Standard knownness: 2.6; Custom knownness: None; Num. species: 33; Orthology database: Panther18.0; Protein members: 53
Molecular function: negative regulation of actin filament depolymerization2013, 2021, 2023 neuron differentiation2023 animal organ morphogenesis2023 system development2023 motor neuron axon guidance2017, 2022 signal transduction2023 branching involved in blood vessel morphogenesis2006 blood vessel morphogenesis2006 axon guidance2006 G protein-coupled receptor signaling pathway2023
Cellular component:
cytoskeleton2023
cytoplasm2010, 2013, 2021, 2023
plasma membrane2013, 2023
lamellipodium2013, 2023
cortical actin cytoskeleton2013, 2023
nucleoplasm2023
nuclear body2023
cytosol2023
membrane2023
cell periphery2023
cell projection2023
Chordates: | 20/21 | |
Echinoderms: | 0/0 | |
Hemichordates: | 1/1 | |
Annelids: | 1/1 | |
Molluscs: | 0/0 | |
Bryozoans: | 0/0 | |
Platyhelminthes: | 0/0 | |
Rotifers: | 0/0 | |
Nematodes: | 3/3 | |
Arthropods: | 5/5 | |
Tardigrades: | 0/0 | |
Placozoa: | 1/1 | |
Cnidaria: | 1/1 | |
Porifera: | 0/0 | |
Choanoflagellates+: | 1/1 | |
Dikarya: | 0/14 | |
Fungi (other): | 0/1 | |
Protozoa: | 0/3 | |
Excavates: | 0/4 | |
Harosa: | 0/4 | |
Hacrobia: | 0/0 | |
Plants: | 0/39 | |
Archea: | 0/8 | |
Bacteria: | 0/35 |
UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
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Y34F_DROME FlyBase» |
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CG43867 | Uncharacterized protein CG43867 |
Drosophila melanogaster TI:7227 None |
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B7P3I2_IXOSC EnsemblMetazoa» |
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IscW_ISCW000929 | PlekhH1, putative (EC 2.4.1.173) (PlekhH1, putative (Fragment)) |
Ixodes scapularis TI:6945 None |
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G3RA52_GORGO Ensembl» |
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Pleckstrin homology, MyTH4 and FERM domain containing H2 |
Gorilla gorilla TI:9593 None |
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PKHH2_MOUSE Ensembl» |
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Plekhh2 | Pleckstrin homology domain-containing family H member 2 |
Mus musculus TI:10090 None |
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PKHH1_MOUSE Ensembl» |
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Plekhh1 | Pleckstrin homology domain-containing family H member 1 (PH domain-containing family H member 1) |
Mus musculus TI:10090 None |
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PKHH1_HUMAN Ensembl» |
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PLEKHH1 | Pleckstrin homology domain-containing family H member 1 (PH domain-containing family H member 1) |
Homo sapiens TI:9606 None |
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PKHH2_HUMAN Ensembl» |
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PLEKHH2 | Pleckstrin homology domain-containing family H member 2 |
Homo sapiens TI:9606 None |
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I3LFD9_PIG Ensembl» |
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PLEKHH2 | Pleckstrin homology domain-containing family H member 2 (Pleckstrin homology, MyTH4 and FERM domain containing H2) |
Sus scrofa TI:9823 None |
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G5ED24_CAEEL WormBase» |
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max-1 | MAX-1A (PH domain-containing protein) |
Caenorhabditis elegans TI:6239 None |
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T1ENW0_HELRO EnsemblMetazoa» |
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20198260 | FERM domain-containing protein |
Helobdella robusta TI:6412 None |
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A0A139WJC1_TRICA EnsemblMetazoa» |
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AUGUSTUS-3.0.2_08185 | Uncharacterized protein CG43867-like Protein |
Tribolium castaneum TI:7070 None |
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A0A1S4GDI2_ANOGA EnsemblMetazoa» |
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Plekhh1 |
Anopheles gambiae TI:7165 None |
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A0A2A6CS72_PRIPA EnsemblMetazoa» |
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WBGene00203219 | Max-1 |
Pristionchus pacificus TI:54126 None |
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A0A2I2YBJ3_GORGO Ensembl» |
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PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Gorilla gorilla TI:9593 None |
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A7RZW1_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g99085 | Uncharacterized protein |
Nematostella vectensis TI:45351 None |
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A7T3D1_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g221761 | MyTH4 domain-containing protein |
Nematostella vectensis TI:45351 None |
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A7T3D2_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g221763 | Uncharacterized protein |
Nematostella vectensis TI:45351 None |
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A8X936_CAEBR WormBase» |
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max-1.2 | Protein CBR-MAX-1 |
Caenorhabditis briggsae TI:6238 None |
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A8X938_CAEBR WormBase» |
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max-1.1 | Protein CBG09439 |
Caenorhabditis briggsae TI:6238 None |
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A9VBE1_MONBE EnsemblProtists» |
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MONBRDRAFT_34394 | PH domain-containing protein |
Monosiga brevicollis TI:81824 None |
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B3SDC8_TRIAD EnsemblMetazoa» |
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TRIADDRAFT_33842 | MyTH4 domain-containing protein |
Trichoplax adhaerens TI:10228 None |
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E9G354_DAPPU EnsemblMetazoa» |
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DAPPUDRAFT_308469 | PH domain-containing protein |
Daphnia pulex TI:6669 None |
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H2QHT8_PANTR Ensembl» |
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PLEKHH2 | Pleckstrin homology, MyTH4 and FERM domain containing H2 |
Pan troglodytes TI:9598 None |
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H2R9A1_PANTR Ensembl» |
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PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Pan troglodytes TI:9598 None |
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H2Y1W2_CIOIN Ensembl» |
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Uncharacterized protein |
Ciona intestinalis TI:7719 None |
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M3WIW4_FELCA Ensembl» |
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PLEKHH2 | Pleckstrin homology, MyTH4 and FERM domain containing H2 |
Felis catus TI:9685 None |
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M3WK16_FELCA Ensembl» |
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PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Felis catus TI:9685 None |
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PKHH1_DANRE ZFIN» |
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plekhh1 | Pleckstrin homology domain-containing family H member 1 (PH domain-containing family H member 1) (Protein max-1 homolog) |
Danio rerio TI:7955 None |
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W5N9C0_LEPOC Ensembl» |
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Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Lepisosteus oculatus TI:7918 None |
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W5NI31_LEPOC Ensembl» |
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Pleckstrin homology, MyTH4 and FERM domain containing H2 |
Lepisosteus oculatus TI:7918 None |
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A0A5F5PYH8_HORSE Ensembl» |
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PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Equus caballus TI:9796 None |
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A0A7M7T5N6_STRPU EnsemblMetazoa» |
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Pleckstrin homology domain-containing family H member 2 |
Strongylocentrotus purpuratus TI:7668 None |
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A0A8I3MK66_CANLF Ensembl» |
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PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Canis lupus TI:9612 None |
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A0A8I3PKY1_CANLF Ensembl» |
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PLEKHH2 | Pleckstrin homology, MyTH4 and FERM domain containing H2 |
Canis lupus TI:9612 None |
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A0A8M9QFR0_DANRE CTD» |
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plekhh2 | Pleckstrin homology domain-containing family H member 2 |
Danio rerio TI:7955 None |
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A0A8V0ZCE8_CHICK Ensembl» |
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PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Gallus gallus TI:9031 None |
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A0A8V0ZK98_CHICK Ensembl» |
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PLEKHH2 | Pleckstrin homology, MyTH4 and FERM domain containing H2 |
Gallus gallus TI:9031 None |
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A0A9J7LCN9_BRAFL CTD» |
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LOC118418046 | Pleckstrin homology domain-containing family H member 1-like isoform X1 |
Branchiostoma floridae TI:7739 None |
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D3ZNS6_RAT RGD» |
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Plekhh2 | Pleckstrin homology, MyTH4 and FERM domain containing H2 |
Rattus norvegicus TI:10116 None |
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D4AA54_RAT RGD» |
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Plekhh1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Rattus norvegicus TI:10116 None |
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E1BF01_BOVIN Ensembl» |
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PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Bos taurus TI:9913 None |
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F1MH50_BOVIN Ensembl» |
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PLEKHH2 | Pleckstrin homology, MyTH4 and FERM domain containing H2 |
Bos taurus TI:9913 None |
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F1SA37_PIG Ensembl» |
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PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Sus scrofa TI:9823 None |
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F6SWM6_HORSE Ensembl» |
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PLEKHH2 | Pleckstrin homology, MyTH4 and FERM domain containing H2 |
Equus caballus TI:9796 None |
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F6URG8_MACMU Ensembl» |
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PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Macaca mulatta TI:9544 None |
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F6Y5I6_MONDO Ensembl» |
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PLEKHH2 | Pleckstrin homology, MyTH4 and FERM domain containing H2 |
Monodelphis domestica TI:13616 None |
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F6ZRY3_MACMU Ensembl» |
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PLEKHH2 | Pleckstrin homology, MyTH4 and FERM domain containing H2 |
Macaca mulatta TI:9544 None |
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F7CHP0_XENTR Xenbase» |
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plekhh2 | Pleckstrin homology domain-containing family H member 2 (Pleckstrin homology, MyTH4 and FERM domain-containing H2) |
Xenopus tropicalis TI:8364 None |
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F7FLH1_MONDO Ensembl» |
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PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Monodelphis domestica TI:13616 None |
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H2L7N6_ORYLA Ensembl» |
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plekhh2 | Pleckstrin homology, MyTH4 and FERM domain containing H2 |
Oryzias latipes TI:8090 None |
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H2LXB5_ORYLA Ensembl» |
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plekhh1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Oryzias latipes TI:8090 None |
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H9GAG7_ANOCA Ensembl» |
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PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 |
Anolis carolinensis TI:28377 None |
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H9GLZ3_ANOCA Ensembl» |
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PLEKHH2 | Pleckstrin homology, MyTH4 and FERM domain containing H2 |
Anolis carolinensis TI:28377 None |
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