Cluster UKP10005
- LIPOATE-PROTEIN LIGASE
Standard knownness: 4.2; Custom knownness: None; Num. species: 64; Orthology database: Panther19.0; Protein members: 68
Collated Gene Ontology terms
Biological process:
lipoyltransferase activity(2011, 2012, 2016, 2023, 2024)
lipoate-protein ligase activity(2008, 2011, 2013, 2014, 2016, 2021, 2024)
ligase activity(2024)
ATP binding(2024)
acyltransferase activity(2024)
transferase activity(2024)
metal ion binding(2024)
catalytic activity(2014)
N-acyltransferase activity(2024)
Molecular function: protein lipoylation2011, 2014, 2016, 2024 lipid metabolic process2003, 2007 protein modification process2003 protein maturation2017 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021
Cellular component: cytoplasm2009, 2023, 2024 mitochondrion2009, 2013, 2014, 2020, 2024 cytosol2014, 2021 mitochondrial matrix2015
Phylogenetic distribution
| Chordates: | 19/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 2/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 13/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 3/4 | |
| Harosa: | 2/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 1/39 | |
| Archea: | 1/8 | |
| Bacteria: | 12/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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A0A6I8NHL2_ORNAN Ensembl» |
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LIPT1 | BPL/LPL catalytic domain-containing protein |
Ornithorhynchus anatinus TI:9258 None |
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A0A7M7P367_STRPU EnsemblMetazoa» |
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BPL/LPL catalytic domain-containing protein |
Strongylocentrotus purpuratus TI:7668 None |
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A0A8R1V2D9_PRIPA EnsemblMetazoa» |
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WBGene00304332 | BPL/LPL catalytic domain-containing protein |
Pristionchus pacificus TI:54126 None |
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A7RGY5_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g81677 | BPL/LPL catalytic domain-containing protein |
Nematostella vectensis TI:45351 None |
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B3RK56_TRIAD EnsemblMetazoa» |
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TRIADDRAFT_51631 | BPL/LPL catalytic domain-containing protein |
Trichoplax adhaerens TI:10228 None |
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E9FUZ6_DAPPU EnsemblMetazoa» |
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DAPPUDRAFT_311204 | BPL/LPL catalytic domain-containing protein |
Daphnia pulex TI:6669 None |
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F6VMC6_CIOIN Ensembl» |
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BPL/LPL catalytic domain-containing protein |
Ciona intestinalis TI:7719 None |
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O45303_CAEEL WormBase» |
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lipt-1 | BPL/LPL catalytic domain-containing protein |
Caenorhabditis elegans TI:6239 None |
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T1FN43_HELRO EnsemblMetazoa» |
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20210241 | BPL/LPL catalytic domain-containing protein |
Helobdella robusta TI:6412 None |
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Q8SX78_DROME FlyBase» |
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Lipt1 | LD05679p (LD22815p) (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B) |
Drosophila melanogaster TI:7227 None |
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LIPLA_PLAF7 EnsemblProtists» |
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LipL1 | Lipoate--protein ligase 1 (EC 6.3.1.20) |
Plasmodium falciparum TI:5833 None |
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LPLA_ECOLI EnsemblBacteria» |
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lplA | Lipoate-protein ligase A (EC 6.3.1.20) (Lipoate--protein ligase) |
Escherichia coli TI:562 None |
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LPLA_SALTY EnsemblBacteria» |
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lplA | Lipoate-protein ligase A (EC 6.3.1.20) (Lipoate--protein ligase) |
Salmonella typhimurium TI:28901 None |
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LPLA_VIBCH EnsemblBacteria» |
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lplA | Lipoate-protein ligase A (EC 6.3.1.20) (Lipoate--protein ligase) |
Vibrio cholerae TI:666 None |
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LPLA_YERPE EnsemblBacteria» |
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lplA | Lipoate-protein ligase A (EC 6.3.1.20) (Lipoate--protein ligase) |
Yersinia pestis TI:632 None |
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Q8AB02_BACTN EnsemblBacteria» |
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BT_0310 | Lipoate-protein ligase A |
Bacteroides thetaiotaomicron TI:818 None |
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Q97U65_SACS2 EnsemblBacteria» |
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lplA-1 | Lipoate-protein ligase A (LplA-1) |
Saccharolobus solfataricus TI:2287 None |
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LPLJ_BACSU EnsemblBacteria» |
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lplJ | Lipoate-protein ligase LplJ (EC 6.3.1.20) (Lipoate--protein ligase) |
Bacillus subtilis TI:1423 None |
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B7Q697_IXOSC EnsemblMetazoa» |
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8036505 | Lipoate-protein ligase, putative |
Ixodes scapularis TI:6945 None |
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Q57YG7_TRYB2 VEuPathDB» |
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Tb08.12O16.190 | Lipoate-protein ligase, putative (EC 6.-.-.-) |
Trypanosoma brucei TI:5691 None |
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A0A2I2U9H5_FELCA Ensembl» |
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LIPT1 | Lipoyltransferase 1 |
Felis catus TI:9685 None |
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A0A8I3PAB4_CANLF Ensembl» |
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LIPT1 | Lipoyltransferase 1 |
Canis lupus TI:9612 None |
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A0A8V0YTB2_CHICK Ensembl» |
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LIPT1 | Lipoyltransferase 1 |
Gallus gallus TI:9031 None |
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D3Z7Z4_RAT RGD» |
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Lipt1 | Lipoyltransferase 1 |
Rattus norvegicus TI:10116 None |
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F7ARC0_MONDO Ensembl» |
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LIPT1 | Lipoyltransferase 1 |
Monodelphis domestica TI:13616 None |
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G3S0M5_GORGO Ensembl» |
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LIPT1 | Lipoyltransferase 1 |
Gorilla gorilla TI:9593 None |
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H2L7T5_ORYLA Ensembl» |
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lipt1 | Lipoyltransferase 1 |
Oryzias latipes TI:8090 None |
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H2QIE7_PANTR Ensembl» |
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LIPT1 | Lipoyltransferase 1 |
Pan troglodytes TI:9598 None |
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H9G4E9_ANOCA Ensembl» |
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LIPT1 | Lipoyltransferase 1 |
Anolis carolinensis TI:28377 None |
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W5NML4_LEPOC Ensembl» |
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Lipoyltransferase 1 |
Lepisosteus oculatus TI:7918 None |
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F6RNJ0_XENTR Xenbase» |
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lipt1 | Lipoyltransferase 1 (Lipoyltransferase 1, mitochondrial isoform X1) |
Xenopus tropicalis TI:8364 None |
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A0A1L8HGT8_XENLA Xenbase» |
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lipt1.L | Lipoyltransferase 1 L homeolog isoform X1 |
Xenopus laevis TI:8355 None |
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Q08CP2_DANRE ZFIN» |
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zgc:152851 | Lipoyltransferase 1, mitochondrial (EC 2.3.1.181) (Zgc:152851) |
Danio rerio TI:7955 None |
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LIPT_BOVIN Ensembl» |
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LIPT1 | Lipoyltransferase 1, mitochondrial (EC 2.3.1.-) (Lipoate biosynthesis protein) (Lipoate-protein ligase) (Lipoyl ligase) |
Bos taurus TI:9913 None |
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LIPT_HUMAN Ensembl» |
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LIPT1 | Lipoyltransferase 1, mitochondrial (EC 2.3.1.-) (Lipoate biosynthesis protein) (Lipoate-protein ligase) (Lipoyl ligase) |
Homo sapiens TI:9606 None |
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LIPT_MOUSE Ensembl» |
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Lipt1 | Lipoyltransferase 1, mitochondrial (EC 2.3.1.-) (Lipoate biosynthesis protein) (Lipoate-protein ligase) (Lipoyl ligase) |
Mus musculus TI:10090 None |
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A0A9J7KXM4_BRAFL CTD» |
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LOC118413261 | Lipoyltransferase 1, mitochondrial-like |
Branchiostoma floridae TI:7739 None |
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A0A9J7KY94_BRAFL CTD» |
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LOC118413260 | Lipoyltransferase 1, mitochondrial-like |
Branchiostoma floridae TI:7739 None |
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D6W6Q3_TRICA EnsemblMetazoa» |
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AUGUSTUS-3.0.2_04121 | Lipoyltransferase 1, mitochondrial-like Protein |
Tribolium castaneum TI:7070 None |
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LPLA_MYCGE EnsemblBacteria» |
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lplA | Probable lipoate-protein ligase A (Lipoate--protein ligase) (EC 6.3.1.20) |
Mycoplasma genitalium TI:2097 None |
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A0A1D8PQ09_CANAL EnsemblFungi» |
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CAALFM_C602900CA orf19.13012 | Putative lipoate-protein ligase A |
Candida albicans TI:5476 None |
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A7EEZ5_SCLS1 EnsemblFungi» |
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SS1G_03886 | Putative lipoate-protein ligase A |
Sclerotinia sclerotiorum TI:5180 None |
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B6JZX6_SCHJY EnsemblFungi» |
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SJAG_01164 | Putative lipoate-protein ligase A |
Schizosaccharomyces japonicus TI:4897 None |
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E3KBU8_PUCGT EnsemblFungi» |
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PGTG_08209 | Putative lipoate-protein ligase A |
Puccinia graminis TI:5297 None |
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F4P681_BATDJ EnsemblBacteria» |
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BATDEDRAFT_25988 | Putative lipoate-protein ligase A |
Batrachochytrium dendrobatidis TI:109871 None |
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Q4WJ76_ASPFU EnsemblFungi» |
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AFUA_1G06950 | Putative lipoate-protein ligase A |
Aspergillus fumigatus TI:746128 None |
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Q5B148_EMENI EnsemblFungi» |
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ANIA_05732 | Putative lipoate-protein ligase A |
Emericella nidulans TI:162425 None |
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Q5KMI3_CRYNJ EnsemblFungi» |
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CNB01600 | Putative lipoate-protein ligase A |
Cryptococcus neoformans TI:5207 None |
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Q6CD50_YARLI EnsemblFungi» |
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YALI0_C03762g | Putative lipoate-protein ligase A |
Yarrowia lipolytica TI:4952 None |
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Q752G7_ASHGO EnsemblFungi» |
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AGOS_AFR609C | Putative lipoate-protein ligase A |
Ashbya gossypii TI:33169 None |
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V5IQZ2_NEUCR EnsemblFungi» |
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NCU05421 | Putative lipoate-protein ligase A |
Neurospora crassa TI:5141 None |
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LPLA_SCHPO PomBase» |
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aim22 | Putative lipoate-protein ligase A (EC 6.3.1.20) |
Schizosaccharomyces pombe TI:4896 None |
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LPLA_YEAST SGD» |
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AIM22 | Putative lipoate-protein ligase A (EC 6.3.1.20) (Altered inheritance rate of mitochondria protein 22) |
Saccharomyces cerevisiae TI:4932 None |
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Q4QII0_LEIMA EnsemblProtists» |
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LMJF_07_1060 | Putative lipoyl ligase (EC 6.-.-.-) |
Leishmania major TI:5664 None |
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A0A1S4H8N0_ANOGA EnsemblMetazoa» |
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Uncharacterized protein |
Anopheles gambiae TI:7165 None |
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A0BZP9_PARTE EnsemblProtists» |
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GSPATT00005868001 | lipoate--protein ligase (EC 6.3.1.20) |
Paramecium tetraurelia TI:5888 None |
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A2FWB1_TRIV3 VEuPathDB» |
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TVAG_094820 | lipoate--protein ligase (EC 6.3.1.20) |
Trichomonas vaginalis TI:5722 None |
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A5HZP4_CLOBH Ensembl» |
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lplA1 | lipoate--protein ligase (EC 6.3.1.20) |
Clostridium botulinum TI:1491 None |
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A5I2A5_CLOBH Ensembl» |
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lplA2 | lipoate--protein ligase (EC 6.3.1.20) |
Clostridium botulinum TI:1491 None |
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B9TD57_RICCO EnsemblBacteria» |
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RCOM_1923930 | lipoate--protein ligase (EC 6.3.1.20) |
Ricinus communis TI:3988 None |
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F0ZIN5_DICPU EnsemblProtists» |
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DICPUDRAFT_151371 | lipoate--protein ligase (EC 6.3.1.20) |
Dictyostelium purpureum TI:5786 None |
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Q2FZN7_STAA8 EnsemblBacteria» |
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SAOUHSC_00963 | lipoate--protein ligase (EC 6.3.1.20) |
Staphylococcus aureus TI:1280 None |
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Q2G147_STAA8 EnsemblBacteria» |
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SAOUHSC_00308 | lipoate--protein ligase (EC 6.3.1.20) |
Staphylococcus aureus TI:1280 None |
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Q54KY1_DICDI dictyBase» |
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DDB_G0287107 | lipoate--protein ligase (EC 6.3.1.20) |
Dictyostelium discoideum TI:44689 None |
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Q81GU9_BACCR EnsemblBacteria» |
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BC_1086 | lipoate--protein ligase (EC 6.3.1.20) |
Bacillus cereus TI:1396 None |
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Q8DPR1_STRR6 EnsemblBacteria» |
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lplA | lipoate--protein ligase (EC 6.3.1.20) |
Streptococcus pneumoniae TI:1313 None |
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Q8Y8H3_LISMO EnsemblBacteria» |
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lmo0931 | lipoate--protein ligase (EC 6.3.1.20) |
Listeria monocytogenes TI:1639 None |
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Q8Y8X8_LISMO EnsemblBacteria» |
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lmo0764 | lipoate--protein ligase (EC 6.3.1.20) |
Listeria monocytogenes TI:1639 None |
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