Collated Gene Ontology terms

Biological process: N-acylneuraminate-9-phosphate synthase activity(2006, 2009, 2020, 2024) transferase activity(2024) N-acetylneuraminate synthase activity(2024) metal ion binding(2024)

Molecular function: glycosylation2012, 2024 carbohydrate biosynthetic process2024 CMP-N-acetylneuraminate biosynthetic process2017, 2024 N-acetylneuraminate biosynthetic process2024 protein glycosylation2023 embryonic skeletal system development2016

Cellular component: cytosol2001, 2013, 2024 extracellular region2024 cytoplasm2001, 2024 extracellular exosome2014

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 3/8 
Bacteria: 12/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
H9G5W6_ANOCA
Ensembl»
0.0
nans AFP-like domain-containing protein Anolis carolinensis
TI:28377 None
   
Q7PQ63_ANOGA
EnsemblMetazoa»
0.0
1274606 AGAP004460-PA Anopheles gambiae
TI:7165 None
 
SPSE_BACSU
EnsemblBacteria»
0.0
spsE Spore coat polysaccharide
biosynthesis protein SpsE		 Bacillus subtilis
TI:1423 None
 
Q8A711_BACTN
EnsemblBacteria»
0.0
BT_1714 Sialic acid
synthase (N-acetylneuraminate synthase)		 Bacteroides thetaiotaomicron
TI:818 None
 
Q1RMX7_BOVIN
Ensembl»
0.0
NANS N-acetylneuraminate synthase
(N-acetylneuraminic acid synthase)		 Bos taurus
TI:9913 None
 
Q89HJ8_BRADU
EnsemblBacteria»
0.0
blr5992 Blr5992 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
Q89HL9_BRADU
EnsemblBacteria»
0.0
blr5971 Blr5971 protein Bradyrhizobium diazoefficiens
TI:1355477 None
 
A0A9J7KY42_BRAFL
CTD»
0.0
LOC118412951 Sialic acid synthase-like Branchiostoma floridae
TI:7739 None
   
C3YJ26_BRAFL
CTD»
0.0
LOC118412952 Sialic acid synthase-like Branchiostoma floridae
TI:7739 None
 
A0A8I3N2X1_CANLF
Ensembl»
0.0
NANS N-acetylneuraminate synthase Canis lupus
TI:9612 None
   
A5I5B4_CLOBH
Ensembl»
0.0
CBO2680 N-acetyl neuramic acid synthetase Clostridium botulinum
TI:1491 None
 
A5I5F4_CLOBH
Ensembl»
0.0
CBO2720 N-acetylneuraminic acid synthetase Clostridium botulinum
TI:1491 None
 
Q5U3W7_DANRE
ZFIN»
0.0
nansb Uncharacterized protein LOC492779 (Zgc:101549) Danio rerio
TI:7955 None
 
Q6P0K4_DANRE
ZFIN»
1.8
zgc:77126 Sialic acid synthase (Zgc:77126) Danio rerio
TI:7955 None
 
E9HZY6_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_300651 AFP-like domain-containing protein Daphnia pulex
TI:6669 None
 
SIAS_DROME
FlyBase»
4.7
NANS Sialic acid synthase (N-acetylneuraminate synthase)
(EC 2.5.1.56) (N-acetylneuraminate-9-phosphate synthase) (EC 2.5.1.57)		 Drosophila melanogaster
TI:7227 None
 
F6YM24_HORSE
Ensembl»
0.0
NANS N-acetylneuraminate synthase Equus caballus
TI:9796 None
   
A0A337SJK9_FELCA
Ensembl»
0.0
NANS N-acetylneuraminate synthase Felis catus
TI:9685 None
 
Q8RIB8_FUSNN
EnsemblBacteria»
0.0
FN1684 N-acetylneuraminate synthase (EC 2.5.1.56) Fusobacterium nucleatum
TI:851 None
 
Q5ZMH8_CHICK
Ensembl»
1.0
NANS N-acetylneuraminate synthase Gallus gallus
TI:9031 None
 
Q74B32_GEOSL
EnsemblBacteria»
0.0
neuB N-acetylneuraminate synthase Geobacter sulfurreducens
TI:35554 None
 
A0A2I2Y964_GORGO
Ensembl»
0.0
NANS N-acetylneuraminate synthase Gorilla gorilla
TI:9593 None
 
PSEI_HELPY
EnsemblBacteria»
0.0
pseI Pseudaminic acid synthase (EC 2.5.1.97)
(Pseudaminic acid biosynthesis protein I)		 Helicobacter pylori
TI:210 None
 
SIAS_HUMAN
Ensembl»
5.7
NANS Sialic acid synthase (N-acetylneuraminate synthase) (EC 2.5.1.56) (N-acetylneuraminate-9-phosphate synthase)
(EC 2.5.1.57) (N-acetylneuraminic acid phosphate synthase) (N-acetylneuraminic acid synthase)		 Homo sapiens
TI:9606 None
 
W5MZB9_LEPOC
Ensembl»
0.0
N-acetylneuraminate synthase Lepisosteus oculatus
TI:7918 None
 
Q8F330_LEPIN
EnsemblBacteria»
0.0
spsE N-acetylneuraminic (Sialic) acid synthetase Leptospira interrogans
TI:173 None
 
Q8F5Q4_LEPIN
EnsemblBacteria»
0.0
spsE N-acetylneuraminic (Sialic) acid synthetase Leptospira interrogans
TI:173 None
 
Q8F5Q8_LEPIN
EnsemblBacteria»
0.0
spsE N-acetylneuraminic (Sialic) acid synthetase Leptospira interrogans
TI:173 None
 
A0A5F8AFA3_MACMU
Ensembl»
0.0
NANS N-acetylneuraminate synthase Macaca mulatta
TI:9544 None
   
Y1065_METJA
EnsemblBacteria»
0.0
MJ1065 Uncharacterized protein MJ1065 Methanocaldococcus jannaschii
TI:2190 None
 
Q8TJL5_METAC
EnsemblBacteria»
0.0
MA_3767 N-acetylneuraminic acid phosphate synthase Methanosarcina acetivorans
TI:2214 None
 
F6SJ79_MONDO
Ensembl»
0.0
NANS N-acetylneuraminate synthase Monodelphis domestica
TI:13616 None
   
SIAS_MOUSE
Ensembl»
0.8
Nans Sialic acid synthase (N-acetylneuraminate-9-phosphate synthase)
(EC 2.5.1.57) (N-acetylneuraminic acid phosphate synthase)		 Mus musculus
TI:10090 None
 
Q7DDU0_NEIMB
EnsemblBacteria»
0.0
siaC Polysialic acid capsule
biosynthesis protein SiaC		 Neisseria meningitidis
TI:487 None
 
A7TBE0_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g7984 N-acetylneuraminic acid synthase
N-terminal domain-containing protein		 Nematostella vectensis
TI:45351 None
 
A9A1R0_NITMS
EnsemblBacteria»
0.0
Nmar_0131 N-acylneuraminate-9-phosphate synthase
(EC 2.5.1.57)		 Nitrosopumilus maritimus
TI:338192 None
 
F7DGK6_ORNAN
Ensembl»
0.0
NANS N-acetylneuraminate synthase Ornithorhynchus anatinus
TI:9258 None
   
H2N2T5_ORYLA
Ensembl»
0.0
nans N-acetylneuraminate synthase Oryzias latipes
TI:8090 None
   
H2QXJ8_PANTR
Ensembl»
0.0
NANS N-acetylneuraminate synthase Pan troglodytes
TI:9598 None
 
B1WC26_RAT
RGD»
1.5
Nans N-acetylneuraminate synthase Rattus norvegicus
TI:10116 None
   
Q8EC83_SHEON
EnsemblPlants»
0.0
SO_3261 Polysaccharide biosynthesis related-protein Shewanella oneidensis
TI:70863 None
 
Q9AK45_STRCO
EnsemblBacteria»
0.0
SCO4881 Polysaccharide biosynthesis related protein Streptomyces coelicolor
TI:1902 None
 
A0A7M7SYX7_STRPU
EnsemblMetazoa»
0.0
AFP-like domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A287B0V1_PIG
Ensembl»
0.0
NANS N-acetylneuraminate synthase Sus scrofa
TI:9823 None
   
B5YJA9_THEYD
EnsemblBacteria»
0.0
THEYE_A0479 CMP-NeuNAc synthetase Thermodesulfovibrio yellowstonii
TI:28262 None
 
D6WCA5_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_00193 Sialic acid synthase-like Protein Tribolium castaneum
TI:7070 None
 
F7BVV6_XENTR
Xenbase»
0.0
nans N-acetylneuraminate synthase
(Sialic acid synthase)		 Xenopus tropicalis
TI:8364 None
   
Q66KH0_XENLA
Xenbase»
0.0
nans.L MGC84329 protein (N-acetylneuraminate
synthase L homeolog)		 Xenopus laevis
TI:8355 None
 
Q6IRP2_XENLA
Xenbase»
0.0
nans.S MGC83164 protein
(Uncharacterized protein LOC432051)		 Xenopus laevis
TI:8355 None