Collated Gene Ontology terms

Biological process: metal ion binding(2024) DNA binding(2024) ubiquitin protein ligase activity(2005, 2020, 2024) transferase activity(2024) zinc ion binding(2006, 2014, 2022) ubiquitin-protein transferase activity(2014, 2024) acyltransferase activity, transferring groups other than amino-acyl groups(2024) N-acetyltransferase activity(2005)

Molecular function: snoRNA splicing2013, 2017, 2024 mRNA processing2024 RNA splicing2024 protein ubiquitination2014, 2018, 2024 mRNA splicing, via spliceosome2013, 2015, 2019, 2024 negative regulation of chemokine-mediated signaling pathway2018, 2024 regulation of macromolecule metabolic process2024 generation of catalytic spliceosome for first transesterification step2013, 2024 DNA repair2024 mRNA metabolic process2024
regulation of RNA splicing2015 neuron differentiation2013 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 mRNA cis splicing, via spliceosome2005 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021

Cellular component: U2-type spliceosomal complex2013, 2015, 2017, 2024 nucleus2009, 2012, 2013, 2018, 2019, 2024 spliceosomal complex2013, 2020, 2024 U2-type precatalytic spliceosome2019, 2024 nucleoplasm2022, 2023, 2024 nuclear speck2024 membrane2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 1/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q9VDP8_DROME
FlyBase»
3.6
mdlc CG4973 protein (CG4973-PA)
(LD35003p) (Midlife crisis)		 Drosophila melanogaster
TI:7227 None
 
R113A_HUMAN
Ensembl»
3.7
RNF113A E3 ubiquitin-protein ligase RNF113A (EC 2.3.2.27) (Cwc24 homolog)
(RING finger protein 113A) (Zinc finger protein 183)		 Homo sapiens
TI:9606 None
 
CWC24_YEAST
SGD»
3.5
CWC24 Pre-mRNA-splicing factor CWC24 (Complexed
with CEF1 protein 24)		 Saccharomyces cerevisiae
TI:4932 None
 
CWC24_SCHPO
PomBase»
2.9
cwf24 Pre-mRNA-splicing factor cwf24 (Complexed
with cdc5 protein 24)		 Schizosaccharomyces pombe
TI:4896 None
 
RN113_CAEEL
WormBase»
2.1
rnf-113 Probable E3 ubiquitin-protein ligase rnf113 (EC
2.3.2.27) (RING finger protein 113 homolog)		 Caenorhabditis elegans
TI:6239 None
 
RN113_DICDI
dictyBase»
0.5
rnf113 RING finger protein 113 homolog Dictyostelium discoideum
TI:44689 None
 
Q6DRF0_DANRE
ZFIN»
0.5
wu:fj91a07 RING finger protein 113A
(Zinc finger protein 183-like 1)		 Danio rerio
TI:7955 None
 
R113B_HUMAN
Ensembl»
0.5
RNF113B RING finger protein 113B
(Zinc finger protein 183-like 1)		 Homo sapiens
TI:9606 None
 
A0A178UZR1_ARATH
TAIR»
0.5
At4g01023 RING/U-box superfamily protein Arabidopsis thaliana
TI:3702 None
 
Q5PPN1_RAT
RGD»
2.5
Rnf113a1 Ring finger protein 113A1 Rattus norvegicus
TI:10116 None
 
Q8R3P8_MOUSE
Ensembl»
0.0
Rnf113a1 Ring finger protein 113A1 Mus musculus
TI:10090 None
 
Q14B01_MOUSE
Ensembl»
0.0
Rnf113a2 Ring finger protein 113A2 Mus musculus
TI:10090 None
 
Q67ER1_RAT
RGD»
0.0
Rnf113a2 Ring finger protein 113A2 Rattus norvegicus
TI:10116 None
 
A0A8V0ZLA4_CHICK
Ensembl»
0.0
RNF113B Ring finger protein 113B Gallus gallus
TI:9031 None
   
C3H1_ARATH
TAIR»
0.0
At1g01350 Zinc finger CCCH
domain-containing protein 1 (AtC3H1)		 Arabidopsis thaliana
TI:3702 None
 
C3H51_ARATH
TAIR»
0.0
At5g06420 Zinc finger CCCH
domain-containing protein 51 (AtC3H51)		 Arabidopsis thaliana
TI:3702 None