Collated Gene Ontology terms

Biological process: oxidoreductase activity(2024) steroid dehydrogenase activity(2023) propionyl-CoA C2-trimethyltridecanoyltransferase activity(2024) propanoyl-CoA C-acyltransferase activity(2024) metal ion binding(2024) acyltransferase activity(2024) L-xylulose reductase (NADP+) activity(2024)

Molecular function: cholesterol homeostasis2024 terpene catabolic process2019 secondary metabolite biosynthetic process2024 response to iron ion2010

Cellular component: mitochondrion2009, 2020, 2024 peroxisome2012, 2013, 2024 cytosol2010, 2018 plasma membrane2010 peptidoglycan-based cell wall2012 membrane2014

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 5/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 3/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
Q7PTS9_ANOGA
EnsemblMetazoa»
0.0
1269060 AGAP012513-PA Anopheles gambiae
TI:7165 None
 
Q7PTS8_ANOGA
EnsemblMetazoa»
0.0
1269063 AGAP012514-PA Anopheles gambiae
TI:7165 None
 
A0DBS4_PARTE
EnsemblProtists»
0.0
GSPATT00022083001 GSPATT00039387001 Chromosome undetermined scaffold_440, whole genome shotgun sequence
(Chromosome undetermined scaffold_72, whole genome shotgun sequence)		 Paramecium tetraurelia
TI:5888 None 		 
 
A0DKB5_PARTE
EnsemblProtists»
0.0
GSPATT00017811001 Chromosome undetermined scaffold_54,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
 
A0A2A6BE05_PRIPA
EnsemblMetazoa»
0.0
WBGene00093698 Dehydrogenase Pristionchus pacificus
TI:54126 None 		 
 
A0A2A6CCX6_PRIPA
EnsemblMetazoa»
0.0
WBGene00281486 Dehydrogenase Pristionchus pacificus
TI:54126 None 		 
 
A0A2A6CJ02_PRIPA
EnsemblMetazoa»
0.0
WBGene00098067 Dehydrogenase Pristionchus pacificus
TI:54126 None 		 
 
A0A2A6CQG0_PRIPA
EnsemblMetazoa»
0.0
WBGene00279922 Dehydrogenase Pristionchus pacificus
TI:54126 None 		 
 
A0A2A6B6E9_PRIPA
EnsemblMetazoa»
0.0
WBGene00112157 Dhs-6 Pristionchus pacificus
TI:54126 None
 
Q9VB10_DROME
FlyBase»
0.5
Hsdl2 GH01709p Drosophila melanogaster
TI:7227 None
 
A0A1D5R7B8_MACMU
Ensembl»
0.0
HSDL2 Hydroxysteroid dehydrogenase like 2 Macaca mulatta
TI:9544 None
   
A0A3B3HBR4_ORYLA
Ensembl»
0.0
hsdl2 Hydroxysteroid dehydrogenase like 2 Oryzias latipes
TI:8090 None
   
A0A5G2R0Z8_PIG
Ensembl»
0.0
HSDL2 Hydroxysteroid dehydrogenase like 2 Sus scrofa
TI:9823 None
   
A0A8I3MXG8_CANLF
Ensembl»
0.0
HSDL2 Hydroxysteroid dehydrogenase like 2 Canis lupus
TI:9612 None
   
A0A8V0XTZ1_CHICK
Ensembl»
0.0
HSDL2 Hydroxysteroid dehydrogenase like 2 Gallus gallus
TI:9031 None
   
F6PQF9_HORSE
Ensembl»
0.0
HSDL2 Hydroxysteroid dehydrogenase like 2 Equus caballus
TI:9796 None
   
F6S838_ORNAN
Ensembl»
0.0
HSDL2 Hydroxysteroid dehydrogenase like 2 Ornithorhynchus anatinus
TI:9258 None
   
F7DLI8_MONDO
Ensembl»
0.0
HSDL2 Hydroxysteroid dehydrogenase like 2 Monodelphis domestica
TI:13616 None
   
G1KTT6_ANOCA
Ensembl»
0.0
HSDL2 Hydroxysteroid dehydrogenase like 2 Anolis carolinensis
TI:28377 None
   
G2HIK2_PANTR
Ensembl»
0.0
HSDL2 Hydroxysteroid dehydrogenase like 2
(Hydroxysteroid dehydrogenase-like protein 2)		 Pan troglodytes
TI:9598 None
 
G3QV49_GORGO
Ensembl»
0.0
HSDL2 Hydroxysteroid dehydrogenase like 2 Gorilla gorilla
TI:9593 None
 
M3WKK8_FELCA
Ensembl»
0.0
HSDL2 Hydroxysteroid dehydrogenase like 2 Felis catus
TI:9685 None
 
W5M4X2_LEPOC
Ensembl»
0.0
Hydroxysteroid dehydrogenase like 2 Lepisosteus oculatus
TI:7918 None
 
A0A9J7MBN5_BRAFL
CTD»
0.0
LOC118431278 Hydroxysteroid dehydrogenase-like protein
2 isoform X1		 Branchiostoma floridae
TI:7739 None
   
HSDL2_BOVIN
Ensembl»
0.0
HSDL2 Hydroxysteroid dehydrogenase-like protein
2 (EC 1.-.-.-)		 Bos taurus
TI:9913 None
 
HSDL2_DANRE
ZFIN»
0.0
hsdl2 Hydroxysteroid dehydrogenase-like protein
2 (EC 1.-.-.-)		 Danio rerio
TI:7955 None
 
HSDL2_MOUSE
Ensembl»
0.8
Hsdl2 Hydroxysteroid dehydrogenase-like protein
2 (EC 1.-.-.-)		 Mus musculus
TI:10090 None
 
HSDL2_RAT
RGD»
0.5
Hsdl2 Hydroxysteroid dehydrogenase-like protein
2 (EC 1.-.-.-)		 Rattus norvegicus
TI:10116 None
 
HSDL2_XENLA
AG»
0.0
hsdl2 Hydroxysteroid dehydrogenase-like protein
2 (EC 1.-.-.-)		 Xenopus laevis
TI:8355 None
 
HSDL2_XENTR
CTD»
0.0
hsdl2 Hydroxysteroid dehydrogenase-like protein
2 (EC 1.-.-.-)		 Xenopus tropicalis
TI:8364 None
 
A0A9J7LE91_BRAFL
CTD»
0.0
LOC118418524 Hydroxysteroid dehydrogenase-like protein 2 Branchiostoma floridae
TI:7739 None
   
A0A9J7MCX4_BRAFL
CTD»
0.0
LOC118431296 Hydroxysteroid dehydrogenase-like protein 2 Branchiostoma floridae
TI:7739 None 		     
A0A9J7NC55_BRAFL
CTD»
0.0
LOC118431290 Hydroxysteroid dehydrogenase-like protein 2 Branchiostoma floridae
TI:7739 None 		     
A7TCZ7_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g225442 Hydroxysteroid dehydrogenase-like protein 2 Nematostella vectensis
TI:45351 None
 
B3S3Y5_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_58889 Hydroxysteroid dehydrogenase-like protein 2 Trichoplax adhaerens
TI:10228 None
 
D6WW74_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_05801 Hydroxysteroid dehydrogenase-like protein 2 Tribolium castaneum
TI:7070 None
 
E9FUQ6_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_311120 Hydroxysteroid dehydrogenase-like protein 2 Daphnia pulex
TI:6669 None
 
F6ZPV8_CIOIN
Ensembl»
0.0
LOC100181032 Hydroxysteroid dehydrogenase-like protein 2 Ciona intestinalis
TI:7719 None
 
Q18639_CAEEL
WormBase»
0.0
dhs-18 Hydroxysteroid dehydrogenase-like protein 2 Caenorhabditis elegans
TI:6239 None
 
Q54DN0_DICDI
dictyBase»
0.0
DDB_G0292116 Hydroxysteroid dehydrogenase-like protein 2 Dictyostelium discoideum
TI:44689 None 		 
 
HSDL2_HUMAN
Ensembl»
1.6
HSDL2 Hydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-)
(Short chain dehydrogenase/reductase family 13C member 1)		 Homo sapiens
TI:9606 None
 
O05842_MYCTU
TubercuList»
0.0
Rv3224 Possible iron-regulated
short-chain dehydrogenase/reductase		 Mycobacterium tuberculosis
TI:1773 None
 
A8X420_CAEBR
WormBase»
0.0
CBG06958 CBG_06958 Protein CBG06958 Caenorhabditis briggsae
TI:6238 None
 
A8Y4Q0_CAEBR
WormBase»
0.0
dhs-18 Protein CBR-DHS-18 Caenorhabditis briggsae
TI:6238 None
 
A8X421_CAEBR
WormBase»
0.0
dhs-6 Protein CBR-DHS-6 Caenorhabditis briggsae
TI:6238 None
 
A0A5F8GDI1_MONDO
Ensembl»
0.0
SCP2 domain-containing protein Monodelphis domestica
TI:13616 None
   
A0A7M7PHX0_STRPU
EnsemblMetazoa»
0.0
SCP2 domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7T419_STRPU
EnsemblMetazoa»
0.0
SCP2 domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A7S138_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g184356 SCP2 domain-containing protein Nematostella vectensis
TI:45351 None
 
E9HNJ1_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_203975 SCP2 domain-containing protein Daphnia pulex
TI:6669 None
 
Q09979_CAEEL
WormBase»
0.0
dhs-6 SCP2 domain-containing protein Caenorhabditis elegans
TI:6239 None
 
T1FN73_HELRO
EnsemblMetazoa»
0.0
20210271 SCP2 domain-containing protein Helobdella robusta
TI:6412 None
 
A7F4W6_SCLS1
EnsemblFungi»
0.0
SS1G_12641 Short chain dehydrogenase Sclerotinia sclerotiorum
TI:5180 None 		 
 
A9V2J8_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_32924 Short chain dehydrogenase Monosiga brevicollis
TI:81824 None
 
F0Z9Y1_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_52772 Short chain dehydrogenase Dictyostelium purpureum
TI:5786 None 		 
 
F4NXA4_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_9328 Short chain dehydrogenase Batrachochytrium dendrobatidis
TI:109871 None
 
Q4WRE0_ASPFU
EnsemblFungi»
0.0
AFUA_1G16630 Short chain dehydrogenase
family protein (EC 1.-.-.-)		 Aspergillus fumigatus
TI:746128 None
 
Q7RZQ9_NEUCR
EnsemblFungi»
0.0
NCU00305 Short chain dehydrogenase Neurospora crassa
TI:5141 None
 
Q8P5Q1_XANCP
EnsemblBacteria»
0.0
XCC3285 Short chain dehydrogenase Xanthomonas campestris
TI:339 None
 
Q9HZV5_PSEAE
EnsemblBacteria»
0.0
atuG Short chain dehydrogenase involved
in catabolism of citronellol		 Pseudomonas aeruginosa
TI:287 None
 
B7PKM5_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW018577 Short-chain dehydrogenase, putative (EC 1.1.1.10,
EC 2.3.1.176) (Short-chain dehydrogenase, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
E9GYY1_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_108031 Uncharacterized protein Daphnia pulex
TI:6669 None