Collated Gene Ontology terms

Biological process: membrane insertase activity(2020, 2022, 2025)

Molecular function: protein insertion into ER membrane by stop-transfer membrane-anchor sequence2020, 2024, 2025 tail-anchored membrane protein insertion into ER membrane2020, 2022, 2024, 2025 phospholipid transport2024, 2025 phospholipid metabolic process2024, 2025 apoptotic process2025 protein insertion into ER membrane2020 protein folding in endoplasmic reticulum2019

Cellular component: EMC complex2012, 2020, 2025 endoplasmic reticulum membrane2020, 2024, 2025 membrane2012, 2025 endoplasmic reticulum2009, 2018, 2021, 2025 nucleus2017, 2018 endomembrane system2014

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A8MQD8_ARATH
TAIR»
0.0
At5g10780 ER membrane protein complex subunit 4 Arabidopsis thaliana
TI:3702 None
 
C7FZZ9_DICDI
dictyBase»
0.0
DDB_G0295773 ER membrane protein complex subunit 4 Dictyostelium discoideum
TI:44689 None
 
D4A0W1_RAT
RGD»
1.5
Emc4 ER membrane protein complex subunit 4 Rattus norvegicus
TI:10116 None
   
EMC4_DANRE
ZFIN»
1.5
emc4 ER membrane protein complex
subunit 4 (Transmembrane protein 85)		 Danio rerio
TI:7955 None
 
EMC4_HUMAN
Ensembl»
3.2
EMC4 ER membrane protein complex subunit 4 (Cell
proliferation-inducing gene 17 protein) (Transmembrane protein 85)		 Homo sapiens
TI:9606 None
 
EMC4_MOUSE
Ensembl»
3.0
Emc4 ER membrane protein complex
subunit 4 (Transmembrane protein 85)		 Mus musculus
TI:10090 None
 
EMC4_YEAST
SGD»
3.7
EMC4 ER membrane protein complex subunit 4 Saccharomyces cerevisiae
TI:4932 None
 
Q9N4N3_CAEEL
WormBase»
0.0
perm-3 ER membrane protein complex subunit 4 Caenorhabditis elegans
TI:6239 None
 
Q9VNQ3_DROME
FlyBase»
2.8
EMC4 ER membrane protein complex subunit 4 Drosophila melanogaster
TI:7227 None
 
YQ13_SCHPO
PomBase»
1.0
SPCC1281.03c ER membrane protein complex subunit 4 Schizosaccharomyces pombe
TI:4896 None