Collated Gene Ontology terms

Biological process: dioxygenase activity(2024) 2-oxoglutarate-dependent dioxygenase activity(2006, 2022, 2024) metal ion binding(2024) tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity(2023, 2024) methyltransferase activity(2024) histone binding(2011, 2024) ferrous iron binding(2011, 2024) tRNA binding(2017) protein kinase activity(2024) oxidoreductase activity(2024)
L-ascorbic acid binding2024 ATP binding2024

Molecular function: DNA damage response2013, 2024 fatty acid metabolic process2013, 2014, 2021, 2024 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death2014, 2024 regulation of lipid storage2013, 2024 programmed cell death2024 methylation2024 cellular response to hypoxia2009, 2024 tRNA wobble uridine modification2021 tRNA methylation2022 protein phosphorylation2024

Cellular component: mitochondrial matrix2013, 2021, 2024 mitochondrion2009, 2014, 2023, 2024 nucleus2009, 2011, 2023, 2024 cytoplasm2017, 2022, 2024 nuclear lumen2017 ciliary plasm2017 chromatin2015, 2024 nucleolus2011 membrane2024 cytosol2009

Phylogenetic distribution

Chordates: 19/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 6/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 2/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A022S360_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a012176mg Fe2OG dioxygenase domain-containing protein Erythranthe guttata
TI:4155 None
 
A0A061DRI2_THECC
EnsemblPlants»
0.0
TCM_004624 2-oxoglutarate and Fe(II)-dependent
oxygenase superfamily protein		 Theobroma cacao
TI:3641 None
 
A0A067HGW5_CITSI
Ensembl»
0.0
CISIN_1g024968mg Fe2OG dioxygenase domain-containing protein Citrus sinensis
TI:2711 None
 
A0A078G9N5_BRANA
EnsemblPlants»
0.0
BnaA09g00830D (rape) hypothetical
protein (BnaA09g00830D protein)		 Brassica napus
TI:3708 None
 
A0A078IHE7_BRANA
EnsemblPlants»
0.0
BnaCnng19120D BnaCnng19120D protein Brassica napus
TI:3708 None
 
A0A0A0KV56_CUCSA
EnsemblPlants»
0.0
Csa_4G001660 Fe2OG dioxygenase domain-containing protein Cucumis sativus
TI:3659 None
 
A0A0Q3L4A4_BRADI
EnsemblPlants»
0.0
100835151 Fe2OG dioxygenase domain-containing protein Brachypodium distachyon
TI:15368 None
 
A0A0R0GIH9_SOYBN
EnsemblPlants»
0.0
GLYMA_14G026500 Protein kinase domain-containing protein Glycine max
TI:3847 None
 
A0A139WDN1_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_33955 Alpha-ketoglutarate-dependent dioxygenase alkB
homolog 7, mitochondrial-like Protein		 Tribolium castaneum
TI:7070 None
 
A0A1D5RAC5_MACMU
Ensembl»
0.0
ALKBH7 AlkB homolog 7 Macaca mulatta
TI:9544 None
   
A0A1L8H331_XENLA
Xenbase»
0.0
alkbh7.L Alpha-ketoglutarate-dependent dioxygenase alkB homolog
7, mitochondrial isoform X1		 Xenopus laevis
TI:8355 None
   
A0A1S3Z8F0_TOBAC
EnsemblFungi»
0.0
LOC107784116 Alkylated DNA repair protein
alkB homolog 8-like isoform X1		 Nicotiana tabacum
TI:4097 None
   
A0A1S4B1G8_TOBAC
EnsemblFungi»
0.0
LOC107803554 Alkylated DNA repair protein
alkB homolog 8-like isoform X1		 Nicotiana tabacum
TI:4097 None
   
A0A1U8ABW5_NELNU
EnsemblBacteria»
0.0
LOC104598977 Alkylated DNA repair protein
alkB homolog 8 isoform X5		 Nelumbo nucifera
TI:4432 None
   
A0A1U8LQR0_GOSHI
Ensembl»
0.0
LOC107929857 Alkylated DNA repair protein alkB homolog 8-like Gossypium hirsutum
TI:3635 None
   
A0A1U8MSY5_GOSHI
Ensembl»
0.0
LOC107940991 Alkylated DNA repair protein alkB homolog 8-like Gossypium hirsutum
TI:3635 None
   
A0A1Y1I2R0_KLENI
EnsemblPlants»
0.0
KFL_002240070 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Klebsormidium nitens
TI:105231 None
 
A0A251S4R7_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr15g0465711 HanXRQr2_Chr15g0673401 Putative 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase
superfamily protein (tRNA (Carboxymethyluridine(34)-5-O)-methyltransferase (EC 2.1.1.229))		 Helianthus annuus
TI:4232 None
 
A0A2C9VTV7_MANES
EnsemblPlants»
0.0
MANES_05G063800 Fe2OG dioxygenase domain-containing protein Manihot esculenta
TI:3983 None
 
A0A2G2ZW56_CAPAN
EnsemblPlants»
0.0
T459_08301 Fe2OG dioxygenase domain-containing protein Capsicum annuum
TI:4072 None
 
A0A2I2YF29_GORGO
Ensembl»
0.0
ALKBH7 AlkB homolog 7 Gorilla gorilla
TI:9593 None
 
A0A2I4E758_JUGRE
EnsemblPlants»
0.0
LOC108986878 Alkylated DNA repair protein ALKBH8 homolog Juglans regia
TI:51240 None
 
A0A2K1IYQ8_PHYPA
EnsemblPlants»
0.0
PHYPA_024224 Fe2OG dioxygenase domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A2K1XUW5_POPTR
EnsemblPlants»
0.0
POPTR_014G131200 Fe2OG dioxygenase domain-containing protein Populus trichocarpa
TI:3694 None
 
A0A2K3CS77_CHLRE
EnsemblPlants»
0.0
CHLRE_16g695851v5 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6XSS9_MARPO
EnsemblPlants»
0.0
MARPO_0003s0075 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Marchantia polymorpha
TI:3197 None
 
A0A3B6NVV8_WHEAT
EnsemblPlants»
0.0
CFC21_084749 Fe2OG dioxygenase domain-containing protein Triticum aestivum
TI:4565 None
 
A0A3B6PT00_WHEAT
EnsemblPlants»
0.0
CFC21_089520 Fe2OG dioxygenase domain-containing protein Triticum aestivum
TI:4565 None
 
A0A3B6QM43_WHEAT
EnsemblPlants»
0.0
CFC21_093969 Fe2OG dioxygenase domain-containing protein Triticum aestivum
TI:4565 None
 
A0A3Q7I5Q5_SOLLC
EnsemblPlants»
0.0
101250926 Fe2OG dioxygenase domain-containing protein Solanum lycopersicum
TI:4081 None
   
A0A6I8PNL5_ORNAN
Ensembl»
0.0
ALKBH7 AlkB homolog 7 Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7HKI6_STRPU
EnsemblMetazoa»
0.0
Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A803SXG8_ANOCA
Ensembl»
0.0
alkbh7 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Anolis carolinensis
TI:28377 None
   
A0A804L8N8_MUSAM
EnsemblPlants»
0.0
Fe2OG dioxygenase domain-containing protein Musa acuminata
TI:4641 None
   
A0A804MVY1_MAIZE
EnsemblPlants»
0.0
Fe2OG dioxygenase domain-containing protein Zea mays
TI:4577 None
   
A0A8I3NI00_CANLF
Ensembl»
0.0
ALKBH7 AlkB homolog 7 Canis lupus
TI:9612 None
   
A0A9J7NCK1_BRAFL
CTD»
0.0
LOC118431761 Alpha-ketoglutarate-dependent dioxygenase alkB
homolog 7, mitochondrial-like		 Branchiostoma floridae
TI:7739 None
   
A7SDG8_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g114209 Uncharacterized protein Nematostella vectensis
TI:45351 None
 
A8X5C5_CAEBR
WormBase»
0.0
alkb-7 Protein CBG07885 Caenorhabditis briggsae
TI:6238 None
 
A9UXP3_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_24773 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Monosiga brevicollis
TI:81824 None
 
A9UXP9_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_24779 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Monosiga brevicollis
TI:81824 None
 
ALKB7_BOVIN
Ensembl»
0.0
ALKBH7 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial (EC
1.14.11.-) (Alkylated DNA repair protein alkB homolog 7)		 Bos taurus
TI:9913 None
 
ALKB7_HUMAN
Ensembl»
3.1
ALKBH7 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial (EC 1.14.11.-) (Alkylated DNA repair
protein alkB homolog 7) (Spermatogenesis cell proliferation-related protein) (Spermatogenesis-associated protein 11)		 Homo sapiens
TI:9606 None
 
ALKB7_MOUSE
Ensembl»
3.4
Alkbh7 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial (EC
1.14.11.-) (Alkylated DNA repair protein alkB homolog 7)		 Mus musculus
TI:10090 None
 
B3S3R8_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_28544 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Trichoplax adhaerens
TI:10228 None
 
B6JV21_SCHJY
EnsemblFungi»
0.0
SJAG_00221 2 OG-Fe(II) oxygenase superfamily protein Ofd2 Schizosaccharomyces japonicus
TI:4897 None
 
B7PDP2_IXOSC
EnsemblMetazoa»
0.0
8028371 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Ixodes scapularis
TI:6945 None
 
B8BQR0_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_31380 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Thalassiosira pseudonana
TI:35128 None
 
B9T0W3_RICCO
EnsemblBacteria»
0.0
RCOM_1439870 Fe2OG dioxygenase domain-containing protein Ricinus communis
TI:3988 None
 
C5Y7E7_SORBI
EnsemblPlants»
0.0
SORBI_3005G204400 Fe2OG dioxygenase domain-containing protein Sorghum bicolor
TI:4558 None
 
D7U265_VITVI
EnsemblPlants»
0.0
VIT_07s0005g00160 Fe2OG dioxygenase domain-containing protein Vitis vinifera
TI:29760 None
 
D8QT65_SELML
EnsemblPlants»
0.0
SELMODRAFT_165238 Fe2OG dioxygenase domain-containing protein Selaginella moellendorffii
TI:88036 None
 
D8R2E8_SELML
EnsemblPlants»
0.0
SELMODRAFT_230539 Fe2OG dioxygenase domain-containing protein Selaginella moellendorffii
TI:88036 None
 
E3JUY1_PUCGT
EnsemblFungi»
0.0
PGTG_01187 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Puccinia graminis
TI:5297 None
 
E3L532_PUCGT
EnsemblFungi»
0.0
PGTG_17513 Fe2OG dioxygenase domain-containing protein Puccinia graminis
TI:5297 None
 
E9GBB5_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_100794 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Daphnia pulex
TI:6669 None
 
F1SBT3_PIG
Ensembl»
0.0
ALKBH7 AlkB homolog 7 Sus scrofa
TI:9823 None
   
F4NSQ8_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_22164 Fe2OG dioxygenase domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F4NXK5_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_22790 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Batrachochytrium dendrobatidis
TI:109871 None
 
F4P2L5_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_88958 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Batrachochytrium dendrobatidis
TI:109871 None
 
F4PF23_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_15023 Fe2OG dioxygenase domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F4PF30_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_15031 Fe2OG dioxygenase domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F5HJY0_ANOGA
EnsemblMetazoa»
0.0
1272350 AGAP000760-PA (AGAP000760-PB) (AGAP000760-PC) Anopheles gambiae
TI:7165 None
 
F6WL76_XENTR
Xenbase»
0.0
alkbh7 AlkB homolog 7 (Alpha-ketoglutarate-dependent
dioxygenase alkB homolog 7, mitochondrial)		 Xenopus tropicalis
TI:8364 None
   
F7AW28_CIOIN
Ensembl»
0.0
Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Ciona intestinalis
TI:7719 None
 
G7K3F0_MEDTR
EnsemblPlants»
0.0
11436623 2OG-Fe(II) oxygenase family oxidoreductase
(Putative tRNA (Carboxymethyluridine(34)-5-O)-methyltransferase (EC 2.1.1.229))		 Medicago truncatula
TI:3880 None
 
H2MX03_ORYLA
Ensembl»
0.0
alkbh7 AlkB homolog 7 Oryzias latipes
TI:8090 None
   
H2QF45_PANTR
Ensembl»
0.0
ALKBH7 AlkB homolog 7 (AlkB,
alkylation repair homolog 7)		 Pan troglodytes
TI:9598 None
 
H3H396_PHYRM
EnsemblProtists»
0.0
Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Phytophthora ramorum
TI:164328 None
 
K3ZMH9_SETIT
EnsemblPlants»
0.0
101759691 Fe2OG dioxygenase domain-containing protein Setaria italica
TI:4555 None
 
M0R7T2_RAT
RGD»
3.0
Alkbh7 AlkB homolog 7 Rattus norvegicus
TI:10116 None
   
M0VAG3_HORVV
EnsemblPlants»
0.0
Uncharacterized protein Hordeum vulgare
TI:4513 None
   
M1AT59_SOLTU
EnsemblPlants»
0.0
Fe2OG dioxygenase domain-containing protein Solanum tuberosum
TI:4113 None
   
M3WH32_FELCA
Ensembl»
0.0
ALKBH7 AlkB homolog 7 Felis catus
TI:9685 None
 
M4F5A7_BRACM
EnsemblPlants»
0.0
Fe2OG dioxygenase domain-containing protein Brassica campestris
TI:3711 None
   
M5VJ71_PRUPE
EnsemblPlants»
0.0
PRUPE_8G258600 Uncharacterized protein Prunus persica
TI:3760 None
 
Q1ECQ5_ARATH
TAIR»
0.0
At4g02485 2-oxoglutarate (2OG) and Fe(II)-dependent
oxygenase superfamily protein (At4g02485)		 Arabidopsis thaliana
TI:3702 None
 
Q2R067_ORYSJ
EnsemblPlants»
0.0
LOC_Os11g43610 Os11g0657200 Os11g0657200 protein (Oxidoreductase, 2OG-Fe oxygenase family protein,
putative, expressed) (cDNA clone:006-211-E11, full insert sequence)		 Oryza sativa
TI:4530 None
 
Q383D9_TRYB2
VEuPathDB»
0.0
Tb11.01.3200 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Trypanosoma brucei
TI:5691 None
 
Q4Q7Z1_LEIMA
EnsemblProtists»
0.0
LMJF_28_2710 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Leishmania major
TI:5664 None
 
Q566X4_DANRE
ZFIN»
0.5
zgc:112404 Alpha-ketoglutarate-dependent dioxygenase alkB
homolog 7, mitochondrial (Zgc:112404)		 Danio rerio
TI:7955 None
 
Q57W43_TRYB2
VEuPathDB»
0.0
Tb05.28F8.370 Fe2OG dioxygenase domain-containing protein Trypanosoma brucei
TI:5691 None
 
Q5KJN7_CRYNJ
EnsemblFungi»
0.0
CNC05880 Fe2OG dioxygenase domain-containing protein Cryptococcus neoformans
TI:5207 None
 
Q7YWP5_CAEEL
WormBase»
0.5
alkb-7 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
Q9GNH7_LEIMA
EnsemblProtists»
0.0
L3377.4 Uncharacterized protein L3377.4 Leishmania major
TI:5664 None
 
Q9VTP1_DROME
FlyBase»
1.5
Dmel\CG14130 IP06473p Drosophila melanogaster
TI:7227 None
 
T1G2N9_HELRO
EnsemblMetazoa»
0.0
20215337 Alpha-ketoglutarate-dependent dioxygenase
AlkB-like domain-containing protein		 Helobdella robusta
TI:6412 None
 
W1P3J5_AMBTC
EnsemblPlants»
0.0
AMTR_s00045p00203370 Fe2OG dioxygenase domain-containing protein Amborella trichopoda
TI:13333 None
 
W5MH42_LEPOC
Ensembl»
0.0
AlkB homolog 7 Lepisosteus oculatus
TI:7918 None
 
YLW2_SCHPO
PomBase»
4.2
SPAP8A3.02c Uncharacterized protein P8A3.02c Schizosaccharomyces pombe
TI:4896 None