Cluster UKP01050
- TETRATRICOPEPTIDE-LIKE HELICAL
Standard knownness: 6.0; Custom knownness: None; Num. species: 86; Orthology database: Panther19.0; Protein members: 100
Collated Gene Ontology terms
Biological process:
protein serine/threonine kinase activity(2024, 2025)
transferase activity(2025)
protein kinase activity(2025)
nucleotide binding(2025)
kinase activity(2025)
ATP binding(2025)
Molecular function:
regulatory ncRNA-mediated heterochromatin formation2015, 2024, 2025
negative regulation of RNA catabolic process2023, 2025
RNA processing2025
mRNA stabilization2022, 2025
RNA splicing2020, 2025
DNA damage response2020, 2025
positive regulation of RNA export from nucleus2019, 2025
mitotic cell cycle2020, 2025
mRNA processing2025
cell division2025
regulatory ncRNA-mediated gene silencing2012, 2025
siRNA-mediated facultative heterochromatin formation2014
regulatory ncRNA-mediated post-transcriptional gene silencing2011
nuclear mRNA surveillance of spliceosomal pre-mRNA splicing2023
mRNA splicing, via spliceosome2010
Cellular component: nucleus2009, 2012, 2018, 2020, 2025 nuclear speck2019, 2020, 2025 nucleolus2019, 2025 nucleoplasm2019, 2025 mitochondrion2024, 2025 catalytic step 2 spliceosome2010, 2025 spliceosomal complex2021 membrane2025
Phylogenetic distribution
| Chordates: | 22/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 12/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 0/4 | |
| Harosa: | 1/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 37/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Q9LSH4_ARATH TAIR» |
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At3g17740 At3g17740/MIG5_3 | At3g17740 |
Arabidopsis thaliana TI:3702 None |
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A0A7U2ES19_PHANO TubercuList» |
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JI435_022040 | DUF1740-domain-containing protein |
Phaeosphaeria nodorum TI:13684 None |
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A7F4M7_SCLS1 TubercuList» |
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SS1G_12552 | DUF1740-domain-containing protein |
Sclerotinia sclerotiorum TI:5180 None |
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E3KBE5_PUCGT TubercuList» |
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PGTG_07907 | DUF1740-domain-containing protein |
Puccinia graminis TI:5297 None |
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Q5B1X4_EMENI TubercuList» |
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ANIA_05456 | DUF1740-domain-containing protein |
Emericella nidulans TI:162425 None |
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Q5K7T3_CRYD1 TubercuList» |
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CNM01360 | DUF1740-domain-containing protein |
Cryptococcus deneoformans TI:40410 None |
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Q7RYK9_NEUCR TubercuList» |
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NCU00120 | DUF1740-domain-containing protein |
Neurospora crassa TI:5141 None |
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B6K0D8_SCHJY TubercuList» |
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nrl1 | DuF1740 family protein |
Schizosaccharomyces japonicus TI:4897 None |
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Q6IRN3_XENLA Xenbase» |
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nrde2.L | MGC83828 protein (NRDE-2, necessary for RNA interference, domain containing L homeolog) |
Xenopus laevis TI:8355 None |
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A0A6I8PAN7_ORNAN Ensembl» |
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NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
Ornithorhynchus anatinus TI:9258 None |
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A0A8V0Z1Z2_CHICK Ensembl» |
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NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
Gallus gallus TI:9031 None |
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A0ABI7X9K7_FELCA Ensembl» |
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NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
Felis catus TI:9685 None |
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D3ZDR9_RAT RGD» |
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Nrde2 | NRDE-2, necessary for RNA interference, domain containing |
Rattus norvegicus TI:10116 None |
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F7CXT9_MONDO Ensembl» |
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NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
Monodelphis domestica TI:13616 None |
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G1KQ07_ANOCA Ensembl» |
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NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
Anolis carolinensis TI:28377 None |
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H2MTT5_ORYLA Ensembl» |
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NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
Oryzias latipes TI:8090 None |
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Q4WLJ0_ASPFU TubercuList» |
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AFUA_6G13360 | NRDE-2, necessary for RNA interference-domain-containing protein |
Aspergillus fumigatus TI:746128 None |
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W5MRK8_LEPOC Ensembl» |
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NRDE-2, necessary for RNA interference, domain containing |
Lepisosteus oculatus TI:7918 None |
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A0A6I8PV13_XENTR Xenbase» |
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nrde2 | NRDE-2, necessary for RNA interference, domain containing (Nuclear exosome regulator NRDE2 isoform X1) |
Xenopus tropicalis TI:8364 None |
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A0A3Q1NNB2_BOVIN Ensembl» |
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NRDE2 | Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) |
Bos taurus TI:9913 None |
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A0A8I3NQK7_CANLF Ensembl» |
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NRDE2 | Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) |
Canis lupus TI:9612 None |
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A0A9L0SGG4_HORSE Ensembl» |
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NRDE2 | Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) |
Equus caballus TI:9796 None |
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F1SDA5_PIG Ensembl» |
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NRDE2 | Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) |
Sus scrofa TI:9823 None |
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F7CR99_MACMU Ensembl» |
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NRDE2 | Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) |
Macaca mulatta TI:9544 None |
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G3R0F7_GORGO Ensembl» |
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NRDE2 | Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) |
Gorilla gorilla TI:9593 None |
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H2R982_PANTR Ensembl» |
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NRDE2 | Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) |
Pan troglodytes TI:9598 None |
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NRDE2_DICDI dictyBase» |
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nrde2 | Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) |
Dictyostelium discoideum TI:44689 None |
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NRDE2_HUMAN Ensembl» |
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NRDE2 | Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) |
Homo sapiens TI:9606 None |
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NRDE2_MOUSE Ensembl» |
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Nrde2 | Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) |
Mus musculus TI:10090 None |
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A0A2I4GZ24_JUGRE euHCVdb» |
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LOC109012102 | Nuclear exosome regulator NRDE2 |
Juglans regia TI:51240 None |
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A0ACD6B5I2_DANRE ZFIN» |
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nrde2 | Nuclear exosome regulator NRDE2 |
Danio rerio TI:7955 None |
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NRDE2_CAEEL WormBase» |
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nrde-2 | Nuclear exosome regulator NRDE2 (Nuclear RNAi defective-2 protein) |
Caenorhabditis elegans TI:6239 None |
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A0A1U8JS35_GOSHI euHCVdb» |
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LOC107908438 | Nuclear exosome regulator NRDE2 isoform X1 |
Gossypium hirsutum TI:3635 None |
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A0ABM3ABZ7_GOSHI neXtProt» |
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LOC107887131 | Nuclear exosome regulator NRDE2 isoform X1 |
Gossypium hirsutum TI:3635 None |
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A0A6P9EQM4_JUGRE euHCVdb» |
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LOC118348493 | Nuclear exosome regulator NRDE2-like |
Juglans regia TI:51240 None |
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A0A9J7LVD7_BRAFL euHCVdb» |
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LOC118425103 | Nuclear exosome regulator NRDE2-like |
Branchiostoma floridae TI:7739 None |
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Q6ZHF3_ORYSJ euHCVdb» |
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Os02g0772500 | Os02g0772500 protein |
Oryza sativa TI:4530 None |
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F2DY98_HORVV EnsemblPlants» |
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LOC123404721 | Predicted protein |
Hordeum vulgare TI:4513 None |
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H8WH80_CAEBR WormBase» |
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nrde-2 | Protein CBR-NRDE-2 |
Caenorhabditis briggsae TI:6238 None |
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A0A804PNU6_MAIZE EnsemblPlants» |
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LOC100274011 | Protein NRDE2 |
Zea mays TI:4577 None |
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A0A022Q2P1_ERYGU euHCVdb» |
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MIMGU_mgv1a000564mg | Protein NRDE2 homolog |
Erythranthe guttata TI:4155 None |
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A0A067DUY2_CITSI neXtProt» |
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CISIN_1g001167mg | Protein NRDE2 homolog |
Citrus sinensis TI:2711 None |
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A0A0A0LVY4_CUCSA euHCVdb» |
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Csa_1G043050 | Protein NRDE2 homolog |
Cucumis sativus TI:3659 None |
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A0A0K9PN27_ZOSMR euHCVdb» |
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ZOSMA_20G00900 | Protein NRDE2 homolog |
Zostera marina TI:29655 None |
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A0A1S3ZHR1_TOBAC euHCVdb» |
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LOC107786802 | Protein NRDE2 homolog (Uncharacterized protein LOC107786802) |
Nicotiana tabacum TI:4097 None |
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A0A1S4H4P1_ANOGA EnsemblMetazoa» |
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Protein NRDE2 homolog |
Anopheles gambiae TI:7165 None |
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A0A1U8B5Q7_NELNU neXtProt» |
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LOC104611077 | Protein NRDE2 homolog |
Nelumbo nucifera TI:4432 None |
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A0A2C9VLL0_MANES euHCVdb» |
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MANES_06G000900v8 | Protein NRDE2 homolog |
Manihot esculenta TI:3983 None |
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A0A2G3A0U8_CAPAN euHCVdb» |
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T459_09927 | Protein NRDE2 homolog |
Capsicum annuum TI:4072 None |
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A0A3B6NV53_WHEAT EnsemblPlants» |
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LOC123128516 | Protein NRDE2 homolog |
Triticum aestivum TI:4565 None |
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A0A3B6PSJ8_WHEAT EnsemblPlants» |
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LOC123145640 | Protein NRDE2 homolog |
Triticum aestivum TI:4565 None |
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A0A3B6QLR8_WHEAT EnsemblPlants» |
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Protein NRDE2 homolog |
Triticum aestivum TI:4565 None |
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A0A7M7PUR5_STRPU EnsemblMetazoa» |
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Protein NRDE2 homolog |
Strongylocentrotus purpuratus TI:7668 None |
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A0A804KRA5_MUSAM EnsemblPlants» |
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Protein NRDE2 homolog |
Musa acuminata TI:4641 None |
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A0A9R0J890_SPIOL euHCVdb» |
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LOC110800734 | Protein NRDE2 homolog |
Spinacia oleracea TI:3562 None |
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A7RZP5_NEMVE neXtProt» |
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NEMVEDRAFT_v1g241809 | Protein NRDE2 homolog |
Nematostella vectensis TI:45351 None |
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B9SNW2_RICCO neXtProt» |
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RCOM_0582330 | Protein NRDE2 homolog |
Ricinus communis TI:3988 None |
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C5XTI0_SORBI euHCVdb» |
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SORBI_3004G314000 | Protein NRDE2 homolog |
Sorghum bicolor TI:4558 None |
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F4J6D7_ARATH TAIR» |
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At3g17712 | Protein NRDE2 homolog |
Arabidopsis thaliana TI:3702 None |
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F6QKB5_CIOIN Ensembl» |
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LOC100177099 | Protein NRDE2 homolog |
Ciona intestinalis TI:7719 None |
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NRDE2_SCHPO PomBase» |
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SPBC20F10.05 | Protein NRDE2 homolog |
Schizosaccharomyces pombe TI:4896 None |
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D6W9C7_TRICA euHCVdb» |
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AUGUSTUS-3.0.2_00974 | Protein NRDE2 homolog-like Protein |
Tribolium castaneum TI:7070 None |
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F6HW74_VITVI neXtProt» |
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VIT_17s0119g00310 | Protein NRDE2-like |
Vitis vinifera TI:29760 None |
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F6HW75_VITVI neXtProt» |
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VIT_17s0119g00330 | Protein NRDE2-like |
Vitis vinifera TI:29760 None |
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W1PM14_AMBTC neXtProt» |
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AMTR_s00024p00121650 | Protein kinase domain-containing protein |
Amborella trichopoda TI:13333 None |
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G7JP36_MEDTR EnsemblPlants» |
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11415298 | Putative siRNA-mediated silencing protein NRDE-2 |
Medicago truncatula TI:3880 None |
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A0A251VKK6_HELAN euHCVdb» |
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HannXRQ_Chr01g0002621 HanXRQr2_Chr14g0625691 | SiRNA-mediated silencing protein NRDE-2 |
Helianthus annuus TI:4232 None |
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A0A2K1XHD6_POPTR euHCVdb» |
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POPTR_015G033300 | Suppressor of forked domain-containing protein |
Populus trichocarpa TI:3694 None |
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A0A2R6W2R1_MARPO euHCVdb» |
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MARPO_0172s0015 | Suppressor of forked domain-containing protein |
Marchantia polymorpha TI:3197 None |
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A0A3Q7FN71_SOLLC EnsemblPlants» |
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LOC101265113 | Suppressor of forked domain-containing protein |
Solanum lycopersicum TI:4081 None |
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A0A7I4EHU7_PHYPA EnsemblPlants» |
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LOC112286922 | Suppressor of forked domain-containing protein |
Physcomitrium patens TI:3218 None |
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B3S6G4_TRIAD CTD» |
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TRIADDRAFT_30197 | Suppressor of forked domain-containing protein |
Trichoplax adhaerens TI:10228 None |
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D8R9W7_SELML neXtProt» |
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SELMODRAFT_88336 | Suppressor of forked domain-containing protein |
Selaginella moellendorffii TI:88036 None |
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D8SEJ0_SELML euHCVdb» |
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SELMODRAFT_179031 | Suppressor of forked domain-containing protein |
Selaginella moellendorffii TI:88036 None |
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F0ZZ12_DICPU TubercuList» |
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DICPUDRAFT_99413 | Suppressor of forked domain-containing protein |
Dictyostelium purpureum TI:5786 None |
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I1L3Z9_SOYBN EnsemblPlants» |
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LOC100812285 | Suppressor of forked domain-containing protein |
Glycine max TI:3847 None |
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I1MQN2_SOYBN EnsemblPlants» |
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LOC100786596 | Suppressor of forked domain-containing protein |
Glycine max TI:3847 None |
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M4E0E1_BRACM EnsemblPlants» |
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Suppressor of forked domain-containing protein |
Brassica campestris TI:3711 None |
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A0A061FXE1_THECC euHCVdb» |
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TCM_013315 | UPF0614 protein C14orf102, putative isoform 1 |
Theobroma cacao TI:3641 None |
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A0A1Y1HKF9_KLENI neXtProt» |
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KFL_000240040 | Uncharacterized protein |
Klebsormidium nitens TI:105231 None |
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A0A251PD18_PRUPE euHCVdb» |
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PRUPE_5G239800 | Uncharacterized protein |
Prunus persica TI:3760 None |
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A0A2A6B923_PRIPA EnsemblMetazoa» |
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WBGene00098731 | Uncharacterized protein |
Pristionchus pacificus TI:54126 None |
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A0A2G2ZN18_CAPAN euHCVdb» |
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T459_11784 | Uncharacterized protein |
Capsicum annuum TI:4072 None |
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A0A2K3D0Z2_CHLRE euHCVdb» |
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CHLRE_13g589650v5 | Uncharacterized protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A9R1UGY2_LACSA euHCVdb» |
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LSAT_V11C900460170 | Uncharacterized protein |
Lactuca sativa TI:4236 None |
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A0A9R1WVW6_LACSA euHCVdb» |
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LSAT_V11C900460190 | Uncharacterized protein |
Lactuca sativa TI:4236 None |
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A0A9R1XSB3_LACSA neXtProt» |
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LSAT_V11C200056200 | Uncharacterized protein |
Lactuca sativa TI:4236 None |
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A0DU55_PARTE neXtProt» |
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GSPATT00020243001 | Uncharacterized protein |
Paramecium tetraurelia TI:5888 None |
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A9UTC3_MONBE neXtProt» |
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MONBRDRAFT_23417 | Uncharacterized protein |
Monosiga brevicollis TI:81824 None |
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B7P6Q4_IXOSC EnsemblMetazoa» |
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IscW_ISCW001175 | Uncharacterized protein |
Ixodes scapularis TI:6945 None |
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E9H5W0_DAPPU neXtProt» |
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DAPPUDRAFT_308050 | Uncharacterized protein |
Daphnia pulex TI:6669 None |
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F4P9P8_BATDJ neXtProt» |
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BATDEDRAFT_91264 | Uncharacterized protein |
Batrachochytrium dendrobatidis TI:109871 None |
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G7KIG9_MEDTR EnsemblPlants» |
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MTR_6g072640 | Uncharacterized protein |
Medicago truncatula TI:3880 None |
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G7KJ52_MEDTR EnsemblPlants» |
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MTR_6g074610 | Uncharacterized protein |
Medicago truncatula TI:3880 None |
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I1IEQ2_BRADI EnsemblPlants» |
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LOC100822966 | Uncharacterized protein |
Brachypodium distachyon TI:15368 None |
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K3YPF1_SETIT EnsemblPlants» |
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LOC101761529 | Uncharacterized protein |
Setaria italica TI:4555 None |
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T1FVA9_HELRO EnsemblMetazoa» |
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20212755 | Uncharacterized protein |
Helobdella robusta TI:6412 None |
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A0A1S3ZC07_TOBAC neXtProt» |
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LOC107785207 | Uncharacterized protein LOC107785207 isoform X1 |
Nicotiana tabacum TI:4097 None |
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Q9VXW9_DROME FlyBase» |
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Dmel\CG5877 | Uncharacterized protein, isoform A (Uncharacterized protein, isoform D) |
Drosophila melanogaster TI:7227 None |
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Q6C750_YARLI TubercuList» |
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YALI0_E03762g | YALI0E03762p |
Yarrowia lipolytica TI:4952 None |
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