Collated Gene Ontology terms

Biological process: catalytic activity(2024) isomerase activity(2024) oxaloacetate tautomerase activity(2024) hydrolase activity(2024) metal ion binding(2024) lyase activity(2024) acetylpyruvate hydrolase activity(2019, 2021) 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity(2024) magnesium ion binding(2014) hydro-lyase activity(2014)

Molecular function: oxaloacetate metabolic process2024 protein homotetramerization2014 D-arabinose catabolic process2014

Cellular component: mitochondrion2009, 2024

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 6/8 
Bacteria: 8/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
FAH2A_HUMAN
Ensembl»
1.6
FAHD2A Fumarylacetoacetate hydrolase domain-containing
protein 2A (EC 3.-.-.-)		 Homo sapiens
TI:9606 None
 
FAH2B_HUMAN
Ensembl»
1.6
FAHD2B Fumarylacetoacetate hydrolase domain-containing
protein 2B (EC 3.-.-.-)		 Homo sapiens
TI:9606 None
 
FAHD2_BOVIN
CTD»
0.0
FAHD2 Fumarylacetoacetate hydrolase domain-containing
protein 2 (EC 3.-.-.-)		 Bos taurus
TI:9913 None
 
FAHD2_MOUSE
AG»
1.0
Fahd2 Fumarylacetoacetate hydrolase domain-containing
protein 2A (EC 3.-.-.-)		 Mus musculus
TI:10090 None
 
F1MLX0_BOVIN
Ensembl»
0.0
FAHD2A Fumarylacetoacetate hydrolase
domain containing 2A		 Bos taurus
TI:9913 None
   
FAHD2_RAT
RGD»
1.0
Fahd2 Fumarylacetoacetate hydrolase domain-containing
protein 2 (EC 3.-.-.-)		 Rattus norvegicus
TI:10116 None
 
FAHD2_XENLA
Xenbase»
0.0
fahd2 Oxaloacetate tautomerase fahd2, mitochondrial (EC
5.3.2.2) (Fumarylacetoacetate hydrolase domain-containing protein 2)		 Xenopus laevis
TI:8355 None
 
KDAD_SACS2
EnsemblBacteria»
0.0
kdaD 2-dehydro-3-deoxy-D-arabinonate dehydratase (EC
4.2.1.141) (2-keto-3-deoxy-D-arabinonate dehydratase) (KdaD)		 Saccharolobus solfataricus
TI:2287 None
 
B8E1S5_DICTD
EnsemblBacteria»
0.0
Dtur_0404 5-carboxymethyl-2-hydroxymuconate Delta-isomerase
(EC 5.3.3.10)		 Dictyoglomus turgidum
TI:513050 None
 
H2QIC3_PANTR
Ensembl»
0.0
FAHD2A Fumarylacetoacetate hydrolase domain containing 2A
(Fumarylacetoacetate hydrolase domain containing 2B)		 Pan troglodytes
TI:9598 None
 
Q95SI7_DROME
FlyBase»
1.0
Dmel\CG6028 GH23390p Drosophila melanogaster
TI:7227 None
 
Q9VU50_DROME
FlyBase»
0.5
Dmel\CG11251 IP10719p Drosophila melanogaster
TI:7227 None
 
A0A0H2W4Z6_YERPE
EnsemblBacteria»
0.0
YPO1566 FAA hydrolase family
protein (Hydrolase (EC 5.3.3.-))		 Yersinia pestis
TI:632 None
 
A0A5F5PJB5_HORSE
Ensembl»
0.0
FAHD2A Fumarylacetoacetate hydrolase
domain containing 2A		 Equus caballus
TI:9796 None
   
A0A8I3N070_CANLF
Ensembl»
0.0
FAHD2A Fumarylacetoacetate hydrolase
domain containing 2A		 Canis lupus
TI:9612 None
   
A9A422_NITMS
EnsemblBacteria»
0.0
Nmar_0310 5-carboxymethyl-2-hydroxymuconate Delta-isomerase
(EC 5.3.3.10)		 Nitrosopumilus maritimus
TI:338192 None
 
B1L3C0_KORCO
EnsemblBacteria»
0.0
Kcr_0189 5-carboxymethyl-2-hydroxymuconate Delta-isomerase
(EC 5.3.3.10)		 Korarchaeum cryptofilum
TI:498846 None
 
F6VG73_ORNAN
Ensembl»
0.0
FAHD2A Fumarylacetoacetate hydrolase
domain containing 2A		 Ornithorhynchus anatinus
TI:9258 None
   
F7CKR3_MONDO
Ensembl»
0.0
FAHD2A Fumarylacetoacetate hydrolase
domain containing 2A		 Monodelphis domestica
TI:13616 None
   
FAHD2_DICDI
dictyBase»
0.0
fahd2 Fumarylacetoacetate hydrolase domain-containing protein
2 homolog (EC 3.-.-.-)		 Dictyostelium discoideum
TI:44689 None
 
Q7UKL0_RHOBA
EnsemblBacteria»
0.0
RB10092 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase
(EC 4.1.1.-, EC 5.3.3.-)		 Rhodopirellula baltica
TI:265606 None
 
Q7UMG2_RHOBA
EnsemblBacteria»
0.0
hpaG Probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomaerase
(EC 4.1.1.-, EC 5.3.3.-)		 Rhodopirellula baltica
TI:265606 None
 
Q89PR7_BRADU
EnsemblBacteria»
0.0
blr3413 Blr3413 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q8TT54_METAC
EnsemblBacteria»
0.0
hpcE 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase Methanosarcina acetivorans
TI:2214 None
 
A0A1L8H1M1_XENLA
Xenbase»
0.0
fahd2a.L Fumarylacetoacetate hydrolase domain-containing
protein 2 isoform X1		 Xenopus laevis
TI:8355 None
   
A0A8M9QDP1_DANRE
CTD»
0.0
fahd2a Fumarylacetoacetate hydrolase domain-containing
protein 2A isoform X1		 Danio rerio
TI:7955 None
   
A0A9J7MPU9_BRAFL
CTD»
0.0
LOC118414648 Fumarylacetoacetate hydrolase
domain-containing protein 2-like		 Branchiostoma floridae
TI:7739 None
   
D6WZV5_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_12729 Fumarylacetoacetate hydrolase domain-containing
protein 2A-like Protein		 Tribolium castaneum
TI:7070 None
 
D6WZV6_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_12730 Fumarylacetoacetate hydrolase domain-containing
protein 2A-like Protein		 Tribolium castaneum
TI:7070 None
 
F6QF40_XENTR
Xenbase»
0.0
fahd2a Fumarylacetoacetate hydrolase domain containing 2A (Fumarylacetoacetate
hydrolase domain-containing protein 2A isoform X1)		 Xenopus tropicalis
TI:8364 None
   
H9FV51_MACMU
Ensembl»
0.0
FAHD2A Fumarylacetoacetate hydrolase
domain-containing protein 2A		 Macaca mulatta
TI:9544 None
 
Q89CA6_BRADU
EnsemblBacteria»
0.0
blr7891 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q8F774_LEPIN
EnsemblBacteria»
0.0
mhpD Fumarylacetoacetate hydrolase family protein Leptospira interrogans
TI:173 None
 
Q8ZRI8_SALTY
EnsemblBacteria»
0.0
STM0331 Fumarylacetoacetate (FAA) hydrolase Salmonella typhimurium
TI:28901 None
 
Q8ZUN9_PYRAE
EnsemblBacteria»
0.0
PAE2688 2-hydroxyhepta-2,4-diene-1,7-dioate
isomerase, conjectural		 Pyrobaculum aerophilum
TI:13773 None
 
Q93RT3_STRCO
EnsemblBacteria»
0.0
SCO6308 Hydrolase Streptomyces coelicolor
TI:1902 None
 
Q97UR1_SACS2
EnsemblBacteria»
0.0
hpcE-3 2-hydroxyhepta-2, 4-diene-1,7-dioate
isomerase (HpcE-3)		 Saccharolobus solfataricus
TI:2287 None
 
Q97V63_SACS2
EnsemblBacteria»
0.0
hpcE-2 2-hydroxyhepta-2,4-diene-1,7-dioate
isomerase (HpcE-2)		 Saccharolobus solfataricus
TI:2287 None
 
Q9RDA1_STRCO
EnsemblBacteria»
0.0
SCO2850 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase Streptomyces coelicolor
TI:1902 None
 
Q9RJW4_STRCO
EnsemblBacteria»
0.0
SCO0346 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase Streptomyces coelicolor
TI:1902 None
 
Y1656_METJA
EnsemblBacteria»
0.0
MJ1656 Uncharacterized protein MJ1656 Methanocaldococcus jannaschii
TI:2190 None
 
A0A287ACG3_PIG
Ensembl»
0.0
Fumarylacetoacetase-like C-terminal
domain-containing protein		 Sus scrofa
TI:9823 None
   
A0A2I2UKU1_FELCA
Ensembl»
0.0
FAHD2A Fumarylacetoacetate hydrolase
domain containing 2A		 Felis catus
TI:9685 None
 
A0A2I2Y9P1_GORGO
Ensembl»
0.0
Fumarylacetoacetase-like C-terminal
domain-containing protein		 Gorilla gorilla
TI:9593 None
 
A0A2I3SN57_PANTR
Ensembl»
0.0
Fumarylacetoacetase-like C-terminal
domain-containing protein		 Pan troglodytes
TI:9598 None
 
A0A2I3T937_PANTR
Ensembl»
0.0
FAHD2B Fumarylacetoacetase-like C-terminal
domain-containing protein		 Pan troglodytes
TI:9598 None
   
A0A2I3TPA2_PANTR
Ensembl»
0.0
Fumarylacetoacetase-like C-terminal
domain-containing protein		 Pan troglodytes
TI:9598 None
 
A0A2S9PIA6_YERPE
EnsemblBacteria»
0.0
YPO1289 Fumarylacetoacetate hydrolase Yersinia pestis
TI:632 None
 
A0A3B3HCX8_ORYLA
Ensembl»
0.0
FAHD2A Fumarylacetoacetate hydrolase
domain-containing protein 2		 Oryzias latipes
TI:8090 None
   
A0A5G2R332_PIG
Ensembl»
0.0
Fumarylacetoacetase-like C-terminal
domain-containing protein		 Sus scrofa
TI:9823 None
   
A0A7M7G1J1_STRPU
EnsemblMetazoa»
0.0
Fumarylacetoacetase-like C-terminal
domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A8V0ZJJ0_CHICK
Ensembl»
0.0
FAHD2A Fumarylacetoacetate hydrolase
domain containing 2A		 Gallus gallus
TI:9031 None
   
A7SGM7_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g245160 Fumarylacetoacetase-like C-terminal
domain-containing protein		 Nematostella vectensis
TI:45351 None
 
A9UWE4_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_18582 Fumarylacetoacetase-like C-terminal
domain-containing protein		 Monosiga brevicollis
TI:81824 None
 
B8BUB3_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_31737 Fumarylacetoacetase-like C-terminal
domain-containing protein		 Thalassiosira pseudonana
TI:35128 None
 
E9HJQ5_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_330490 Fumarylacetoacetase-like C-terminal
domain-containing protein		 Daphnia pulex
TI:6669 None
 
E9HJQ6_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_260718 Fumarylacetoacetase-like C-terminal
domain-containing protein		 Daphnia pulex
TI:6669 None
 
E9HJQ7_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_218409 Fumarylacetoacetase-like C-terminal
domain-containing protein		 Daphnia pulex
TI:6669 None
 
F0ZG82_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_46773 Fumarylacetoacetase-like C-terminal
domain-containing protein		 Dictyostelium purpureum
TI:5786 None
 
F6W2L5_CIOIN
Ensembl»
0.0
LOC100181820 Fumarylacetoacetate hydrolase
domain-containing protein 2		 Ciona intestinalis
TI:7719 None
 
G3RJF7_GORGO
Ensembl»
0.0
Fumarylacetoacetase-like C-terminal
domain-containing protein		 Gorilla gorilla
TI:9593 None
 
G3RWB7_GORGO
Ensembl»
0.0
Fumarylacetoacetase-like C-terminal
domain-containing protein		 Gorilla gorilla
TI:9593 None
 
Q5TMH4_ANOGA
EnsemblMetazoa»
0.0
1280998 AGAP011634-PA Anopheles gambiae
TI:7165 None
 
Q89D60_BRADU
EnsemblBacteria»
0.0
blr7583 Blr7583 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q89GI5_BRADU
EnsemblBacteria»
0.0
bll6360 Bll6360 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q89JJ8_BRADU
EnsemblBacteria»
0.0
blr5285 Blr5285 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q89QC9_BRADU
EnsemblBacteria»
0.0
blr3199 Blr3199 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q89R06_BRADU
EnsemblBacteria»
0.0
bll2966 Bll2966 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q89V19_BRADU
EnsemblBacteria»
0.0
blr1239 Blr1239 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q8P3K3_XANCP
EnsemblBacteria»
0.0
XCC4068 2-hydroxyhepta-2,4-diene-1,
7-dioateisomerase/5-carboxymethyl-2-oxo-hex-3-ene-1, 7-dioatedecarboxylase		 Xanthomonas campestris
TI:339 None
 
Q9RJU9_STRCO
EnsemblBacteria»
0.0
SCO0361 Fumarylacetoacetase-like C-terminal
domain-containing protein		 Streptomyces coelicolor
TI:1902 None
 
W5NF46_LEPOC
Ensembl»
0.0
FAHD2B Fumarylacetoacetate hydrolase
domain containing 2B		 Lepisosteus oculatus
TI:7918 None