Collated Gene Ontology terms

Biological process: metal ion binding(2024) lyase activity(2024) 6-pyruvoyltetrahydropterin synthase activity(2003, 2005, 2007, 2008, 2016, 2024) 6-carboxy-5,6,7,8-tetrahydropterin synthase activity(2009, 2017, 2024) identical protein binding(2014, 2019, 2024) zinc ion binding(2011)

Molecular function: tetrahydrobiopterin biosynthetic process2003, 2005, 2007, 2008, 2016, 2024 queuosine biosynthetic process2017, 2024 response to oxidative stress2015, 2024 folic acid biosynthetic process2005, 2024 response to Gram-negative bacterium2020 pteridine biosynthetic process2006 central nervous system development2003 amino acid metabolic process2003

Cellular component: mitochondrion2009, 2010, 2017, 2024 cytoplasm2010, 2024 membrane2024 cytosol2013

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 6/8 
Bacteria: 27/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
PTPS_HUMAN
Ensembl»
4.4
PTS 6-pyruvoyl tetrahydrobiopterin synthase (PTP
synthase) (PTPS) (EC 4.2.3.12)		 Homo sapiens
TI:9606 None
 
PTPS_MOUSE
Ensembl»
2.4
Pts 6-pyruvoyl tetrahydrobiopterin synthase (PTP
synthase) (PTPS) (EC 4.2.3.12)		 Mus musculus
TI:10090 None
 
PTPS_DROME
FlyBase»
1.6
pr 6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS)
(EC 4.2.3.12) (Protein purple) (Sepiapterin synthase A)		 Drosophila melanogaster
TI:7227 None
 
QUED_ECOLI
EnsemblBacteria»
3.7
queD 6-carboxy-5,6,7,8-tetrahydropterin synthase (CPH4 synthase) (EC
4.1.2.50) (Queuosine biosynthesis protein QueD)		 Escherichia coli
TI:562 None
 
PTPS_CAEEL
WormBase»
2.4
ptps-1 Putative 6-pyruvoyl tetrahydrobiopterin synthase
(PTP synthase) (PTPS) (EC 4.2.3.12)		 Caenorhabditis elegans
TI:6239 None
 
PTPS_RAT
RGD»
3.2
Pts 6-pyruvoyl tetrahydrobiopterin synthase (PTP
synthase) (PTPS) (EC 4.2.3.12)		 Rattus norvegicus
TI:10116 None
 
A5PKS5_DANRE
ZFIN»
0.0
ptps 6-pyruvoyl tetrahydrobiopterin synthase (PTP
synthase) (PTPS) (EC 4.2.3.12)		 Danio rerio
TI:7955 None
 
PTPS_DICDI
dictyBase»
2.9
ptsA 6-pyruvoyl tetrahydrobiopterin synthase (PTP
synthase) (PTPS) (EC 4.2.3.12)		 Dictyostelium discoideum
TI:44689 None
 
A0A8V1A5P5_CHICK
Ensembl»
0.0
PTS 6-pyruvoyl tetrahydrobiopterin
synthase (EC 4.2.3.12)		 Gallus gallus
TI:9031 None