Collated Gene Ontology terms

Biological process: lipoyltransferase activity(2011, 2012, 2016, 2023, 2024) lipoate-protein ligase activity(2008, 2011, 2013, 2014, 2016, 2021, 2024) ligase activity(2024) ATP binding(2024) acyltransferase activity(2024) transferase activity(2024) metal ion binding(2024) catalytic activity(2014) N-acyltransferase activity(2024)

Molecular function: protein lipoylation2011, 2014, 2016, 2024 lipid metabolic process2003, 2007 protein modification process2003 protein maturation2017 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021

Cellular component: cytoplasm2009, 2023, 2024 mitochondrion2009, 2013, 2014, 2020, 2024 cytosol2014, 2021 mitochondrial matrix2015

Phylogenetic distribution

Chordates: 19/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 13/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 3/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 1/8 
Bacteria: 12/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
LPLA_ECOLI
EnsemblBacteria»
4.2
lplA Lipoate-protein ligase A
(EC 6.3.1.20) (Lipoate--protein ligase)		 Escherichia coli
TI:562 None
 
LIPT_HUMAN
Ensembl»
3.7
LIPT1 Lipoyltransferase 1, mitochondrial (EC 2.3.1.-) (Lipoate
biosynthesis protein) (Lipoate-protein ligase) (Lipoyl ligase)		 Homo sapiens
TI:9606 None
 
LPLA_SCHPO
PomBase»
1.6
aim22 Putative lipoate-protein ligase A (EC 6.3.1.20) Schizosaccharomyces pombe
TI:4896 None
 
LPLA_YEAST
SGD»
1.0
AIM22 Putative lipoate-protein ligase A (EC 6.3.1.20)
(Altered inheritance rate of mitochondria protein 22)		 Saccharomyces cerevisiae
TI:4932 None
 
Q8SX78_DROME
FlyBase»
1.0
Lipt1 LD05679p (LD22815p) (Uncharacterized protein, isoform
A) (Uncharacterized protein, isoform B)		 Drosophila melanogaster
TI:7227 None
 
D3Z7Z4_RAT
RGD»
0.5
Lipt1 Lipoyltransferase 1 Rattus norvegicus
TI:10116 None
   
LIPT_MOUSE
Ensembl»
0.5
Lipt1 Lipoyltransferase 1, mitochondrial (EC 2.3.1.-) (Lipoate
biosynthesis protein) (Lipoate-protein ligase) (Lipoyl ligase)		 Mus musculus
TI:10090 None
 
O45303_CAEEL
WormBase»
0.5
lipt-1 BPL/LPL catalytic domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q08CP2_DANRE
ZFIN»
0.5
zgc:152851 Lipoyltransferase 1, mitochondrial
(EC 2.3.1.181) (Zgc:152851)		 Danio rerio
TI:7955 None
 
Q54KY1_DICDI
dictyBase»
0.5
DDB_G0287107 lipoate--protein ligase (EC 6.3.1.20) Dictyostelium discoideum
TI:44689 None
 
A0A1D8PQ09_CANAL
EnsemblFungi»
0.0
CAALFM_C602900CA orf19.13012 Putative lipoate-protein ligase A Candida albicans
TI:5476 None
 
A0A1L8HGT8_XENLA
Xenbase»
0.0
lipt1.L Lipoyltransferase 1 L homeolog isoform X1 Xenopus laevis
TI:8355 None
   
A0A1S4H8N0_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
A0A2I2U9H5_FELCA
Ensembl»
0.0
LIPT1 Lipoyltransferase 1 Felis catus
TI:9685 None
 
A0A6I8NHL2_ORNAN
Ensembl»
0.0
LIPT1 BPL/LPL catalytic domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7P367_STRPU
EnsemblMetazoa»
0.0
BPL/LPL catalytic domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3PAB4_CANLF
Ensembl»
0.0
LIPT1 Lipoyltransferase 1 Canis lupus
TI:9612 None
   
A0A8R1V2D9_PRIPA
EnsemblMetazoa»
0.0
WBGene00304332 BPL/LPL catalytic domain-containing protein Pristionchus pacificus
TI:54126 None
   
A0A8V0YTB2_CHICK
Ensembl»
0.0
LIPT1 Lipoyltransferase 1 Gallus gallus
TI:9031 None
   
A0A9J7KXM4_BRAFL
CTD»
0.0
LOC118413261 Lipoyltransferase 1, mitochondrial-like Branchiostoma floridae
TI:7739 None
   
A0A9J7KY94_BRAFL
CTD»
0.0
LOC118413260 Lipoyltransferase 1, mitochondrial-like Branchiostoma floridae
TI:7739 None
   
A0BZP9_PARTE
EnsemblProtists»
0.0
GSPATT00005868001 lipoate--protein ligase (EC 6.3.1.20) Paramecium tetraurelia
TI:5888 None
 
A2FWB1_TRIV3
VEuPathDB»
0.0
TVAG_094820 lipoate--protein ligase (EC 6.3.1.20) Trichomonas vaginalis
TI:5722 None
 
A5HZP4_CLOBH
Ensembl»
0.0
lplA1 lipoate--protein ligase (EC 6.3.1.20) Clostridium botulinum
TI:1491 None
 
A5I2A5_CLOBH
Ensembl»
0.0
lplA2 lipoate--protein ligase (EC 6.3.1.20) Clostridium botulinum
TI:1491 None
 
A7EEZ5_SCLS1
EnsemblFungi»
0.0
SS1G_03886 Putative lipoate-protein ligase A Sclerotinia sclerotiorum
TI:5180 None
 
A7RGY5_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g81677 BPL/LPL catalytic domain-containing protein Nematostella vectensis
TI:45351 None
 
B3RK56_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_51631 BPL/LPL catalytic domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B6JZX6_SCHJY
EnsemblFungi»
0.0
SJAG_01164 Putative lipoate-protein ligase A Schizosaccharomyces japonicus
TI:4897 None
 
B7Q697_IXOSC
EnsemblMetazoa»
0.0
8036505 Lipoate-protein ligase, putative Ixodes scapularis
TI:6945 None
 
B9TD57_RICCO
EnsemblBacteria»
0.0
RCOM_1923930 lipoate--protein ligase (EC 6.3.1.20) Ricinus communis
TI:3988 None
 
D6W6Q3_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_04121 Lipoyltransferase 1, mitochondrial-like Protein Tribolium castaneum
TI:7070 None
 
E3KBU8_PUCGT
EnsemblFungi»
0.0
PGTG_08209 Putative lipoate-protein ligase A Puccinia graminis
TI:5297 None
 
E9FUZ6_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_311204 BPL/LPL catalytic domain-containing protein Daphnia pulex
TI:6669 None
 
F0ZIN5_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_151371 lipoate--protein ligase (EC 6.3.1.20) Dictyostelium purpureum
TI:5786 None
 
F4P681_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_25988 Putative lipoate-protein ligase A Batrachochytrium dendrobatidis
TI:109871 None
 
F6RNJ0_XENTR
Xenbase»
0.0
lipt1 Lipoyltransferase 1 (Lipoyltransferase
1, mitochondrial isoform X1)		 Xenopus tropicalis
TI:8364 None
   
F6VMC6_CIOIN
Ensembl»
0.0
BPL/LPL catalytic domain-containing protein Ciona intestinalis
TI:7719 None
   
F7ARC0_MONDO
Ensembl»
0.0
LIPT1 Lipoyltransferase 1 Monodelphis domestica
TI:13616 None
   
G3S0M5_GORGO
Ensembl»
0.0
LIPT1 Lipoyltransferase 1 Gorilla gorilla
TI:9593 None
 
H2L7T5_ORYLA
Ensembl»
0.0
lipt1 Lipoyltransferase 1 Oryzias latipes
TI:8090 None
   
H2QIE7_PANTR
Ensembl»
0.0
LIPT1 Lipoyltransferase 1 Pan troglodytes
TI:9598 None
 
H9G4E9_ANOCA
Ensembl»
0.0
LIPT1 Lipoyltransferase 1 Anolis carolinensis
TI:28377 None
   
LIPLA_PLAF7
EnsemblProtists»
0.0
LipL1 Lipoate--protein ligase 1 (EC 6.3.1.20) Plasmodium falciparum
TI:5833 None
 
LIPT_BOVIN
Ensembl»
0.0
LIPT1 Lipoyltransferase 1, mitochondrial (EC 2.3.1.-) (Lipoate
biosynthesis protein) (Lipoate-protein ligase) (Lipoyl ligase)		 Bos taurus
TI:9913 None
 
LPLA_MYCGE
EnsemblBacteria»
0.0
lplA Probable lipoate-protein ligase A
(Lipoate--protein ligase) (EC 6.3.1.20)		 Mycoplasma genitalium
TI:2097 None
 
LPLA_SALTY
EnsemblBacteria»
0.0
lplA Lipoate-protein ligase A
(EC 6.3.1.20) (Lipoate--protein ligase)		 Salmonella typhimurium
TI:28901 None
 
LPLA_VIBCH
EnsemblBacteria»
0.0
lplA Lipoate-protein ligase A
(EC 6.3.1.20) (Lipoate--protein ligase)		 Vibrio cholerae
TI:666 None
 
LPLA_YERPE
EnsemblBacteria»
0.0
lplA Lipoate-protein ligase A
(EC 6.3.1.20) (Lipoate--protein ligase)		 Yersinia pestis
TI:632 None
 
LPLJ_BACSU
EnsemblBacteria»
0.0
lplJ Lipoate-protein ligase LplJ
(EC 6.3.1.20) (Lipoate--protein ligase)		 Bacillus subtilis
TI:1423 None
 
Q2FZN7_STAA8
EnsemblBacteria»
0.0
SAOUHSC_00963 lipoate--protein ligase (EC 6.3.1.20) Staphylococcus aureus
TI:1280 None
 
Q2G147_STAA8
EnsemblBacteria»
0.0
SAOUHSC_00308 lipoate--protein ligase (EC 6.3.1.20) Staphylococcus aureus
TI:1280 None
 
Q4QII0_LEIMA
EnsemblProtists»
0.0
LMJF_07_1060 Putative lipoyl ligase (EC 6.-.-.-) Leishmania major
TI:5664 None
 
Q4WJ76_ASPFU
EnsemblFungi»
0.0
AFUA_1G06950 Putative lipoate-protein ligase A Aspergillus fumigatus
TI:746128 None
 
Q57YG7_TRYB2
VEuPathDB»
0.0
Tb08.12O16.190 Lipoate-protein ligase, putative (EC 6.-.-.-) Trypanosoma brucei
TI:5691 None
 
Q5B148_EMENI
EnsemblFungi»
0.0
ANIA_05732 Putative lipoate-protein ligase A Emericella nidulans
TI:162425 None
 
Q5KMI3_CRYNJ
EnsemblFungi»
0.0
CNB01600 Putative lipoate-protein ligase A Cryptococcus neoformans
TI:5207 None
 
Q6CD50_YARLI
EnsemblFungi»
0.0
YALI0_C03762g Putative lipoate-protein ligase A Yarrowia lipolytica
TI:4952 None
 
Q752G7_ASHGO
EnsemblFungi»
0.0
AGOS_AFR609C Putative lipoate-protein ligase A Ashbya gossypii
TI:33169 None
 
Q81GU9_BACCR
EnsemblBacteria»
0.0
BC_1086 lipoate--protein ligase (EC 6.3.1.20) Bacillus cereus
TI:1396 None
 
Q8AB02_BACTN
EnsemblBacteria»
0.0
BT_0310 Lipoate-protein ligase A Bacteroides thetaiotaomicron
TI:818 None
 
Q8DPR1_STRR6
EnsemblBacteria»
0.0
lplA lipoate--protein ligase (EC 6.3.1.20) Streptococcus pneumoniae
TI:1313 None
 
Q8Y8H3_LISMO
EnsemblBacteria»
0.0
lmo0931 lipoate--protein ligase (EC 6.3.1.20) Listeria monocytogenes
TI:1639 None
 
Q8Y8X8_LISMO
EnsemblBacteria»
0.0
lmo0764 lipoate--protein ligase (EC 6.3.1.20) Listeria monocytogenes
TI:1639 None
 
Q97U65_SACS2
EnsemblBacteria»
0.0
lplA-1 Lipoate-protein ligase A (LplA-1) Saccharolobus solfataricus
TI:2287 None
 
T1FN43_HELRO
EnsemblMetazoa»
0.0
20210241 BPL/LPL catalytic domain-containing protein Helobdella robusta
TI:6412 None
 
V5IQZ2_NEUCR
EnsemblFungi»
0.0
NCU05421 Putative lipoate-protein ligase A Neurospora crassa
TI:5141 None
 
W5NML4_LEPOC
Ensembl»
0.0
Lipoyltransferase 1 Lepisosteus oculatus
TI:7918 None