Collated Gene Ontology terms

Biological process: N-acylneuraminate-9-phosphate synthase activity(2006, 2024, 2025) transferase activity(2025) metal ion binding(2025) N-acetylneuraminate synthase activity(2025)

Molecular function: carbohydrate biosynthetic process2025 N-acetylneuraminate metabolic process2024, 2025 CMP-N-acetylneuraminate biosynthetic process2017, 2024, 2025 carbohydrate derivative biosynthetic process2025 N-acetylneuraminate biosynthetic process2024, 2025 embryonic skeletal system development2016

Cellular component: cytosol2013, 2024, 2025 nucleoplasm2024, 2025 extracellular region2025 cytoplasm2001, 2025 extracellular exosome2014

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 3/8 
Bacteria: 12/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
SIAS_HUMAN
Ensembl»
4.4
NANS N-acetylneuraminate-9-phosphate synthase (EC 2.5.1.57) (3-deoxy-D-glycero-D-galacto-nononate 9-phosphate synthase) (EC 2.5.1.132) (N-acetylneuraminic
acid phosphate synthase) (NANS) (Sialic acid phosphate synthase) (Sialic acid synthase)		 Homo sapiens
TI:9606 None
 
SIAS_MOUSE
Ensembl»
3.6
Nans N-acetylneuraminate-9-phosphate synthase (EC 2.5.1.57) (N-acetylneuraminic
acid phosphate synthase) (Sialic acid synthase)		 Mus musculus
TI:10090 None
 
SIAS_DROME
FlyBase»
2.6
Nans N-acetylneuraminate-9-phosphate synthase (EC 2.5.1.57) (3-deoxy-D-glycero-D-galacto-nononate 9-phosphate
synthase) (EC 2.5.1.132) (Sialic acid synthase)		 Drosophila melanogaster
TI:7227 None
 
Q5U3W7_DANRE
ZFIN»
0.5
nansb N-acetylneuraminate-9-phosphate synthase (EC
2.5.1.57) (Sialic acid synthase)		 Danio rerio
TI:7955 None
 
Q5ZMH8_CHICK
Ensembl»
0.5
NANS N-acetylneuraminate-9-phosphate synthase (EC
2.5.1.57) (Sialic acid synthase)		 Gallus gallus
TI:9031 None
 
Q6P0K4_DANRE
ZFIN»
1.3
nansa N-acetylneuraminate-9-phosphate synthase (EC
2.5.1.57) (Sialic acid synthase)		 Danio rerio
TI:7955 None
 
B1WC26_RAT
RGD»
2.5
Nans N-acetylneuraminate-9-phosphate synthase (EC 2.5.1.57) (N-acetylneuraminic
acid phosphate synthase) (Sialic acid synthase)		 Rattus norvegicus
TI:10116 None