Collated Gene Ontology terms

Biological process: transcription cis-regulatory region binding(2011, 2021, 2024) Y-form DNA binding(2008, 2017, 2024) chromatin binding(2008, 2014, 2017, 2024) protein-macromolecule adaptor activity(2011, 2024) phosphoprotein binding(2021, 2024) four-way junction DNA binding(2008, 2024) double-stranded DNA binding(2008, 2024) R-SMAD binding(2009, 2024) DNA binding(2015, 2024) sequence-specific DNA binding(2011)
DNA-binding transcription activator activity2021

Molecular function: negative regulation of cell population proliferation2008, 2022, 2024 negative regulation of cell cycle2008, 2021, 2024 regulation of transcription by RNA polymerase II2021, 2024 positive regulation of transcription by RNA polymerase II2008, 2011, 2014, 2021, 2024 negative regulation of transcription by RNA polymerase II2008, 2014, 2016, 2023, 2024 negative regulation of osteoblast differentiation2008, 2024 osteoblast development2008, 2024 transcription initiation-coupled chromatin remodeling2023, 2024 negative regulation of JNK cascade2008, 2024 negative regulation of DNA-templated transcription2004, 2008, 2024
DNA damage response2007, 2008, 2024 response to gamma radiation2008, 2024 response to UV2008, 2024 positive regulation of transforming growth factor beta receptor signaling pathway2008, 2024 T-helper 2 cell differentiation2022, 2024 MAPK cascade2008, 2024 negative regulation of protein phosphorylation2008, 2024 negative regulation of cyclin-dependent protein serine/threonine kinase activity2008, 2024 negative regulation of DNA-binding transcription factor activity2008, 2024 chromatin organization2024 cell population proliferation2008 type B pancreatic cell proliferation2008 stem cell proliferation2008 positive regulation of gene expression2015, 2023 positive regulation of fibroblast apoptotic process2008 negative regulation of type B pancreatic cell proliferation2008 negative regulation of stem cell proliferation2008 fibroblast apoptotic process2008 chromatin remodeling2008 stem cell differentiation2008 roof of mouth development2008 regulation of gene expression2015 regulation of G1/S transition of mitotic cell cycle2021 positive regulation of stem cell differentiation2008 positive regulation of osteoblast differentiation2008 positive regulation of cell division2008 positive regulation of DNA-templated transcription2005 osteoblast fate commitment2008 ossification2008 organ growth2008 negative regulation of organ growth2008 negative regulation of fibroblast proliferation2008 maternal process involved in female pregnancy2008 leukocyte homeostasis2008 hemopoiesis2008 fibroblast proliferation2008 embryonic skeletal system morphogenesis2008 cell division2008 type B pancreatic cell differentiation2014 response to transforming growth factor beta2014 response to salt stress2007 response to oxidative stress2007 response to ionizing radiation2007 response to hypoxia2007 response to heat2007 regulation of type B pancreatic cell proliferation2014 regulation of activin receptor signaling pathway2008 proboscis development2007 positive regulation of JNK cascade2008 nucleotide-excision repair2008 negative regulation of epithelial cell proliferation2014 negative regulation of cell-substrate adhesion2014 negative regulation of cell cycle G1/S phase transition2014 mitotic G1 DNA damage checkpoint signaling2010 interstrand cross-link repair2013 imaginal disc fusion, thorax closure2007 determination of adult lifespan2007 decidualization2014 cellular response to peptide hormone stimulus2014 cellular response to glucose stimulus2014 DNA repair2008

Cellular component: nucleus2005, 2007, 2008, 2009, 2024 histone methyltransferase complex2009, 2021, 2024 chromatin2020, 2021, 2024 transcription repressor complex2016, 2023, 2024 cytosol2006, 2015, 2023, 2024 cytoplasm2008, 2024 MLL1/2 complex2012, 2023, 2024 protein-containing complex2008, 2024 nucleoplasm2012, 2023, 2024 nuclear matrix2008, 2024
cleavage furrow2006, 2024 MLL1 complex2023, 2024 chromosome, telomeric region2016 endoplasmic reticulum lumen2017

Phylogenetic distribution

Chordates: 19/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 10.0 20.0 30.0 40.0 Knownness

Click here to switch to the previous version of the database.


Proteins

UniProt ID
Organism DB»
Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A1S4GXD4_ANOGA
EnsemblMetazoa»
0.0
Menin Anopheles gambiae
TI:7165 None
 
A0A2J8QCL8_PANTR
Ensembl»
0.0
MEN1 Menin Pan troglodytes
TI:9598 None
 
A0A337SU02_FELCA
Ensembl»
0.0
MEN1 Menin Felis catus
TI:9685 None
 
A0A5F5PKC4_HORSE
Ensembl»
0.0
MEN1 Menin Equus caballus
TI:9796 None
   
A0A6I8N6W5_ORNAN
Ensembl»
0.0
MEN1 Menin Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7RH13_STRPU
EnsemblMetazoa»
0.0
Menin Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7T5E0_STRPU
EnsemblMetazoa»
0.0
Menin Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3QHW1_CANLF
Ensembl»
0.0
MEN1 Menin Canis lupus
TI:9612 None
   
A0A8J0PHM0_XENTR
Xenbase»
0.0
men1 Menin Xenopus tropicalis
TI:8364 None
   
A0A9J7NAI3_BRAFL
CTD»
0.0
LOC118430193 Menin Branchiostoma floridae
TI:7739 None
   
A7RZU9_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g241841 Menin Nematostella vectensis
TI:45351 None
 
B1H1W4_XENLA
Xenbase»
0.0
men1.L Menin Xenopus laevis
TI:8355 None
 
B7PJF9_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW004039 Menin Ixodes scapularis
TI:6945 None
 
B8C8D4_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_263558 Menin Thalassiosira pseudonana
TI:35128 None
 
D2A2K0_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_07870 Menin Tribolium castaneum
TI:7070 None
 
E9HIK6_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_63144 Menin Daphnia pulex
TI:6669 None
 
E9HQV9_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_303383 Menin Daphnia pulex
TI:6669 None
 
F1RQR2_PIG
Ensembl»
0.0
MEN1 Menin Sus scrofa
TI:9823 None
 
F6ZBD0_CIOIN
Ensembl»
0.0
LOC104265605 Menin Ciona intestinalis
TI:7719 None
 
G3QKF0_GORGO
Ensembl»
0.0
MEN1 Menin Gorilla gorilla
TI:9593 None
 
H2M806_ORYLA
Ensembl»
0.0
men1 Menin Oryzias latipes
TI:8090 None
   
H9FUK1_MACMU
Ensembl»
0.0
MEN1 Menin Macaca mulatta
TI:9544 None
 
MEN1_BOVIN
Ensembl»
0.0
MEN1 Menin Bos taurus
TI:9913 None
 
MEN1_CANLF
Ensembl»
0.0
MEN1 Menin Canis lupus
TI:9612 None
 
MEN1_HUMAN
Ensembl»
23.6
MEN1 Menin Homo sapiens
TI:9606 None
 
MEN1_MOUSE
Ensembl»
43.9
Men1 Menin Mus musculus
TI:10090 None
 
MEN1_RAT
RGD»
40.4
Men1 Menin Rattus norvegicus
TI:10116 None
 
Q9IAA9_DANRE
ZFIN»
3.8
zgc:110510 Menin Danio rerio
TI:7955 None
 
Q9VM47_DROME
FlyBase»
14.2
Mnn1 Menin Drosophila melanogaster
TI:7227 None
 
T1FFJ3_HELRO
EnsemblMetazoa»
0.0
20207592 Menin Helobdella robusta
TI:6412 None
 
T1FST2_HELRO
EnsemblMetazoa»
0.0
20211879 Menin Helobdella robusta
TI:6412 None
 
T1FVD2_HELRO
EnsemblMetazoa»
0.0
20212778 Menin Helobdella robusta
TI:6412 None
 
W5M217_LEPOC
Ensembl»
0.0
Menin Lepisosteus oculatus
TI:7918 None