Collated Gene Ontology terms

Biological process: oxidoreductase activity(2014, 2024) estradiol 17-beta-dehydrogenase [NAD(P)] activity(2017, 2018, 2024) 3-keto sterol reductase activity(2017, 2018, 2024) 17-beta-ketosteroid reductase activity(2017, 2018, 2024) 17-beta-hydroxysteroid dehydrogenase (NADP+) activity(2017, 2018, 2024) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(2023, 2024) nucleotide binding(2024) NAD-retinol dehydrogenase activity(2014, 2024)

Molecular function: steroid biosynthetic process2017, 2024 steroid metabolic process2024 estrogen biosynthetic process2024 rhodopsin biosynthetic process2014

Cellular component: membrane2021, 2024 extracellular region2024 cytoplasm2014

Phylogenetic distribution

Chordates: 19/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 2/8 
Bacteria: 9/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
DHR11_HUMAN
Ensembl»
4.0
DHRS11 Dehydrogenase/reductase SDR family member 11 (17-beta-hydroxysteroid dehydrogenase) (3-beta-hydroxysteroid 3-dehydrogenase) (EC
1.1.1.270) (Estradiol 17-beta-dehydrogenase) (EC 1.1.1.62) (Short-chain dehydrogenase/reductase family 24C member 1)		 Homo sapiens
TI:9606 None
 
Q9VDC0_DROME
FlyBase»
2.0
FOHSDR GH01837p (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform
B (EC 1.1.1.270, EC 1.1.1.62)) (Uncharacterized protein, isoform C)		 Drosophila melanogaster
TI:7227 None
 
DHR11_MOUSE
Ensembl»
0.0
Dhrs11 Dehydrogenase/reductase SDR family member 11 (17-beta-hydroxysteroid dehydrogenase) (3-beta-hydroxysteroid 3-dehydrogenase) (EC
1.1.1.270) (Estradiol 17-beta-dehydrogenase) (EC 1.1.1.62) (Short-chain dehydrogenase/reductase family 24C member 1)		 Mus musculus
TI:10090 None
 
Q5LJT3_DROME
FlyBase»
2.0
CG12466 MIP01391p (Uncharacterized protein, isoform B (EC
1.1.1.270, EC 1.1.1.62)) (Uncharacterized protein, isoform C)		 Drosophila melanogaster
TI:7227 None
 
Q6NNV7_DROME
FlyBase»
2.0
Dmel\CG40485 RH03309p (Uncharacterized protein, isoform B) (Uncharacterized
protein, isoform C (EC 1.1.1.270, EC 1.1.1.62))		 Drosophila melanogaster
TI:7227 None
 
Q9VD30_DROME
FlyBase»
1.6
rdhB GH05294p (Retinol dehydrogenase B, isoform A
(EC 1.1.1.105)) (Retinol dehydrogenase B, isoform B)		 Drosophila melanogaster
TI:7227 None
 
F1QDB3_DANRE
ZFIN»
0.0
zgc:92630 Dehydrogenase/reductase SDR family member
11-like isoform X1 (Zgc:92630)		 Danio rerio
TI:7955 None 		 
 
Q8IRN0_DROME
FlyBase»
2.0
CG7090 FI06485p Drosophila melanogaster
TI:7227 None
 
Q9VYU9_DROME
FlyBase»
2.0
Dmel\CG9360 RH17287p Drosophila melanogaster
TI:7227 None
 
A5WUM7_DANRE
ZFIN»
0.0
zgc:153028 Dehydrogenase/reductase 11a (Dehydrogenase/reductase
SDR family member 11)		 Danio rerio
TI:7955 None 		 
 
DHR11_CHICK
Ensembl»
0.0
DHRS11 Dehydrogenase/reductase SDR family member 11 (17-beta-hydroxysteroid dehydrogenase) (3-beta-hydroxysteroid 3-dehydrogenase) (EC
1.1.1.270) (Estradiol 17-beta-dehydrogenase) (EC 1.1.1.62) (Short-chain dehydrogenase/reductase family 24C member 1)		 Gallus gallus
TI:9031 None
 
F1R5X7_DANRE
ZFIN»
0.0
dhrs11b Dehydrogenase/reductase (SDR family) member 11b Danio rerio
TI:7955 None
 
Q54PT0_DICDI
dictyBase»
0.0
DDB_G0284351 Uncharacterized protein Dictyostelium discoideum
TI:44689 None
 
Q9TYR0_CAEEL
WormBase»
0.0
CELE_H04M03.3 H04M03.3 DeHydrogenases, Short chain Caenorhabditis elegans
TI:6239 None
 
Q9VMH9_DROME
FlyBase»
2.0
Dmel\CG9150 Uncharacterized protein Drosophila melanogaster
TI:7227 None
 
Q9VU92_DROME
FlyBase»
2.0
FOHSDR Uncharacterized protein Drosophila melanogaster
TI:7227 None
 
Q9VZ19_DROME
FlyBase»
2.5
Antdh Antdh (EC 1.-.-.-, EC 1.1.1.270, EC 1.1.1.62) Drosophila melanogaster
TI:7227 None
 
G3V978_RAT
RGD»
2.5
Dhrs11 Dehydrogenase/reductase 11 Rattus norvegicus
TI:10116 None