Cluster UKP10010
- N-ACETYLNEURAMINATE SYNTHASE
Standard knownness: 5.7; Custom knownness: None; Num. species: 42; Orthology database: Panther19.0; Protein members: 49
Collated Gene Ontology terms
Biological process:
N-acylneuraminate-9-phosphate synthase activity(2006, 2009, 2020, 2024)
transferase activity(2024)
N-acetylneuraminate synthase activity(2024)
metal ion binding(2024)
Molecular function: glycosylation2012, 2024 carbohydrate biosynthetic process2024 CMP-N-acetylneuraminate biosynthetic process2017, 2024 N-acetylneuraminate biosynthetic process2024 protein glycosylation2023 embryonic skeletal system development2016
Cellular component: cytosol2001, 2013, 2024 extracellular region2024 cytoplasm2001, 2024 extracellular exosome2014
Phylogenetic distribution
| Chordates: | 21/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 0/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 0/3 | |
| Arthropods: | 4/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 0/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 0/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 0/3 | |
| Excavates: | 0/4 | |
| Harosa: | 0/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 3/8 | |
| Bacteria: | 12/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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A0A287B0V1_PIG Ensembl» |
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NANS | N-acetylneuraminate synthase |
Sus scrofa TI:9823 None |
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A0A2I2Y964_GORGO Ensembl» |
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NANS | N-acetylneuraminate synthase |
Gorilla gorilla TI:9593 None |
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A0A337SJK9_FELCA Ensembl» |
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NANS | N-acetylneuraminate synthase |
Felis catus TI:9685 None |
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A0A5F8AFA3_MACMU Ensembl» |
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NANS | N-acetylneuraminate synthase |
Macaca mulatta TI:9544 None |
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A0A7M7SYX7_STRPU EnsemblMetazoa» |
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AFP-like domain-containing protein |
Strongylocentrotus purpuratus TI:7668 None |
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A0A8I3N2X1_CANLF Ensembl» |
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NANS | N-acetylneuraminate synthase |
Canis lupus TI:9612 None |
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A0A9J7KY42_BRAFL CTD» |
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LOC118412951 | Sialic acid synthase-like |
Branchiostoma floridae TI:7739 None |
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A5I5B4_CLOBH Ensembl» |
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CBO2680 | N-acetyl neuramic acid synthetase |
Clostridium botulinum TI:1491 None |
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A5I5F4_CLOBH Ensembl» |
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CBO2720 | N-acetylneuraminic acid synthetase |
Clostridium botulinum TI:1491 None |
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A7TBE0_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g7984 | N-acetylneuraminic acid synthase N-terminal domain-containing protein |
Nematostella vectensis TI:45351 None |
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A9A1R0_NITMS EnsemblBacteria» |
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Nmar_0131 | N-acylneuraminate-9-phosphate synthase (EC 2.5.1.57) |
Nitrosopumilus maritimus TI:338192 None |
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B1WC26_RAT RGD» |
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Nans | N-acetylneuraminate synthase |
Rattus norvegicus TI:10116 None |
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B5YJA9_THEYD EnsemblBacteria» |
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THEYE_A0479 | CMP-NeuNAc synthetase |
Thermodesulfovibrio yellowstonii TI:28262 None |
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C3YJ26_BRAFL CTD» |
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LOC118412952 | Sialic acid synthase-like |
Branchiostoma floridae TI:7739 None |
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D6WCA5_TRICA EnsemblMetazoa» |
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AUGUSTUS-3.0.2_00193 | Sialic acid synthase-like Protein |
Tribolium castaneum TI:7070 None |
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E9HZY6_DAPPU EnsemblMetazoa» |
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DAPPUDRAFT_300651 | AFP-like domain-containing protein |
Daphnia pulex TI:6669 None |
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F6SJ79_MONDO Ensembl» |
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NANS | N-acetylneuraminate synthase |
Monodelphis domestica TI:13616 None |
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F6YM24_HORSE Ensembl» |
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NANS | N-acetylneuraminate synthase |
Equus caballus TI:9796 None |
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F7BVV6_XENTR Xenbase» |
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nans | N-acetylneuraminate synthase (Sialic acid synthase) |
Xenopus tropicalis TI:8364 None |
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F7DGK6_ORNAN Ensembl» |
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NANS | N-acetylneuraminate synthase |
Ornithorhynchus anatinus TI:9258 None |
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H2N2T5_ORYLA Ensembl» |
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nans | N-acetylneuraminate synthase |
Oryzias latipes TI:8090 None |
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H2QXJ8_PANTR Ensembl» |
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NANS | N-acetylneuraminate synthase |
Pan troglodytes TI:9598 None |
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H9G5W6_ANOCA Ensembl» |
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nans | AFP-like domain-containing protein |
Anolis carolinensis TI:28377 None |
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PSEI_HELPY EnsemblBacteria» |
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pseI | Pseudaminic acid synthase (EC 2.5.1.97) (Pseudaminic acid biosynthesis protein I) |
Helicobacter pylori TI:210 None |
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Q1RMX7_BOVIN Ensembl» |
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NANS | N-acetylneuraminate synthase (N-acetylneuraminic acid synthase) |
Bos taurus TI:9913 None |
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Q5U3W7_DANRE ZFIN» |
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nansb | Uncharacterized protein LOC492779 (Zgc:101549) |
Danio rerio TI:7955 None |
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Q5ZMH8_CHICK Ensembl» |
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NANS | N-acetylneuraminate synthase |
Gallus gallus TI:9031 None |
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Q66KH0_XENLA Xenbase» |
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nans.L | MGC84329 protein (N-acetylneuraminate synthase L homeolog) |
Xenopus laevis TI:8355 None |
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Q6IRP2_XENLA Xenbase» |
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nans.S | MGC83164 protein (Uncharacterized protein LOC432051) |
Xenopus laevis TI:8355 None |
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Q6P0K4_DANRE ZFIN» |
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zgc:77126 | Sialic acid synthase (Zgc:77126) |
Danio rerio TI:7955 None |
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Q74B32_GEOSL EnsemblBacteria» |
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neuB | N-acetylneuraminate synthase |
Geobacter sulfurreducens TI:35554 None |
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Q7DDU0_NEIMB EnsemblBacteria» |
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siaC | Polysialic acid capsule biosynthesis protein SiaC |
Neisseria meningitidis TI:487 None |
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Q7PQ63_ANOGA EnsemblMetazoa» |
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1274606 | AGAP004460-PA |
Anopheles gambiae TI:7165 None |
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Q89HJ8_BRADU EnsemblBacteria» |
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blr5992 | Blr5992 protein |
Bradyrhizobium diazoefficiens TI:1355477 None |
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Q89HL9_BRADU EnsemblBacteria» |
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blr5971 | Blr5971 protein |
Bradyrhizobium diazoefficiens TI:1355477 None |
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Q8A711_BACTN EnsemblBacteria» |
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BT_1714 | Sialic acid synthase (N-acetylneuraminate synthase) |
Bacteroides thetaiotaomicron TI:818 None |
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Q8EC83_SHEON EnsemblPlants» |
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SO_3261 | Polysaccharide biosynthesis related-protein |
Shewanella oneidensis TI:70863 None |
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Q8F330_LEPIN EnsemblBacteria» |
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spsE | N-acetylneuraminic (Sialic) acid synthetase |
Leptospira interrogans TI:173 None |
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Q8F5Q4_LEPIN EnsemblBacteria» |
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spsE | N-acetylneuraminic (Sialic) acid synthetase |
Leptospira interrogans TI:173 None |
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Q8F5Q8_LEPIN EnsemblBacteria» |
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spsE | N-acetylneuraminic (Sialic) acid synthetase |
Leptospira interrogans TI:173 None |
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Q8RIB8_FUSNN EnsemblBacteria» |
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FN1684 | N-acetylneuraminate synthase (EC 2.5.1.56) |
Fusobacterium nucleatum TI:851 None |
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Q8TJL5_METAC EnsemblBacteria» |
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MA_3767 | N-acetylneuraminic acid phosphate synthase |
Methanosarcina acetivorans TI:2214 None |
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Q9AK45_STRCO EnsemblBacteria» |
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SCO4881 | Polysaccharide biosynthesis related protein |
Streptomyces coelicolor TI:1902 None |
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SIAS_DROME FlyBase» |
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NANS | Sialic acid synthase (N-acetylneuraminate synthase) (EC 2.5.1.56) (N-acetylneuraminate-9-phosphate synthase) (EC 2.5.1.57) |
Drosophila melanogaster TI:7227 None |
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SIAS_HUMAN Ensembl» |
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NANS | Sialic acid synthase (N-acetylneuraminate synthase) (EC 2.5.1.56) (N-acetylneuraminate-9-phosphate synthase) (EC 2.5.1.57) (N-acetylneuraminic acid phosphate synthase) (N-acetylneuraminic acid synthase) |
Homo sapiens TI:9606 None |
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SIAS_MOUSE Ensembl» |
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Nans | Sialic acid synthase (N-acetylneuraminate-9-phosphate synthase) (EC 2.5.1.57) (N-acetylneuraminic acid phosphate synthase) |
Mus musculus TI:10090 None |
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SPSE_BACSU EnsemblBacteria» |
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spsE | Spore coat polysaccharide biosynthesis protein SpsE |
Bacillus subtilis TI:1423 None |
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W5MZB9_LEPOC Ensembl» |
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N-acetylneuraminate synthase |
Lepisosteus oculatus TI:7918 None |
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Y1065_METJA EnsemblBacteria» |
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MJ1065 | Uncharacterized protein MJ1065 |
Methanocaldococcus jannaschii TI:2190 None |
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