Collated Gene Ontology terms

Biological process: translation elongation factor activity(2024) RNA binding(2004, 2024)

Molecular function: negative regulation of transcription elongation by RNA polymerase II2011, 2018, 2022, 2024 negative regulation of DNA-templated transcription2024 stem cell differentiation2018, 2024 negative regulation of stem cell differentiation2018, 2024 cell population proliferation2018, 2024 translational elongation2024 regulation of granulocyte differentiation2023 negative regulation of transcription by RNA polymerase II2013, 2018 positive regulation of transcription by RNA polymerase II2013 positive regulation of hematopoietic stem cell differentiation2017
positive regulation of hematopoietic progenitor cell differentiation2017

Cellular component: NELF complex2011, 2012, 2017, 2022, 2024 nucleus2011, 2022, 2024 nucleoplasm2013, 2023, 2024 cytoplasm2010, 2024 transcription repressor complex2004 mitochondrial outer membrane2018 cytosol2018 chromosome2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 1/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 0/35 

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Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

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Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
NELFB_DROME
FlyBase»
3.9
NELF-B Negative elongation factor B Drosophila melanogaster
TI:7227 None
 
Q7ZVU3_DANRE
ZFIN»
3.7
cobra1 Cobra1 protein (Cofactor of
BRCA1) (Negative elongation factor B)		 Danio rerio
TI:7955 None
 
NELFB_HUMAN
Ensembl»
3.3
NELFB Negative elongation factor B
(NELF-B) (Cofactor of BRCA1)		 Homo sapiens
TI:9606 None
 
NELFB_MOUSE
Ensembl»
3.2
Nelfb Negative elongation factor B
(NELF-B) (Cofactor of BRCA1)		 Mus musculus
TI:10090 None
 
D4ACV0_RAT
RGD»
2.5
Nelfb Negative elongation factor complex member B Rattus norvegicus
TI:10116 None
   
Q54Q08_DICDI
dictyBase»
0.5
DDB_G0284195 Negative elongation factor B Dictyostelium discoideum
TI:44689 None
 
Q5ZLK9_CHICK
Ensembl»
0.5
NELFB Negative elongation factor complex member B Gallus gallus
TI:9031 None