Collated Gene Ontology terms

Biological process: 6,7-dihydropteridine reductase activity(2003, 2008, 2010, 2011, 2019, 2020, 2022, 2024) oxidoreductase activity(2024) NADPH binding(2011, 2017, 2024) NADH binding(2011, 2017, 2024) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(2024) identical protein binding(2011, 2019, 2024) NAD binding(2019, 2024) electron transfer activity(2006)

Molecular function: tetrahydrobiopterin biosynthetic process2005, 2008, 2010, 2011, 2013, 2017, 2024 L-phenylalanine catabolic process2011, 2017, 2024 response to oxidative stress2013, 2024 melanin biosynthetic process2020, 2024 L-phenylalanine metabolic process2020, 2024 response to lead ion2011 response to glucagon2011 response to aluminum ion2011 liver development2011 glutamine metabolic process2020
gliogenesis2020 dihydrobiopterin metabolic process2004 cellular response to xenobiotic stimulus2011 brain development2020 amino acid metabolic process2003

Cellular component: cytoplasm2010, 2023, 2024 mitochondrion2009, 2024 phagocytic vesicle2009 extracellular exosome2014 cytosol2013

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 5 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q9XVJ3_CAEEL
WormBase»
2.5
qdpr-1 Dihydropteridine reductase dhpr/qdpr Caenorhabditis elegans
TI:6239 None
 
A0A8M3B0J5_DANRE
CTD»
2.5
qdprb2 Quinoid dihydropteridine reductase b2 isoform X2 Danio rerio
TI:7955 None
   
A7YT77_DANRE
ZFIN»
4.1
si:ch211-89f22.2 Qdpra protein (Quinoid
dihydropteridine reductase a)		 Danio rerio
TI:7955 None
 
A8KB38_DANRE
ZFIN»
2.5
qdprb.4 Uncharacterized protein LOC563255
precursor (Zgc:171517 protein)		 Danio rerio
TI:7955 None
 
Q66IB5_DANRE
ZFIN»
5.7
qdprb1 Dihydropteridine reductase (EC 1.5.1.34) (Qdprb1
protein) (Quinoid dihydropteridine reductase b1)		 Danio rerio
TI:7955 None
 
DHPR_DICDI
dictyBase»
7.5
qdpr Dihydropteridine reductase (EC
1.5.1.34) (Quinoid dihydropteridine reductase)		 Dictyostelium discoideum
TI:44689 None
 
Q9VSU6_DROME
FlyBase»
2.5
Dhpr Dihydropteridine reductase (Dihydropteridine reductase, isoform A (EC 1.5.1.34))
(Dihydropteridine reductase, isoform B) (Dihydropteridine reductase, isoform C) (RE58329p)		 Drosophila melanogaster
TI:7227 None
 
A0A8V0Y9C4_CHICK
Ensembl»
0.0
QDPR Quinoid dihydropteridine reductase Gallus gallus
TI:9031 None
   
DHPR_HUMAN
Ensembl»
6.9
QDPR Dihydropteridine reductase (EC 1.5.1.34) (HDHPR) (Quinoid dihydropteridine
reductase) (Short chain dehydrogenase/reductase family 33C member 1)		 Homo sapiens
TI:9606 None
 
DHPR_MOUSE
Ensembl»
1.0
Qdpr Dihydropteridine reductase (EC 1.5.1.34)
(HDHPR) (Quinoid dihydropteridine reductase)		 Mus musculus
TI:10090 None
 
A0A8I6G9Y8_RAT
RGD»
0.0
AABR07068905.1 Uncharacterized protein Rattus norvegicus
TI:10116 None
   
DHPR_RAT
RGD»
14.3
Qdpr Dihydropteridine reductase (EC 1.5.1.34)
(HDHPR) (Quinoid dihydropteridine reductase)		 Rattus norvegicus
TI:10116 None