Collated Gene Ontology terms

Biological process: transcription coregulator activity(2007, 2025) zinc ion binding(2025) metal ion binding(2025) RNA binding(2025)

Molecular function: regulation of DNA-templated transcription2025 DNA-templated transcription2025 stem cell population maintenance2012 positive regulation of transcription initiation by RNA polymerase II2024, 2025 positive regulation of transcription elongation by RNA polymerase II2024, 2025 RNA polymerase II preinitiation complex assembly2024, 2025 regulation of transcription by RNA polymerase II2020 positive regulation of DNA-templated transcription2024 follicle cell of egg chamber development2015

Cellular component: core mediator complex2024, 2025 nucleus2018, 2024, 2025 nucleoplasm2010, 2013, 2024, 2025 cytoplasm2025 mediator complex2009, 2021 membrane2014

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 1/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
MED15_DANRE
ZFIN»
0.0
med15 Mediator of RNA polymerase II transcription
subunit 15 (Mediator complex subunit 15)		 Danio rerio
TI:7955 None
 
Q557F5_DICDI
dictyBase»
0.0
DDB_G0273391 DDB_G0273593 DDE Tnp4 domain-containing protein Dictyostelium discoideum
TI:44689 None
   
MED15_DROME
FlyBase»
2.4
MED15 Mediator of RNA polymerase II transcription
subunit 15 (Mediator complex subunit 15) (dARC105)		 Drosophila melanogaster
TI:7227 None
 
A0A8V1AD23_CHICK
Ensembl»
0.0
MED15 Mediator of RNA polymerase II transcription
subunit 15 (Mediator complex subunit 15)		 Gallus gallus
TI:9031 None
   
MED15_HUMAN
Ensembl»
1.8
MED15 Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a) (Mediator complex
subunit 15) (Positive cofactor 2 glutamine/Q-rich-associated protein) (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Trinucleotide repeat-containing gene 7 protein)		 Homo sapiens
TI:9606 None
 
MED15_MOUSE
Ensembl»
2.6
Med15 Mediator of RNA polymerase II transcription subunit 15 (Mediator complex
subunit 15) (Positive cofactor 2 glutamine/Q-rich-associated protein) (PC2 glutamine/Q-rich-associated protein) (mPcqap)		 Mus musculus
TI:10090 None
 
A0ABK0LFT4_RAT
RGD»
0.5
Med15 Mediator of RNA polymerase II transcription
subunit 15 (Mediator complex subunit 15)		 Rattus norvegicus
TI:10116 None