces cerevisiae
TI:4932 None
 
LYRM4_MOUSE
Ensembl»
4.4
Lyrm4 LYR motif-containing protein 4 Mus musculus
TI:10090 None
 
LYRM4_DROME
FlyBase»
2.3
bcn92 LYR motif-containing protein
4 homolog (Protein bcn92)		 Drosophila melanogaster
TI:7227 None
 
ISD11_SCHPO
PomBase»
2.0
isd11 Protein isd11 Schizosaccharomyces pombe
TI:4896 None
 
A0A2R8F5A8_CAEEL
WormBase»
1.0
CELE_F53G2.12 F53G2.12 Complex 1 LYR protein domain-containing protein Caenorhabditis elegans
TI:6239 None
 
A0A2R8Q8D7_DANRE
ZFIN»
1.0
LOC103909737 LYR motif-containing
protein 4 (Si:ch211-152c8.4)		 Danio rerio
TI:7955 None
 
A0A8V0YBJ8_CHICK
Ensembl»
1.0
LYRM4 LYR motif containing 4 Gallus gallus
TI:9031 None
   
D3ZYM7_RAT
RGD»
1.0
Lyrm4 LYR motif containing 4 Rattus norvegicus
TI:10116 None
   
LYRM4_DANRE
ZFIN»
1.0
lyrm4 LYR motif-containing protein 4 Danio rerio
TI:7955 None
 
LYRM4_DICDI
dictyBase»
1.0
lyrm4 LYR motif-containing protein 4 Dictyostelium discoideum
TI:44689 None