Collated Gene Ontology terms

Biological process: dioxygenase activity(2025) oxidoreductase activity(2025) metal ion binding(2025) tRNA demethylase activity(2025) oxidative RNA demethylase activity(2025) 2-oxoglutarate-dependent dioxygenase activity(2022, 2025) transferase activity(2025) tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity(2023, 2025) methyltransferase activity(2025) histone binding(2011, 2025)
ferrous iron binding2011, 2025 tRNA binding2017 protein kinase activity2025 nucleotide binding2025 L-ascorbic acid binding2025 ATP binding2025

Molecular function: DNA damage response2013, 2025 fatty acid metabolic process2013, 2014, 2021, 2025 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death2014, 2024, 2025 programmed cell death2025 oxidative RNA demethylation2025 regulation of lipid storage2013, 2025 methylation2025 cellular response to hypoxia2009, 2025 tRNA wobble uridine modification2024 tRNA methylation2025

Cellular component: mitochondrial matrix2013, 2021, 2024, 2025 mitochondrion2009, 2014, 2024, 2025 nucleus2009, 2011, 2018, 2025 cytoplasm2017, 2025 nuclear lumen2017 ciliary plasm2017 chromatin2015, 2025 nucleolus2011 kinetoplast2025 cytosol2009

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 6/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 2/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q1ECQ5_ARATH
TAIR»
0.5
At4g02485 2-oxoglutarate (2OG) and Fe(II)-dependent
oxygenase superfamily protein (At4g02485)		 Arabidopsis thaliana
TI:3702 None
 
Q7YWP5_CAEEL
WormBase»
0.5
alkb-7 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
Q566X4_DANRE
ZFIN»
0.5
alkbh7 Alpha-ketoglutarate-dependent dioxygenase alkB
homolog 7, mitochondrial (Zgc:112404)		 Danio rerio
TI:7955 None
 
M0R7T2_RAT
RGD»
4.0
Alkbh7 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial
(Alkylated DNA repair protein alkB homolog 7)		 Rattus norvegicus
TI:10116 None
   
Q9VTP1_DROME
FlyBase»
1.5
Dmel\CG14130 IP06473p Drosophila melanogaster
TI:7227 None
 
ALKB7_MOUSE
Ensembl»
7.1
Alkbh7 RNA demethylase ALKBH7, mitochondrial (EC 1.14.11.-) (Alkylated DNA repair
protein alkB homolog 7) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial)		 Mus musculus
TI:10090 None
 
ALKB7_HUMAN
Ensembl»
5.5
ALKBH7 RNA demethylase ALKBH7, mitochondrial (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 7) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7,
mitochondrial) (Spermatogenesis cell proliferation-related protein) (Spermatogenesis-associated protein 11) (pre-tRNA N1-methyl adenine demethylase ALKBH7) (pre-tRNA N2-dimethyl guanosine demethylase ALKBH7)		 Homo sapiens
TI:9606 None
 
YLW2_SCHPO
PomBase»
4.2
SPAP8A3.02c Uncharacterized protein P8A3.02c Schizosaccharomyces pombe
TI:4896 None