Collated Gene Ontology terms

Biological process: RNA binding(2014, 2015)

Molecular function: chromatin organization2014, 2019, 2025 regulation of RNA splicing2021, 2025 mRNA processing2025 RNA splicing2025 rhythmic process2025 spermatogenesis2008 response to red light2008 response to blue light2008 regulation of photomorphogenesis2008 regulation of mRNA splicing, via spliceosome2022
regulation of circadian rhythm2008 miRNA processing2017 mRNA cis splicing, via spliceosome2020 ethylene-activated signaling pathway2011 embryonic cranial skeleton morphogenesis2022 central nervous system development2022

Cellular component: nucleus2006, 2008, 2009, 2015, 2018, 2021, 2025 nucleoplasm2015, 2022, 2024, 2025 midbody2024, 2025 intercellular bridge2024, 2025 chromatin2015, 2025

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 12/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
FA50A_HUMAN
Ensembl»
2.4
FAM50A Protein FAM50A (Protein HXC-26) (Protein XAP-5) Homo sapiens
TI:9606 None
 
FA50B_HUMAN
Ensembl»
0.5
FAM50B Protein FAM50B (Protein XAP-5-like) Homo sapiens
TI:9606 None
 
XCT_ORYSJ
EnsemblPlants»
0.0
XCT Protein XAP5 CIRCADIAN TIMEKEEPER Oryza sativa
TI:4530 None
 
B7QFH7_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW012217 Protein FAM50 homolog Ixodes scapularis
TI:6945 None
 
FA50B_MOUSE
Ensembl»
0.5
Fam50b Protein FAM50B (Protein XAP-5-like) Mus musculus
TI:10090 None
 
FAM50_CAEEL
WormBase»
0.5
C47E8.4 Protein FAM50 homolog Caenorhabditis elegans
TI:6239 None
 
XCT_ARATH
TAIR»
5.3
XCT Protein XAP5 CIRCADIAN TIMEKEEPER Arabidopsis thaliana
TI:3702 None
 
A0A078FNA0_BRANA
euHCVdb»
0.0
BnaA09g43400D (rape) hypothetical
protein (BnaA09g43400D protein)		 Brassica napus
TI:3708 None
 
A0A159YK42_CHLRE
euHCVdb»
0.0
XAP5 X-chromosome-associated protein 5 Chlamydomonas reinhardtii
TI:3055 None
 
A0A251S9W4_HELAN
euHCVdb»
0.0
XCT Putative XAP5 family protein (XAP5 protein) Helianthus annuus
TI:4232 None
 
B7ZYJ9_MAIZE
EnsemblPlants»
0.0
LOC100279523 Protein XAP5 CIRCADIAN TIMEKEEPER Zea mays
TI:4577 None
 
F50AA_XENLA
AG»
0.0
fam50a-a Protein FAM50A-A Xenopus laevis
TI:8355 None
 
FA50A_MOUSE
Ensembl»
1.0
Fam50a Protein FAM50A (Protein XAP-5) Mus musculus
TI:10090 None
 
FA50A_XENTR
AG»
0.0
fam50a Protein FAM50A Xenopus tropicalis
TI:8364 None
 
FAM50_DROME
FlyBase»
1.0
CG12259 Protein FAM50 homolog Drosophila melanogaster
TI:7227 None
 
G7LAJ6_MEDTR
EnsemblPlants»
0.0
11410133 Putative XAP5 protein
(XAP5 circadian timekeeper)		 Medicago truncatula
TI:3880 None
 
H2QZA9_PANTR
Ensembl»
0.0
FAM50A Family with sequence similarity 50 member A
(Family with sequence similarity 50, member A)		 Pan troglodytes
TI:9598 None
 
K3ZV31_SETIT
EnsemblPlants»
0.0
LOC101774542 FAM50A/XAP5 C-terminal domain-containing protein Setaria italica
TI:4555 None
 
M5VRD1_PRUPE
euHCVdb»
0.0
PRUPE_7G010600 FAM50A/XAP5 C-terminal domain-containing protein Prunus persica
TI:3760 None
 
T1G1D2_HELRO
EnsemblMetazoa»
0.0
20214880 FAM50A/XAP5 C-terminal domain-containing protein Helobdella robusta
TI:6412 None
 
W5NBA0_LEPOC
Ensembl»
0.0
Family with sequence similarity 50 member A Lepisosteus oculatus
TI:7918 None
 
A0A061E0B7_THECC
neXtProt»
0.0
TCM_006691 Xap5 circadian timekeeper isoform 1 Theobroma cacao
TI:3641 None
 
A0A067E465_CITSI
euHCVdb»
0.0
CISIN_1g0193851mg FAM50A/XAP5 C-terminal domain-containing protein Citrus sinensis
TI:2711 None
 
A0A067E4K9_CITSI
euHCVdb»
0.0
CISIN_1g0193852mg Uncharacterized protein Citrus sinensis
TI:2711 None
 
A0A078FU58_BRANA
euHCVdb»
0.0
BnaA04g11980D BnaA04g11980D protein Brassica napus
TI:3708 None
 
A0A0A0LM87_CUCSA
neXtProt»
0.0
Csa_2G263920 FAM50A/XAP5 C-terminal domain-containing protein Cucumis sativus
TI:3659 None
 
A0A0K9P157_ZOSMR
neXtProt»
0.0
ZOSMA_44G01040 Xap5,circadian timekeeper Zostera marina
TI:29655 None
 
A0A1W0W5Y3_SORBI
neXtProt»
0.0
SORBI_3002G277600 FAM50A/XAP5 C-terminal domain-containing protein Sorghum bicolor
TI:4558 None
 
A0A1Y1HYC5_KLENI
euHCVdb»
0.0
KFL_000640250 FAM50A/XAP5 C-terminal domain-containing protein Klebsormidium nitens
TI:105231 None
 
A0A2C9V192_MANES
euHCVdb»
0.0
MANES_11G090000v8 FAM50A/XAP5 C-terminal domain-containing protein Manihot esculenta
TI:3983 None
 
A0A2C9W0J2_MANES
neXtProt»
0.0
MANES_04G078200v8 FAM50A/XAP5 C-terminal domain-containing protein Manihot esculenta
TI:3983 None
 
A0A2G2Y2K1_CAPAN
neXtProt»
0.0
T459_32097 Protein XAP5 CIRCADIAN TIMEKEEPER Capsicum annuum
TI:4072 None
 
A0A2K1L152_PHYPA
EnsemblPlants»
0.0
LOC112278748 FAM50A/XAP5 C-terminal domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A2R6XGH2_MARPO
euHCVdb»
0.0
MARPO_0015s0022 FAM50A/XAP5 C-terminal domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A7I4B823_PHYPA
EnsemblPlants»
0.0
LOC112294169 FAM50A/XAP5 C-terminal domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A7U2FAY3_PHANO
TubercuList»
0.0
JI435_150430 FAM50A/XAP5 C-terminal domain-containing protein Phaeosphaeria nodorum
TI:13684 None
 
A0A804IU74_MUSAM
EnsemblPlants»
0.0
GSMUA_132650.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A9R1UJL4_LACSA
neXtProt»
0.0
LSAT_V11C900481550 FAM50A/XAP5 C-terminal domain-containing protein Lactuca sativa
TI:4236 None
 
A0A9R1XFF1_LACSA
euHCVdb»
0.0
LSAT_V11C500287970 FAM50A/XAP5 C-terminal domain-containing protein Lactuca sativa
TI:4236 None
 
A0A9R1XQA4_LACSA
neXtProt»
0.0
LSAT_V11C300119940 FAM50A/XAP5 C-terminal domain-containing protein Lactuca sativa
TI:4236 None
 
A0BZV5_PARTE
euHCVdb»
0.0
GSPATT00005924001 FAM50A/XAP5 C-terminal domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0D9X7_PARTE
euHCVdb»
0.0
GSPATT00014776001 FAM50A/XAP5 C-terminal domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0DWQ0_PARTE
euHCVdb»
0.0
GSPATT00021110001 FAM50A/XAP5 C-terminal domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0E3H5_PARTE
euHCVdb»
0.0
GSPATT00023015001 FAM50A/XAP5 C-terminal domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A7F8X0_SCLS1
TubercuList»
0.0
SS1G_14051 FAM50A/XAP5 C-terminal domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A9V9G2_MONBE
euHCVdb»
0.0
MONBRDRAFT_28793 FAM50A/XAP5 C-terminal domain-containing protein Monosiga brevicollis
TI:81824 None
 
B3S3V0_TRIAD
CTD»
0.0
TRIADDRAFT_28870 FAM50A/XAP5 C-terminal domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B6K6G2_SCHJY
TubercuList»
0.0
xap5 Xap-5-like protein Schizosaccharomyces japonicus
TI:4897 None
 
B8C484_THAPS
euHCVdb»
0.0
THAPSDRAFT_23226 FAM50A/XAP5 C-terminal domain-containing protein Thalassiosira pseudonana
TI:35128 None
 
B9H152_POPTR
euHCVdb»
0.0
POPTR_004G168400 FAM50A/XAP5 C-terminal domain-containing protein Populus trichocarpa
TI:3694 None
 
B9HRA8_POPTR
euHCVdb»
0.0
POPTR_009G129700 FAM50A/XAP5 C-terminal domain-containing protein Populus trichocarpa
TI:3694 None
 
B9STC7_RICCO
euHCVdb»
0.0
RCOM_0660610 Protein FAM50A, putative Ricinus communis
TI:3988 None
 
D6WTJ7_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_08623 Protein FAM50 homolog Tribolium castaneum
TI:7070 None
 
D7U5A2_VITVI
neXtProt»
0.0
VIT_03s0038g01810 FAM50A/XAP5 C-terminal domain-containing protein Vitis vinifera
TI:29760 None
 
D8REB9_SELML
euHCVdb»
0.0
SELMODRAFT_170698 FAM50A/XAP5 C-terminal domain-containing protein Selaginella moellendorffii
TI:88036 None
 
D8RHV8_SELML
euHCVdb»
0.0
SELMODRAFT_94249 FAM50A/XAP5 C-terminal domain-containing protein Selaginella moellendorffii
TI:88036 None
 
D8SL86_SELML
euHCVdb»
0.0
SELMODRAFT_120045 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
D8STP0_SELML
euHCVdb»
0.0
SELMODRAFT_124535 FAM50A/XAP5 C-terminal domain-containing protein Selaginella moellendorffii
TI:88036 None
 
E3L293_PUCGT
TubercuList»
0.0
PGTG_16694 FAM50A/XAP5 C-terminal domain-containing protein Puccinia graminis
TI:5297 None
 
E9GK72_DAPPU
neXtProt»
0.0
DAPPUDRAFT_51776 Protein FAM50 homolog Daphnia pulex
TI:6669 None
 
E9HH81_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_62813 Protein FAM50 homolog Daphnia pulex
TI:6669 None
 
F0ZS53_DICPU
TubercuList»
0.0
DICPUDRAFT_37066 FAM50A/XAP5 C-terminal domain-containing protein Dictyostelium purpureum
TI:5786 None
 
F2D6Q5_HORVV
EnsemblPlants»
0.0
LOC123400119 Predicted protein Hordeum vulgare
TI:4513 None
 
F4P0I9_BATDJ
euHCVdb»
0.0
BATDEDRAFT_24147 FAM50A/XAP5 C-terminal domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F50AB_XENLA
AG»
0.0
fam50a-b Protein FAM50A-B Xenopus laevis
TI:8355 None
 
F6VCG5_CIOIN
Ensembl»
0.0
FAM50A/XAP5 C-terminal domain-containing protein Ciona intestinalis
TI:7719 None
 
FA50A_DANRE
ZFIN»
2.9
fam50a Protein FAM50A Danio rerio
TI:7955 None
 
FAM50_ANOGA
EnsemblMetazoa»
0.0
AGAP002062 Protein FAM50 homolog Anopheles gambiae
TI:7165 None
 
FAM50_CAEBR
WormBase»
0.0
CBG04561 Protein FAM50 homolog Caenorhabditis briggsae
TI:6238 None
 
FAM50_DICDI
dictyBase»
0.5
fam50 Protein FAM50 homolog Dictyostelium discoideum
TI:44689 None
 
FAM50_SCHPO
PomBase»
1.8
xap5 FAM50 family protein C1020.12c Schizosaccharomyces pombe
TI:4896 None
 
G3RCC8_GORGO
Ensembl»
0.0
FAM50A FAM50A/XAP5 C-terminal domain-containing protein Gorilla gorilla
TI:9593 None
 
G7MQH3_MACMU
Ensembl»
0.0
FAM50B Family with sequence similarity
50 member B (Protein FAM50B)		 Macaca mulatta
TI:9544 None
 
H3G8I1_PHYRM
EnsemblProtists»
0.0
FAM50A/XAP5 C-terminal domain-containing protein Phytophthora ramorum
TI:164328 None
 
I1IS85_BRADI
EnsemblPlants»
0.0
LOC100829960 FAM50A/XAP5 C-terminal domain-containing protein Brachypodium distachyon
TI:15368 None
 
I1K5R0_SOYBN
EnsemblPlants»
0.0
LOC100810412 FAM50A/XAP5 C-terminal domain-containing protein Glycine max
TI:3847 None
 
I1KQ65_SOYBN
EnsemblPlants»
0.0
LOC100814574 FAM50A/XAP5 C-terminal domain-containing protein Glycine max
TI:3847 None
 
M4EQU2_BRACM
EnsemblPlants»
0.0
BRAPAZ1V2_A09P71090.2 FAM50A/XAP5 C-terminal domain-containing protein Brassica campestris
TI:3711 None
 
Q4WM96_ASPFU
TubercuList»
0.0
AFUA_6G10680 XAP5 domain protein Aspergillus fumigatus
TI:746128 None
 
Q5BAJ6_EMENI
TubercuList»
0.0
ANIA_02434 XAP5 domain
protein (AFU_orthologue AFUA_6G10680)		 Emericella nidulans
TI:162425 None
 
Q5KGP1_CRYD1
TubercuList»
0.0
CNE02860 FAM50A/XAP5 C-terminal domain-containing protein Cryptococcus deneoformans
TI:40410 None
 
Q6C2N0_YARLI
TubercuList»
0.0
YALI0_F06490g YALI0F06490p Yarrowia lipolytica
TI:4952 None
 
Q7SBF2_NEUCR
TubercuList»
0.0
NCU07604 XAP5 domain-containing protein Neurospora crassa
TI:5141 None
 
Q8I3G2_PLAF7
TubercuList»
0.0
PF3D7_0530600 XAP-5 DNA binding protein, putative Plasmodium falciparum
TI:5833 None
 
W1Q0H4_AMBTC
euHCVdb»
0.0
AMTR_s00041p00202860 FAM50A/XAP5 C-terminal domain-containing protein Amborella trichopoda
TI:13333 None
 
A0A1S3XX52_TOBAC
euHCVdb»
0.0
LOC107769723 Protein XAP5 CIRCADIAN TIMEKEEPER Nicotiana tabacum
TI:4097 None
   
A0A1U8B7C5_NELNU
neXtProt»
0.0
LOC104607814 Protein XAP5 CIRCADIAN TIMEKEEPER isoform X1 Nelumbo nucifera
TI:4432 None
   
A0A1U8JRM0_GOSHI
neXtProt»
0.0
LOC107908671 Protein XAP5 CIRCADIAN TIMEKEEPER isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A2I4EWY5_JUGRE
euHCVdb»
0.0
LOC108993434 Protein XAP5 CIRCADIAN TIMEKEEPER-like Juglans regia
TI:51240 None
   
A0A2I4GC24_JUGRE
euHCVdb»
0.0
LOC109006571 Protein XAP5 CIRCADIAN TIMEKEEPER-like Juglans regia
TI:51240 None
   
A0A3Q2HLB3_HORSE
Ensembl»
0.0
FAM50A Family with sequence similarity 50 member A Equus caballus
TI:9796 None
   
A0A5F8H994_MONDO
Ensembl»
0.0
FAM50A FAM50A/XAP5 C-terminal domain-containing protein Monodelphis domestica
TI:13616 None
   
A0A5G2QKU3_PIG
Ensembl»
0.0
FAM50A Family with sequence similarity 50 member A Sus scrofa
TI:9823 None
   
A0A5K1UVZ5_MACMU
Ensembl»
0.0
FAM50A Family with sequence similarity 50 member A Macaca mulatta
TI:9544 None
   
A0A7M7PVE9_STRPU
EnsemblMetazoa»
0.0
FAM50A/XAP5 C-terminal domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3PZL2_CANLF
Ensembl»
0.0
FAM50A Family with sequence similarity 50 member A Canis lupus
TI:9612 None
   
A0A8R1ZCB0_PRIPA
EnsemblMetazoa»
0.0
WBGene00305017 Protein FAM50 homolog Pristionchus pacificus
TI:54126 None
   
A0A9J7L6X5_BRAFL
euHCVdb»
0.0
LOC118416468 Protein FAM50A-like Branchiostoma floridae
TI:7739 None
   
A0A9J7MSF1_BRAFL
neXtProt»
0.0
LOC118416901 Protein FAM50 homolog Branchiostoma floridae
TI:7739 None
   
A0A9R0JTT0_SPIOL
euHCVdb»
0.0
LOC110786515 Protein XAP5 CIRCADIAN TIMEKEEPER Spinacia oleracea
TI:3562 None
   
A0ABI7VTU7_FELCA
Ensembl»
0.0
FAM50A FAM50A/XAP5 C-terminal domain-containing protein Felis catus
TI:9685 None
   
A0ABI7Z7X1_FELCA
Ensembl»
0.0
FAM50B FAM50A/XAP5 C-terminal domain-containing protein Felis catus
TI:9685 None
   
A0ABM3AVV3_GOSHI
euHCVdb»
0.0
LOC107927818 Protein XAP5 CIRCADIAN TIMEKEEPER isoform X1 Gossypium hirsutum
TI:3635 None
   
A0ABM3QQX7_SPIOL
neXtProt»
0.0
LOC110800694 Protein XAP5 CIRCADIAN TIMEKEEPER-like Spinacia oleracea
TI:3562 None
   
D3Z9C2_RAT
RGD»
0.5
Fam50b Family with sequence similarity 50, member B Rattus norvegicus
TI:10116 None
   
E1BDX9_BOVIN
Ensembl»
0.0
FAM50A Family with sequence similarity 50 member A Bos taurus
TI:9913 None
   
F7AUE4_ORNAN
Ensembl»
0.0
FAM50A Family with sequence similarity 50 member A Ornithorhynchus anatinus
TI:9258 None
   
F7CAW0_HORSE
Ensembl»
0.0
FAM50B Family with sequence similarity 50 member B Equus caballus
TI:9796 None
   
G1KDX7_ANOCA
Ensembl»
0.0
fam50a FAM50A/XAP5 C-terminal domain-containing protein Anolis carolinensis
TI:28377 None
   
G3V9M8_RAT
RGD»
1.0
Fam50a Family with sequence similarity 50, member A Rattus norvegicus
TI:10116 None
   
H2L7Y9_ORYLA
Ensembl»
0.0
FAM50A Family with sequence similarity 50 member A Oryzias latipes
TI:8090 None
   
I3LCK4_PIG
Ensembl»
0.0
FAM50B Family with sequence similarity 50 member B Sus scrofa
TI:9823 None
   
M0ZMX9_SOLTU
EnsemblPlants»
0.0
LOC102584555 Protein FAM50A Solanum tuberosum
TI:4113 None
   
M4ENE8_BRACM
EnsemblPlants»
0.0
FAM50A/XAP5 C-terminal domain-containing protein Brassica campestris
TI:3711 None
   
W5FJN7_WHEAT
EnsemblPlants»
0.0
LOC123104580 FAM50A/XAP5 C-terminal domain-containing protein Triticum aestivum
TI:4565 None