Cluster UKP10024
- MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15
Standard knownness: 2.6; Custom knownness: None; Num. species: 34; Orthology database: Panther19.0; Protein members: 61
Collated Gene Ontology terms
Biological process:
transcription coregulator activity(2007, 2025)
zinc ion binding(2025)
metal ion binding(2025)
RNA binding(2025)
Molecular function: regulation of DNA-templated transcription2025 DNA-templated transcription2025 stem cell population maintenance2012 positive regulation of transcription initiation by RNA polymerase II2024, 2025 positive regulation of transcription elongation by RNA polymerase II2024, 2025 RNA polymerase II preinitiation complex assembly2024, 2025 regulation of transcription by RNA polymerase II2020 positive regulation of DNA-templated transcription2024 follicle cell of egg chamber development2015
Cellular component: core mediator complex2024, 2025 nucleus2018, 2024, 2025 nucleoplasm2010, 2013, 2024, 2025 cytoplasm2025 mediator complex2009, 2021 membrane2014
Phylogenetic distribution
| Chordates: | 21/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 0/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 0/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 1/3 | |
| Excavates: | 0/4 | |
| Harosa: | 2/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 1/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
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A0A1L8I0E1_XENLA Xenbase» |
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med15.L | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Xenopus laevis TI:8355 None |
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A0A287AKD0_PIG Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Sus scrofa TI:9823 None |
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A0A2K3CRB3_CHLRE euHCVdb» |
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CHLRE_17g734805v5 | F-box domain-containing protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3CY50_CHLRE euHCVdb» |
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CHLRE_14g623403v5 | Uncharacterized protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D0T3_CHLRE euHCVdb» |
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CHLRE_13g585600v5 | Potassium channel tetramerisation-type BTB domain-containing protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D455_CHLRE euHCVdb» |
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CHLRE_12g521800v5 | Uncharacterized protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D5S9_CHLRE neXtProt» |
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CHLRE_12g556550v5 | Uncharacterized protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D8P9_CHLRE euHCVdb» |
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CHLRE_11g480551v5 | Uncharacterized protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3DFD2_CHLRE euHCVdb» |
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CHLRE_09g407120v5 | Uncharacterized protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3DZ79_CHLRE euHCVdb» |
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CHLRE_03g203100v5 | Uncharacterized protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3E2L2_CHLRE euHCVdb» |
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CHLRE_02g105250v5 | Uncharacterized protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3E3D5_CHLRE euHCVdb» |
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CHLRE_02g117100v5 | Uncharacterized protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3E8C1_CHLRE euHCVdb» |
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CHLRE_01g055350v5 | Uncharacterized protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A3B3HED2_ORYLA Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Oryzias latipes TI:8090 None |
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A0A3B3IH37_ORYLA Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Oryzias latipes TI:8090 None |
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A0A5F8HK71_MONDO Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Monodelphis domestica TI:13616 None |
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A0A6I8PL92_ORNAN Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Ornithorhynchus anatinus TI:9258 None |
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A0A7M7N7H2_STRPU EnsemblMetazoa» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Strongylocentrotus purpuratus TI:7668 None |
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A0A7M7P6P6_STRPU EnsemblMetazoa» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Strongylocentrotus purpuratus TI:7668 None |
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A0A7M7P809_STRPU EnsemblMetazoa» |
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Mediator complex subunit 15 |
Strongylocentrotus purpuratus TI:7668 None |
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A0A8I3PQB3_CANLF Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Canis lupus TI:9612 None |
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A0A8J0QZN9_XENTR Xenbase» |
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med15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Xenopus tropicalis TI:8364 None |
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A0A8J0U1Y6_XENLA Xenbase» |
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med15.S | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Xenopus laevis TI:8355 None |
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A0A8V1AD23_CHICK Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Gallus gallus TI:9031 None |
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A0A9J7LZK8_BRAFL euHCVdb» |
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LOC118426117 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Branchiostoma floridae TI:7739 None |
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A0AAA9SHM7_BOVIN Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Bos taurus TI:9913 None |
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A0ABI8A623_FELCA Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Felis catus TI:9685 None |
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A0ABK0LFT4_RAT RGD» |
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Med15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Rattus norvegicus TI:10116 None |
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A0BBQ9_PARTE euHCVdb» |
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GSPATT00000411001 | PHD-type domain-containing protein |
Paramecium tetraurelia TI:5888 None |
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A0CJM8_PARTE euHCVdb» |
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GSPATT00000707001 | PHD-type domain-containing protein |
Paramecium tetraurelia TI:5888 None |
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A0E6D9_PARTE euHCVdb» |
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GSPATT00003721001 | PHD-type domain-containing protein |
Paramecium tetraurelia TI:5888 None |
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A7S2Y6_NEMVE euHCVdb» |
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NEMVEDRAFT_v1g102638 | Uncharacterized protein |
Nematostella vectensis TI:45351 None |
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B3S4L1_TRIAD CTD» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Trichoplax adhaerens TI:10228 None |
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B7Q503_IXOSC EnsemblMetazoa» |
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IscW_ISCW010764 | Positive cofactor 2, subunit of a RNA polymerase II multiprotein coactivator, putative |
Ixodes scapularis TI:6945 None |
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D6WKC9_TRICA euHCVdb» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Tribolium castaneum TI:7070 None |
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E9H9W0_DAPPU neXtProt» |
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DAPPUDRAFT_60117 | Uncharacterized protein |
Daphnia pulex TI:6669 None |
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E9I517_DAPPU neXtProt» |
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DAPPUDRAFT_341016 | ARC105/Med15 mediator subunit central domain-containing protein |
Daphnia pulex TI:6669 None |
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F6PL34_ORNAN Ensembl» |
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Uncharacterized protein |
Ornithorhynchus anatinus TI:9258 None |
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F6QGI0_MACMU Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Macaca mulatta TI:9544 None |
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F6SWM7_CIOIN Ensembl» |
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Uncharacterized protein |
Ciona intestinalis TI:7719 None |
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F6Z710_HORSE Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Equus caballus TI:9796 None |
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G3S027_GORGO Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Gorilla gorilla TI:9593 None |
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H2QZT1_PANTR Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Pan troglodytes TI:9598 None |
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K7E9T9_ORNAN Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Ornithorhynchus anatinus TI:9258 None |
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MED15_ANOGA EnsemblMetazoa» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Anopheles gambiae TI:7165 None |
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MED15_DANRE ZFIN» |
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med15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Danio rerio TI:7955 None |
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MED15_DROME FlyBase» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) (dARC105) |
Drosophila melanogaster TI:7227 None |
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MED15_HUMAN Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a) (Mediator complex subunit 15) (Positive cofactor 2 glutamine/Q-rich-associated protein) (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Trinucleotide repeat-containing gene 7 protein) |
Homo sapiens TI:9606 None |
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MED15_MOUSE Ensembl» |
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Med15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) (Positive cofactor 2 glutamine/Q-rich-associated protein) (PC2 glutamine/Q-rich-associated protein) (mPcqap) |
Mus musculus TI:10090 None |
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MED15_XENLA Xenbase» |
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med15 | Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (xARC105) (Mediator complex subunit 15) |
Xenopus laevis TI:8355 None |
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Q557F5_DICDI dictyBase» |
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DDB_G0273391 DDB_G0273593 | DDE Tnp4 domain-containing protein |
Dictyostelium discoideum TI:44689 None |
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Q6BG97_PARTE euHCVdb» |
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PTMB.125 | PHD-type domain-containing protein |
Paramecium tetraurelia TI:5888 None |
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Q8I515_PLAF7 TubercuList» |
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PF3D7_1241400 | RNA-binding protein, putative |
Plasmodium falciparum TI:5833 None |
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Q8I5J4_PLAF7 TubercuList» |
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PF3D7_1221900 | Uncharacterized protein |
Plasmodium falciparum TI:5833 None |
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Q8IIV9_PLAF7 TubercuList» |
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PF3D7_1104300 | Uncharacterized protein |
Plasmodium falciparum TI:5833 None |
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Q8IJD3_PLAF7 TubercuList» |
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PF3D7_1027000 | Uncharacterized protein |
Plasmodium falciparum TI:5833 None |
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T1EZM1_HELRO EnsemblMetazoa» |
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20202021 | Uncharacterized protein |
Helobdella robusta TI:6412 None |
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T1F2J8_HELRO EnsemblMetazoa» |
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20203048 | Sema domain-containing protein |
Helobdella robusta TI:6412 None |
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T1FIY4_HELRO EnsemblMetazoa» |
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20208783 | PID domain-containing protein |
Helobdella robusta TI:6412 None |
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T1FNI9_HELRO EnsemblMetazoa» |
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20210386 | Uncharacterized protein |
Helobdella robusta TI:6412 None |
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W5MHF7_LEPOC Ensembl» |
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MED15 | Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) |
Lepisosteus oculatus TI:7918 None |
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