Collated Gene Ontology terms

Biological process: protein serine/threonine kinase activity(2024, 2025) transferase activity(2025) protein kinase activity(2025) nucleotide binding(2025) kinase activity(2025) ATP binding(2025)

Molecular function: regulatory ncRNA-mediated heterochromatin formation2015, 2024, 2025 negative regulation of RNA catabolic process2023, 2025 RNA processing2025 mRNA stabilization2022, 2025 RNA splicing2020, 2025 DNA damage response2020, 2025 positive regulation of RNA export from nucleus2019, 2025 mitotic cell cycle2020, 2025 mRNA processing2025 cell division2025
regulatory ncRNA-mediated gene silencing2012, 2025 siRNA-mediated facultative heterochromatin formation2014 regulatory ncRNA-mediated post-transcriptional gene silencing2011 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing2023 mRNA splicing, via spliceosome2010

Cellular component: nucleus2009, 2012, 2018, 2020, 2025 nuclear speck2019, 2020, 2025 nucleolus2019, 2025 nucleoplasm2019, 2025 mitochondrion2024, 2025 catalytic step 2 spliceosome2010, 2025 spliceosomal complex2021 membrane2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 12/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q9LSH4_ARATH
TAIR»
1.0
At3g17740 At3g17740/MIG5_3 At3g17740 Arabidopsis thaliana
TI:3702 None
 
A0A8V0Z1Z2_CHICK
Ensembl»
1.0
NRDE2 NRDE-2, necessary for
RNA interference, domain containing		 Gallus gallus
TI:9031 None
   
D3ZDR9_RAT
RGD»
2.5
Nrde2 NRDE-2, necessary for
RNA interference, domain containing		 Rattus norvegicus
TI:10116 None
   
NRDE2_DICDI
dictyBase»
1.5
nrde2 Nuclear exosome regulator
NRDE2 (Protein NRDE2 homolog)		 Dictyostelium discoideum
TI:44689 None
 
NRDE2_HUMAN
Ensembl»
5.0
NRDE2 Nuclear exosome regulator
NRDE2 (Protein NRDE2 homolog)		 Homo sapiens
TI:9606 None
 
NRDE2_MOUSE
Ensembl»
6.0
Nrde2 Nuclear exosome regulator
NRDE2 (Protein NRDE2 homolog)		 Mus musculus
TI:10090 None
 
A0ACD6B5I2_DANRE
ZFIN»
0.0
nrde2 Nuclear exosome regulator NRDE2 Danio rerio
TI:7955 None 		     
NRDE2_CAEEL
WormBase»
3.9
nrde-2 Nuclear exosome regulator NRDE2
(Nuclear RNAi defective-2 protein)		 Caenorhabditis elegans
TI:6239 None
 
F4J6D7_ARATH
TAIR»
1.0
At3g17712 Protein NRDE2 homolog Arabidopsis thaliana
TI:3702 None
 
NRDE2_SCHPO
PomBase»
2.6
SPBC20F10.05 Protein NRDE2 homolog Schizosaccharomyces pombe
TI:4896 None
 
Q9VXW9_DROME
FlyBase»
2.0
Dmel\CG5877 Uncharacterized protein, isoform A
(Uncharacterized protein, isoform D)		 Drosophila melanogaster
TI:7227 None