Unknome v3

Cluster UKP01333
PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE
Standard knownness: 17.8; Custom knownness: None; Num. species: 94; Orthology database: Panther19.0; Protein members: 699

Collated Gene Ontology terms

Biological process: 1-phosphatidylinositol-4-phosphate 5-kinase activity^{(2005, 2006, 2007, 2008, 2009, 2010, 2011, 2013, 2014, 2015, 2016, 2018, 2019, 2020, 2022, 2023, 2024)} kinase activity⁽²⁰²⁴⁾ ATP binding^{(2019, 2020, 2024)} phosphatidylinositol kinase activity^{(2006, 2023, 2024)} 1-phosphatidylinositol-5-phosphate 4-kinase activity^{(2020, 2022, 2023, 2024)} protein homodimerization activity^{(2016, 2020, 2024)} GTP binding^{(2020, 2024)} identical protein binding⁽²⁰²⁴⁾ kinase binding^{(2010, 2024)} calcium ion binding⁽²⁰²⁴⁾
transmembrane signaling receptor activity²⁰²⁴ phospholipid binding^{2020, 2024} phosphatidylinositol-4-phosphate binding^{2012, 2017, 2024} phosphatidylinositol-3-phosphate binding^{2012, 2017, 2024} metal ion binding²⁰²⁴ 1-phosphatidylinositol-3-phosphate 4-kinase activity^{2018, 2024} G protein-coupled receptor activity²⁰²⁴ 1-phosphatidylinositol-3-phosphate 5-kinase activity²⁰²⁴ protein kinase regulator activity^{2022, 2024} 1-phosphatidylinositol-5-kinase activity²⁰²⁴ talin binding²⁰¹³ phosphatidylserine binding²⁰¹² phosphatidylinositol-5-phosphate binding²⁰¹² mRNA 3'-UTR binding²⁰²¹ lipid kinase activity²⁰¹⁷ diacylglycerol binding²⁰⁰⁶ calmodulin binding²⁰¹⁰ actin monomer binding²⁰⁰⁷ actin filament binding²⁰⁰⁷

Molecular function: phosphatidylinositol metabolic process^{2004, 2009, 2011, 2012, 2015, 2024} phosphorylation²⁰²⁴ phosphatidylinositol phosphate biosynthetic process^{2013, 2019, 2023, 2024} 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process^{2020, 2022, 2024} regulation of autophagy^{2015, 2020, 2024} negative regulation of insulin receptor signaling pathway^{2019, 2020, 2024} positive regulation of autophagosome assembly^{2017, 2024} autophagosome-lysosome fusion^{2020, 2024} lipid metabolic process²⁰²⁴ phosphatidylinositol biosynthetic process^{2005, 2016, 2024}
vesicle-mediated cholesterol transport^{2020, 2024} megakaryocyte development^{2011, 2024} positive regulation of apoptotic process^{2019, 2024} negative regulation of mitochondrial membrane potential^{2019, 2024} actin cytoskeleton organization^{2011, 2012, 2014, 2024} negative regulation of cell migration^{2018, 2024} cell surface receptor signaling pathway^{2003, 2024} ruffle assembly^{2011, 2024} protein localization to plasma membrane^{2012, 2024} negative regulation of protein phosphorylation^{2018, 2024} focal adhesion assembly^{2011, 2024} cell chemotaxis^{2011, 2024} phospholipid biosynthetic process^{2010, 2024} fibroblast migration^{2011, 2024} activation of GTPase activity^{2011, 2024} phagocytosis^{2012, 2024} regulation of postsynaptic neurotransmitter receptor internalization²⁰²⁴ regulation of mitotic cytokinesis²⁰²⁴ cortical actin cytoskeleton organization^{2009, 2014, 2024} clathrin-dependent endocytosis^{2011, 2012, 2024} G protein-coupled receptor signaling pathway^{2007, 2024} signal transduction^{2006, 2007, 2014} regulation of synaptic vesicle endocytosis²⁰²⁴ regulation of protein kinase B signaling²⁰²⁴ pollen tube growth²⁰⁰⁹ exocytosis²⁰²⁴ endocytosis^{2009, 2015} chemotaxis²⁰²⁴ cell adhesion²⁰²⁴ carbohydrate metabolic process^{2007, 2024} ascospore-type prospore assembly^{2013, 2024} amino acid metabolic process^{2007, 2024} regulation of muscle organ development^{2017, 2024} regulation of Ras protein signal transduction^{2015, 2024} protein localization^{2014, 2015} pollen germination²⁰⁰⁹ platelet aggregation²⁰¹³ plant-type cell wall modification²⁰⁰⁹ chemotaxis to cAMP^{2015, 2024} axonogenesis²⁰⁰⁸ synaptic vesicle exocytosis²⁰¹² synaptic vesicle endocytosis²⁰¹² stomatal movement²⁰⁰⁷ spermatid development²⁰¹⁰ sorocarp development²⁰⁰⁷ root hair initiation²⁰¹⁶ root hair elongation²⁰⁰⁸ root hair cell tip growth²⁰⁰⁸ regulation of mitotic spindle elongation²⁰¹⁵ regulation of establishment of cell polarity²⁰¹⁶ regulation of TOR signaling²⁰¹³ positive regulation of phagocytosis²⁰¹² positive regulation of multicellular organism growth²⁰¹³ positive regulation of defense response to bacterium²⁰¹² positive regulation of cell growth²⁰¹³ positive gravitropism²⁰¹¹ piecemeal microautophagy of the nucleus²⁰²¹ oocyte microtubule cytoskeleton polarization²⁰⁰⁹ oocyte dorsal/ventral axis specification²⁰¹⁷ neutrophil chemotaxis²⁰¹² negative regulation of protein kinase B signaling²⁰²³ negative regulation of clathrin-dependent endocytosis²⁰¹⁷ membrane organization²⁰²⁴ lateral root formation²⁰¹¹ keratinocyte differentiation²⁰¹² invasive filamentous growth²⁰¹⁴ glycerophospholipid metabolic process²⁰⁰⁶ flower development²⁰²⁴ establishment of tissue polarity²⁰⁰⁹ endosome organization²⁰²¹ dynein-driven meiotic oscillatory nuclear movement²⁰¹⁹ developmental process involved in reproduction²⁰¹⁰ defense response²⁰²⁴ cell-cell adhesion²⁰¹² cell migration²⁰¹⁰ cell division²⁰²⁴ cell differentiation²⁰²⁴ basement membrane organization²⁰¹⁴ autophagy of mitochondrion²⁰²¹ aggregation involved in sorocarp development²⁰⁰⁶ adherens junction assembly²⁰¹²

Cellular component: plasma membrane^{2007, 2010, 2011, 2014, 2016, 2017, 2020, 2021, 2022, 2023, 2024} membrane^{2007, 2014, 2024} cytosol^{2007, 2011, 2013, 2016, 2020, 2023, 2024} cytoplasm^{2008, 2024} nucleus^{2006, 2007, 2010, 2011, 2013, 2020, 2024} autophagosome^{2015, 2024} nucleoplasm^{2016, 2023, 2024} lysosome^{2020, 2024} endoplasmic reticulum²⁰²⁴ cell projection^{2005, 2024}
uropod^{2011, 2012, 2024} ruffle membrane^{2011, 2024} nuclear speck^{2010, 2012, 2024} lamellipodium^{2010, 2024} intracellular membrane-bounded organelle²⁰²⁴ mRNA cleavage and polyadenylation specificity factor complex^{2010, 2024} apical plasma membrane^{2008, 2009, 2011, 2014, 2024} endomembrane system²⁰²⁴ pollen tube^{2011, 2024} focal adhesion^{2012, 2014, 2024} endosome membrane^{2017, 2024} postsynaptic density²⁰²⁴ photoreceptor outer segment²⁰²⁴ photoreceptor inner segment²⁰²⁴ glutamatergic synapse²⁰²⁴ cell division site^{2022, 2024} ruffle²⁰²⁴ phagocytic cup²⁰²⁴ endoplasmic reticulum membrane²⁰²⁴ ciliary pocket^{2015, 2018} anchoring junction²⁰²⁴ adherens junction²⁰²⁴ cell cortex^{2009, 2024} site of polarized growth²⁰¹⁴ presynaptic endocytic zone membrane²⁰²⁴ presynapse²⁰²⁴ phagolysosome membrane²⁰¹² motile cilium²⁰²⁴ male germline ring canal²⁰¹⁰ late endosome membrane²⁰¹² extracellular exosome²⁰¹⁴ endosome²⁰⁰⁷ early endosome²⁰¹⁷ chromosome²⁰²⁴

Phylogenetic distribution

Chordates:	22/21
Echinoderms:	0/0
Hemichordates:	1/1
Annelids:	1/1
Molluscs:	0/0
Bryozoans:	0/0
Platyhelminthes:	0/0
Rotifers:	0/0
Nematodes:	3/3
Arthropods:	5/5
Tardigrades:	0/0
Placozoa:	1/1
Cnidaria:	1/1
Porifera:	0/0
Choanoflagellates+:	12/1
Dikarya:	0/14
Fungi (other):	0/1
Protozoa:	3/3
Excavates:	4/4
Harosa:	4/4
Hacrobia:	0/0
Plants:	37/39
Archea:	0/8
Bacteria:	0/35

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Protein sequences (FASTA format)

Knownness history

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Proteins

UniProt ID
Organism DB»

Species [Show all]

A0A8V0YT91_CHICK
Ensembl»

0.0

PIP5K1B

Phosphatidylinositol-4-phosphate 5-kinase
type 1 beta

Gallus gallus
TI:9031 None

A0A8V1AJC3_CHICK
Ensembl»

0.0

PIP5K1C

Phosphatidylinositol-4-phosphate 5-kinase,
type I, gamma

Gallus gallus
TI:9031 None

A0A8V1ALV9_CHICK
Ensembl»

0.0

PIP5K1A

Phosphatidylinositol-4-phosphate 5-kinase
type 1 alpha

Gallus gallus
TI:9031 None

PI5K7_ARATH
TAIR»

0.0

PIP5K7

Phosphatidylinositol 4-phosphate 5-kinase 7 (AtPIP5K7) (EC 2.7.1.68) (1-phosphatidylinositol
4-phosphate kinase 7) (Diphosphoinositide kinase 7) (AtP5K2) (PtdIns(4)P-5-kinase 7)

Arabidopsis thaliana
TI:3702 None

PI5KA_ARATH
TAIR»

0.0

PIP5K10

Phosphatidylinositol 4-phosphate 5-kinase 10 (AtPIP5K10) (EC 2.7.1.68) (1-phosphatidylinositol
4-phosphate kinase 10) (Diphosphoinositide kinase 10) (PtdIns(4)P-5-kinase 10)

Arabidopsis thaliana
TI:3702 None

PIPSL_HUMAN
AG»

1.0

PIPSL

Putative PIP5K1A and
PSMD4-like protein (PIP5K1A-PSMD4)

Homo sapiens
TI:9606 None

A0A8V0ZWL6_CHICK
Ensembl»

0.0

PIP4K2C

Phosphatidylinositol-5-phosphate 4-kinase
type 2 gamma

Gallus gallus
TI:9031 None

PI5KB_ARATH
TAIR»

0.8

PIP5K11

Putative phosphatidylinositol 4-phosphate 5-kinase 11 (AtPIP5K11) (EC 2.7.1.68)
(1-phosphatidylinositol 4-phosphate kinase 11) (Diphosphoinositide kinase 11) (PtdIns(4)P-5-kinase 11)

Arabidopsis thaliana
TI:3702 None

A0A8M2BIV4_DANRE
CTD»

1.0

si:ch211-243a15.1

Phosphatidylinositol 4-phosphate 5-kinase
type-1 gamma isoform X1

Danio rerio
TI:7955 None

A0A8M3AUW9_DANRE
CTD»

1.0

pip5k1bb

Phosphatidylinositol-4-phosphate 5-kinase type-1
beta isoform X1

Danio rerio
TI:7955 None

A0A8M3B5L6_DANRE
CTD»

1.0

pip5k1ca

Phosphatidylinositol 4-phosphate 5-kinase
type-1 gamma isoform X1

Danio rerio
TI:7955 None

A0A8M3BCW3_DANRE
CTD»

1.0

pip5k1ba

Phosphatidylinositol 4-phosphate 5-kinase
type-1 beta isoform X1

Danio rerio
TI:7955 None

A0A8M9Q466_DANRE
CTD»

1.0

pip5kl1

Phosphatidylinositol 4-phosphate 5-kinase-like
protein 1 isoform X1

Danio rerio
TI:7955 None

Q54M96_DICDI
dictyBase»

1.0

DDB_G0286115

Phosphatidylinositol-4-phosphate 5-kinase
family protein

Dictyostelium discoideum
TI:44689 None

Q54VR4_DICDI
dictyBase»

1.0

DDB_G0280377

Uncharacterized protein

Dictyostelium discoideum
TI:44689 None

Q556H0_DICDI
dictyBase»

1.0

DDB_G0272638 DDB_G0274067

Phosphatidylinositol-4-phosphate 5-kinase
family protein

Dictyostelium discoideum
TI:44689 None

A0A6M3Q9L5_DROME
FlyBase»

1.0

PIP5K59B

Phosphatidylinositol 4-phosphate 5-kinase 59B,
isoform G (EC 2.7.1.68)

Drosophila melanogaster
TI:7227 None

A0A8V0XM27_CHICK
Ensembl»

0.0

PIP4K2A

Phosphatidylinositol-5-phosphate 4-kinase
type 2 alpha

Gallus gallus
TI:9031 None

PI5K8_ARATH
TAIR»

1.0

PIP5K8

Phosphatidylinositol 4-phosphate 5-kinase 8 (AtPIP5K8) (EC 2.7.1.68) (1-phosphatidylinositol
4-phosphate kinase 8) (Diphosphoinositide kinase 8) (PtdIns(4)P-5-kinase 8)

Arabidopsis thaliana
TI:3702 None

Q54DL4_DICDI
dictyBase»

1.5

DDB_G0292190

PIPK domain-containing protein

Dictyostelium discoideum
TI:44689 None

A0A8M9PD30_DANRE
CTD»

2.6

pip5k1ab

Phosphatidylinositol 4-phosphate 5-kinase
type-1 alpha isoform X1

Danio rerio
TI:7955 None

PI5K1_ARATH
TAIR»

2.4

PIP5K1

Phosphatidylinositol 4-phosphate 5-kinase 1 (AtPIP5K1) (EC 2.7.1.68) (1-phosphatidylinositol
4-phosphate kinase 1) (Diphosphoinositide kinase 1) (PtdIns(4)P-5-kinase 1)

Arabidopsis thaliana
TI:3702 None

PI5K6_ARATH
TAIR»

1.6

PIP5K6

Phosphatidylinositol 4-phosphate 5-kinase 6 (AtPIP5K6) (EC 2.7.1.68) (1-phosphatidylinositol
4-phosphate kinase 6) (Diphosphoinositide kinase 6) (PtdIns(4)P-5-kinase 6)

Arabidopsis thaliana
TI:3702 None

Q9BL73_CAEEL
WormBase»

2.3

ppk-2

PIPK domain-containing protein

Caenorhabditis elegans
TI:6239 None

F1QRI7_DANRE
ZFIN»

1.5

pip4k2cb

Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like isoform
X1 (Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b)

Danio rerio
TI:7955 None

PI5K9_ARATH
TAIR»

1.6

PIP5K9

Phosphatidylinositol 4-phosphate 5-kinase 9 (AtPIP5K9) (EC 2.7.1.68) (1-phosphatidylinositol
4-phosphate kinase 9) (Diphosphoinositide kinase 9) (PtdIns(4)P-5-kinase 9)

Arabidopsis thaliana
TI:3702 None

Q503I3_DANRE
ZFIN»

3.4

pip5k1a

Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase,
type I, alpha) (Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a)

Danio rerio
TI:7955 None

A0A8M2BAK4_DANRE
CTD»

1.5

pip4k2ab

Phosphatidylinositol 5-phosphate 4-kinase
type-2 alpha isoform X1

Danio rerio
TI:7955 None

O01759_CAEEL
WormBase»

4.2

ppk-1

PIPK domain-containing protein

Caenorhabditis elegans
TI:6239 None

PI5K2_ARATH
TAIR»

3.2

PIP5K2

Phosphatidylinositol 4-phosphate 5-kinase 2 (AtPIP5K2) (EC 2.7.1.68) (1-phosphatidylinositol
4-phosphate kinase 2) (Diphosphoinositide kinase 2) (PtdIns(4)P-5-kinase 2)

Arabidopsis thaliana
TI:3702 None

Q86A02_DICDI
dictyBase»

3.4

PIPkinA

Ankyrin repeat-containing protein

Dictyostelium discoideum
TI:44689 None

PI5K5_ARATH
TAIR»

4.0

PIP5K5

Phosphatidylinositol 4-phosphate 5-kinase 5 (AtPIP5K5) (EC 2.7.1.68) (1-phosphatidylinositol
4-phosphate kinase 5) (Diphosphoinositide kinase 5) (PtdIns(4)P-5-kinase 5)

Arabidopsis thaliana
TI:3702 None

Y7588_DICDI
dictyBase»

5.5

DDB_G0267588

Probable phosphatidylinositol phosphate
kinase DDB_G0267588 (EC 2.7.1.-)

Dictyostelium discoideum
TI:44689 None

B3DJ34_DANRE
ZFIN»

3.1

LOC560360

Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (Phosphatidylinositol-5-phosphate 4-kinase,
type II, alpha a) (Similar to type II phosphatidylinositolphosphate kinase-alpha)

Danio rerio
TI:7955 None

PI42C_DANRE
ZFIN»

2.5

pip4k2c

Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate
4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)

Danio rerio
TI:7955 None

PI51B_CHICK
CTD»

1.5

PIP5K1B

Phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1-beta) (PtdIns(4)P-5-kinase 1 beta) (EC 2.7.1.68) (Phosphatidylinositol
4-phosphate 5-kinase type I beta) (PIP5KIbeta) (Type I phosphatidylinositol 4-phosphate 5-kinase beta)

Gallus gallus
TI:9031 None

PI5K3_ARATH
TAIR»

4.0

PIP5K3

Phosphatidylinositol 4-phosphate 5-kinase 3 (AtPIP5K3) (EC 2.7.1.68) (1-phosphatidylinositol
4-phosphate kinase 3) (Diphosphoinositide kinase 3) (PtdIns(4)P-5-kinase 3)

Arabidopsis thaliana
TI:3702 None

MSS4_YEAST
SGD»

5.8

MSS4

Phosphatidylinositol 4-phosphate 5-kinase MSS4 (EC 2.7.1.68)
(1-phosphatidylinositol 4-phosphate kinase) (Diphosphoinositide kinase) (PIP5K)

Saccharomyces cerevisiae
TI:4932 None

PI51B_MOUSE
Ensembl»

3.2

Pip5k1b

Phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5KI-beta) (PtdIns(4)P-5-kinase 1 beta) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol
4-phosphate 5-kinase beta) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha) (Phosphatidylinositol 4-phosphate 5-kinase type I beta) (PIP5KIbeta)

Mus musculus
TI:10090 None

PI5L1_HUMAN
Ensembl»

4.2

PIP5KL1

Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 (PI(4)P 5-kinase-like
protein 1) (PtdIns(4)P-5-kinase-like protein 1) (EC 2.7.1.68)

Homo sapiens
TI:9606 None

PI5L1_MOUSE
Ensembl»

1.8

Pip5kl1

Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 (PI(4)P 5-kinase-like protein
1) (PtdIns(4)P-5-kinase-like protein 1) (Phosphatidylinositol phosphate kinase homolog) (PIPKH)

Mus musculus
TI:10090 None

PI5K4_ARATH
TAIR»

7.2

PIP5K4

Phosphatidylinositol 4-phosphate 5-kinase 4 (AtPIP5K4) (EC 2.7.1.68) (1-phosphatidylinositol
4-phosphate kinase 4) (Diphosphoinositide kinase 4) (PtdIns(4)P-5-kinase 4)

Arabidopsis thaliana
TI:3702 None

PI51B_RAT
RGD»

3.0

Pip5k1b

Phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1-beta) (PtdIns(4)P-5-kinase 1 beta) (EC 2.7.1.68) (Phosphatidylinositol
4-phosphate 5-kinase type I alpha) (PIP5KIalpha) (Phosphatidylinositol 4-phosphate 5-kinase type I beta) (PIP5KIbeta)

Rattus norvegicus
TI:10116 None

A0A1D5PV96_CHICK
Ensembl»

1.5

PIP4K2B

Phosphatidylinositol-5-phosphate 4-kinase
type 2 beta

Gallus gallus
TI:9031 None

M0RBR8_RAT
RGD»

3.0

Pip5kl1

Phosphatidylinositol-4-phosphate 5-kinase-like 1

Rattus norvegicus
TI:10116 None

ITS3_SCHPO
PomBase»

7.4

its3

Phosphatidylinositol 4-phosphate 5-kinase its3 (EC 2.7.1.68)
(1-phosphatidylinositol 4-phosphate kinase) (Diphosphoinositide kinase) (PIP5K) (PtdIns(4)P-5-kinase)

Schizosaccharomyces pombe
TI:4896 None

Q8SXX1_DROME
FlyBase»

8.7

PIP4K

Phosphatidylinositol 5-phosphate 4-kinase, isoform A (Phosphatidylinositol
5-phosphate 4-kinase, isoform B (EC 2.7.1.149)) (RH07911p)

Drosophila melanogaster
TI:7227 None

PI42A_CHICK
CTD»

4.5

PIP4K2A

Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha)
(Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(5)P-4-kinase isoform 2-alpha)

Gallus gallus
TI:9031 None

PI42C_MOUSE
Ensembl»

1.5

Pip4k2c

Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate
4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)

Mus musculus
TI:10090 None

PI42C_RAT
RGD»

6.9

Pip4k2c

Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate
4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)

Rattus norvegicus
TI:10116 None

Q86D86_DICDI
dictyBase»

9.0

rpkA

G-protein-coupled receptor family protein (RpkA)

Dictyostelium discoideum
TI:44689 None

PI51B_HUMAN
Ensembl»

7.5

PIP5K1B

Phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1-beta) (PtdIns(4)P-5-kinase 1 beta) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate
5-kinase type I beta) (PIP5KIbeta) (Protein STM-7) (Type I phosphatidylinositol 4-phosphate 5-kinase beta)

Homo sapiens
TI:9606 None

PI42C_HUMAN
Ensembl»

6.3

PIP4K2C

Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate
4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma)

Homo sapiens
TI:9606 None

Q9W2R3_DROME
FlyBase»

7.4

sktl

LP03320p (Skittles, isoform A (EC 2.7.1.68))
(Skittles, isoform B) (Skittles, isoform C)

Drosophila melanogaster
TI:7227 None

PI42B_MOUSE
Ensembl»

5.4

Pip4k2b

Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta)
(Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta)

Mus musculus
TI:10090 None

PI42A_MOUSE
Ensembl»

4.9

Pip4k2a

Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (Phosphatidylinositol 5-Phosphate
4-Kinase) (PI5P4Kalpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(5)P-4-kinase isoform 2-alpha)

Mus musculus
TI:10090 None

PI42B_HUMAN
Ensembl»

9.8

PIP4K2B

Homo sapiens
TI:9606 None

PI51A_RAT
RGD»

7.0

Pip5k1a

Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68
kDa type I phosphatidylinositol 4-phosphate 5-kinase) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)

Rattus norvegicus
TI:10116 None

PI42B_RAT
RGD»

10.0

Pip4k2b

Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate
4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (Phosphatidylinositol-phosphate kinase IIgamma) (PIPKIIgamma) (PtdIns(5)P-4-kinase isoform 2-beta)

Rattus norvegicus
TI:10116 None

PI42A_HUMAN
Ensembl»

9.5

PIP4K2A

Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (PIP5KIII) (Phosphatidylinositol 5-Phosphate 4-Kinase) (PI5P4Kalpha) (Phosphatidylinositol
5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(4)P-5-kinase B isoform) (PtdIns(4)P-5-kinase C isoform) (PtdIns(5)P-4-kinase isoform 2-alpha)

Homo sapiens
TI:9606 None

PI51C_RAT
RGD»

5.0

Pip5k1c

Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma)
(EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma)

Rattus norvegicus
TI:10116 None

PI51C_MOUSE
Ensembl»

10.4

Pip5k1c

Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma)
(EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma)

Mus musculus
TI:10090 None

PI51A_MOUSE
Ensembl»

7.8

Pip5k1a

Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa type I phosphatidylinositol
4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha) (Phosphatidylinositol 4-phosphate 5-kinase type I beta) (PI4P5KIbeta)

Mus musculus
TI:10090 None

PI51C_HUMAN
Ensembl»

12.7

PIP5K1C

Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1gamma) (PtdIns(4)P-5-kinase 1
gamma) (EC 2.7.1.68) (Type I phosphatidylinositol 4-phosphate 5-kinase gamma)

Homo sapiens
TI:9606 None

PI42A_RAT
RGD»

10.0

Pip4k2a

Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (PIPK2
alpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4KII-alpha) (PtdIns(5)P-4-kinase isoform 2-alpha)

Rattus norvegicus
TI:10116 None

PI51A_HUMAN
Ensembl»

17.8

PIP5K1A

Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1-alpha) (PtdIns(4)P-5-kinase 1 alpha) (EC 2.7.1.68) (68 kDa
type I phosphatidylinositol 4-phosphate 5-kinase alpha) (Phosphatidylinositol 4-phosphate 5-kinase type I alpha) (PIP5KIalpha)

Homo sapiens
TI:9606 None

Cluster UKP01333

Collated Gene Ontology terms

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Proteins