Collated Gene Ontology terms

Biological process: actin binding(2013, 2021, 2024) sterol 3-beta-glucosyltransferase activity(2024) glycosyltransferase activity(2024) G protein-coupled receptor activity(2024) G protein-coupled peptide receptor activity(2024)

Molecular function: negative regulation of actin filament depolymerization2013, 2021, 2024 animal organ morphogenesis2024 neuron differentiation2024 system development2024 motor neuron axon guidance2017 branching involved in blood vessel morphogenesis2006 blood vessel morphogenesis2006 axon guidance2006 G protein-coupled receptor signaling pathway2024

Cellular component: cytoskeleton2024 cytoplasm2013, 2021, 2024 plasma membrane2013, 2023, 2024 lamellipodium2013, 2024 cortical actin cytoskeleton2013, 2024 nucleoplasm2023, 2024 nuclear body2023, 2024 cytosol2023, 2024 cell periphery2024 membrane2024
cell projection2024

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
H9GAG7_ANOCA
Ensembl»
0.0
PLEKHH1 Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Anolis carolinensis
TI:28377 None
   
H9GLZ3_ANOCA
Ensembl»
0.0
PLEKHH2 Pleckstrin homology, MyTH4 and
FERM domain containing H2		 Anolis carolinensis
TI:28377 None
   
A0A1S4GDI2_ANOGA
EnsemblMetazoa»
0.0
Plekhh1 Anopheles gambiae
TI:7165 None
 
E1BF01_BOVIN
Ensembl»
0.0
PLEKHH1 Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Bos taurus
TI:9913 None
   
F1MH50_BOVIN
Ensembl»
0.0
PLEKHH2 Pleckstrin homology, MyTH4 and
FERM domain containing H2		 Bos taurus
TI:9913 None
   
A0A9J7LCN9_BRAFL
CTD»
0.0
LOC118418046 Pleckstrin homology domain-containing family
H member 1-like isoform X1		 Branchiostoma floridae
TI:7739 None
   
A8X936_CAEBR
WormBase»
0.0
max-1.2 Protein CBR-MAX-1 Caenorhabditis briggsae
TI:6238 None
 
A8X938_CAEBR
WormBase»
0.0
max-1.1 Protein CBG09439 Caenorhabditis briggsae
TI:6238 None
 
G5ED24_CAEEL
WormBase»
0.8
max-1 MAX-1A (PH domain-containing protein) Caenorhabditis elegans
TI:6239 None
 
A0A8I3MK66_CANLF
Ensembl»
0.0
PLEKHH1 Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Canis lupus
TI:9612 None
   
A0A8I3PKY1_CANLF
Ensembl»
0.0
PLEKHH2 Pleckstrin homology, MyTH4 and
FERM domain containing H2		 Canis lupus
TI:9612 None
   
H2Y1W2_CIOIN
Ensembl»
0.0
Uncharacterized protein Ciona intestinalis
TI:7719 None
 
A0A8M9QFR0_DANRE
CTD»
1.0
plekhh2 Pleckstrin homology domain-containing
family H member 2		 Danio rerio
TI:7955 None
   
PKHH1_DANRE
ZFIN»
2.4
plekhh1 Pleckstrin homology domain-containing family H member 1 (PH
domain-containing family H member 1) (Protein max-1 homolog)		 Danio rerio
TI:7955 None
 
E9G354_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_308469 PH domain-containing protein Daphnia pulex
TI:6669 None
 
Y34F_DROME
FlyBase»
0.0
CG43867 Uncharacterized protein CG43867 Drosophila melanogaster
TI:7227 None
 
F6SWM6_HORSE
Ensembl»
0.0
PLEKHH2 Pleckstrin homology, MyTH4 and
FERM domain containing H2		 Equus caballus
TI:9796 None
   
F6VU91_HORSE
Ensembl»
0.0
PLEKHH1 Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Equus caballus
TI:9796 None
   
M3WIW4_FELCA
Ensembl»
0.0
PLEKHH2 Pleckstrin homology, MyTH4 and
FERM domain containing H2		 Felis catus
TI:9685 None
 
M3WK16_FELCA
Ensembl»
0.0
PLEKHH1 Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Felis catus
TI:9685 None
 
A0A8V0ZCE8_CHICK
Ensembl»
0.0
PLEKHH1 Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Gallus gallus
TI:9031 None
   
A0A8V0ZK98_CHICK
Ensembl»
0.0
PLEKHH2 Pleckstrin homology, MyTH4 and
FERM domain containing H2		 Gallus gallus
TI:9031 None
   
A0A2I2YBJ3_GORGO
Ensembl»
0.0
PLEKHH1 Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Gorilla gorilla
TI:9593 None
 
G3RA52_GORGO
Ensembl»
0.0
Pleckstrin homology, MyTH4 and
FERM domain containing H2		 Gorilla gorilla
TI:9593 None
 
T1ENW0_HELRO
EnsemblMetazoa»
0.0
20198260 FERM domain-containing protein Helobdella robusta
TI:6412 None
 
PKHH1_HUMAN
Ensembl»
0.0
PLEKHH1 Pleckstrin homology domain-containing family H member
1 (PH domain-containing family H member 1)		 Homo sapiens
TI:9606 None
 
PKHH2_HUMAN
Ensembl»
2.0
PLEKHH2 Pleckstrin homology domain-containing
family H member 2		 Homo sapiens
TI:9606 None
 
B7P3I2_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW000929 PlekhH1, putative (EC
2.4.1.173) (PlekhH1, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
W5N9C0_LEPOC
Ensembl»
0.0
Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Lepisosteus oculatus
TI:7918 None
 
W5NI31_LEPOC
Ensembl»
0.0
Pleckstrin homology, MyTH4 and
FERM domain containing H2		 Lepisosteus oculatus
TI:7918 None
 
F6URG8_MACMU
Ensembl»
0.0
PLEKHH1 Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Macaca mulatta
TI:9544 None
   
F6ZRY3_MACMU
Ensembl»
0.0
PLEKHH2 Pleckstrin homology, MyTH4 and
FERM domain containing H2		 Macaca mulatta
TI:9544 None
   
F6Y5I6_MONDO
Ensembl»
0.0
PLEKHH2 Pleckstrin homology, MyTH4 and
FERM domain containing H2		 Monodelphis domestica
TI:13616 None
   
F7FLH1_MONDO
Ensembl»
0.0
PLEKHH1 Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Monodelphis domestica
TI:13616 None
   
A9VBE1_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_34394 PH domain-containing protein Monosiga brevicollis
TI:81824 None
 
PKHH1_MOUSE
Ensembl»
0.0
Plekhh1 Pleckstrin homology domain-containing family H member
1 (PH domain-containing family H member 1)		 Mus musculus
TI:10090 None
 
PKHH2_MOUSE
Ensembl»
1.6
Plekhh2 Pleckstrin homology domain-containing
family H member 2		 Mus musculus
TI:10090 None
 
A7RZW1_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g99085 Uncharacterized protein Nematostella vectensis
TI:45351 None
 
A7T3D1_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g221761 MyTH4 domain-containing protein Nematostella vectensis
TI:45351 None
 
A7T3D2_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g221763 Uncharacterized protein Nematostella vectensis
TI:45351 None 		 
 
H2L7N6_ORYLA
Ensembl»
0.0
plekhh2 Pleckstrin homology, MyTH4 and
FERM domain containing H2		 Oryzias latipes
TI:8090 None
   
H2LXB5_ORYLA
Ensembl»
0.0
plekhh1 Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Oryzias latipes
TI:8090 None
   
H2QHT8_PANTR
Ensembl»
0.0
PLEKHH2 Pleckstrin homology, MyTH4 and
FERM domain containing H2		 Pan troglodytes
TI:9598 None
 
H2R9A1_PANTR
Ensembl»
0.0
PLEKHH1 Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Pan troglodytes
TI:9598 None
 
A0A2A6CS72_PRIPA
EnsemblMetazoa»
0.0
WBGene00203219 Max-1 Pristionchus pacificus
TI:54126 None
 
D3ZNS6_RAT
RGD»
2.0
Plekhh2 Pleckstrin homology, MyTH4 and
FERM domain containing H2		 Rattus norvegicus
TI:10116 None
   
D4AA54_RAT
RGD»
0.0
Plekhh1 Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Rattus norvegicus
TI:10116 None
   
A0A7M7T5N6_STRPU
EnsemblMetazoa»
0.0
Pleckstrin homology domain-containing
family H member 2		 Strongylocentrotus purpuratus
TI:7668 None
   
F1SA37_PIG
Ensembl»
0.0
PLEKHH1 Pleckstrin homology, MyTH4 and
FERM domain containing H1		 Sus scrofa
TI:9823 None
   
I3LFD9_PIG
Ensembl»
0.0
PLEKHH2 Pleckstrin homology domain-containing family H member 2
(Pleckstrin homology, MyTH4 and FERM domain containing H2)		 Sus scrofa
TI:9823 None
 
A0A139WJC1_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_08185 Uncharacterized protein CG43867-like Protein Tribolium castaneum
TI:7070 None
 
B3SDC8_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_33842 MyTH4 domain-containing protein Trichoplax adhaerens
TI:10228 None
 
A0A1L8G199_XENLA
Xenbase»
0.0
plekhh2.S Pleckstrin homology domain-containing family
H member 2 isoform X1		 Xenopus laevis
TI:8355 None
   
A0A8J1KM77_XENLA
Xenbase»
0.0
LOC121393598 Pleckstrin homology domain-containing
family H member 2-like		 Xenopus laevis
TI:8355 None
   
A0A8J1KM90_XENLA
Xenbase»
0.0
plekhh2.L Pleckstrin homology domain-containing
family H member 2		 Xenopus laevis
TI:8355 None
   
F7CHP0_XENTR
Xenbase»
0.0
plekhh2 Pleckstrin homology domain-containing family H member 2
(Pleckstrin homology, MyTH4 and FERM domain-containing H2)		 Xenopus tropicalis
TI:8364 None