Collated Gene Ontology terms

Biological process: translation elongation factor activity(2024) RNA binding(2004, 2024)

Molecular function: negative regulation of transcription elongation by RNA polymerase II2011, 2018, 2022, 2024 negative regulation of DNA-templated transcription2024 stem cell differentiation2018, 2024 negative regulation of stem cell differentiation2018, 2024 cell population proliferation2018, 2024 translational elongation2024 regulation of granulocyte differentiation2023 negative regulation of transcription by RNA polymerase II2013, 2018 positive regulation of transcription by RNA polymerase II2013 positive regulation of hematopoietic stem cell differentiation2017
positive regulation of hematopoietic progenitor cell differentiation2017

Cellular component: NELF complex2011, 2012, 2017, 2022, 2024 nucleus2011, 2022, 2024 nucleoplasm2013, 2023, 2024 cytoplasm2010, 2024 transcription repressor complex2004 mitochondrial outer membrane2018 cytosol2018 chromosome2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 1/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
H9GIZ5_ANOCA
Ensembl»
0.0
nelfb Negative elongation factor complex member B Anolis carolinensis
TI:28377 None
   
A0A1S4H8C8_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
G5E5S2_BOVIN
Ensembl»
0.0
NELFB Negative elongation factor complex member B Bos taurus
TI:9913 None
   
C3Y2N3_BRAFL
CTD»
0.0
LOC118421406 Negative elongation factor B-like Branchiostoma floridae
TI:7739 None
 
A0A8I3S3F0_CANLF
Ensembl»
0.0
NELFB Uncharacterized protein Canis lupus
TI:9612 None
   
A0A2K3CX59_CHLRE
EnsemblPlants»
0.0
CHLRE_14g610050v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None
 
F6XUA1_CIOIN
Ensembl»
0.0
LOC100186426 Negative elongation factor B Ciona intestinalis
TI:7719 None
   
Q7ZVU3_DANRE
ZFIN»
3.7
cobra1 Cobra1 protein (Cofactor of
BRCA1) (Negative elongation factor B)		 Danio rerio
TI:7955 None
 
E9FUT5_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_206529 Negative elongation factor B Daphnia pulex
TI:6669 None
 
F0Z8H3_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_52489 Negative elongation factor B Dictyostelium purpureum
TI:5786 None
 
Q54Q08_DICDI
dictyBase»
0.5
DDB_G0284195 Negative elongation factor B Dictyostelium discoideum
TI:44689 None
 
NELFB_DROME
FlyBase»
3.9
NELF-B Negative elongation factor B Drosophila melanogaster
TI:7227 None
 
A0A3Q2HFS7_HORSE
Ensembl»
0.0
NELFB Negative elongation factor complex member B Equus caballus
TI:9796 None
   
A0A2I2UAF2_FELCA
Ensembl»
0.0
NELFB Negative elongation factor complex member B Felis catus
TI:9685 None
 
Q5ZLK9_CHICK
Ensembl»
0.5
NELFB Negative elongation factor complex member B Gallus gallus
TI:9031 None
 
G3QHN2_GORGO
Ensembl»
0.0
NELFB Negative elongation factor complex member B Gorilla gorilla
TI:9593 None
 
T1FUY8_HELRO
EnsemblMetazoa»
0.0
20212634 Negative elongation factor B Helobdella robusta
TI:6412 None
 
NELFB_HUMAN
Ensembl»
3.3
NELFB Negative elongation factor B
(NELF-B) (Cofactor of BRCA1)		 Homo sapiens
TI:9606 None
 
W5M0U2_LEPOC
Ensembl»
0.0
Negative elongation factor complex member B Lepisosteus oculatus
TI:7918 None
 
H9FSL9_MACMU
Ensembl»
0.0
NELFB Negative elongation factor B (Negative
elongation factor complex member B)		 Macaca mulatta
TI:9544 None
 
F6WYC3_MONDO
Ensembl»
0.0
NELFB Negative elongation factor complex member B Monodelphis domestica
TI:13616 None
   
A9UT03_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_31409 Uncharacterized protein Monosiga brevicollis
TI:81824 None
 
NELFB_MOUSE
Ensembl»
3.2
Nelfb Negative elongation factor B
(NELF-B) (Cofactor of BRCA1)		 Mus musculus
TI:10090 None
 
A7T0W2_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g195244 Negative elongation factor B Nematostella vectensis
TI:45351 None
 
F7AIV3_ORNAN
Ensembl»
0.0
NELFB Negative elongation factor complex member B Ornithorhynchus anatinus
TI:9258 None
   
H2MIY2_ORYLA
Ensembl»
0.0
nelfb Negative elongation factor complex member B Oryzias latipes
TI:8090 None
   
H2R3L1_PANTR
Ensembl»
0.0
NELFB Negative elongation factor complex member B Pan troglodytes
TI:9598 None
 
H3GUF8_PHYRM
EnsemblProtists»
0.0
Bromo domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3HAK6_PHYRM
EnsemblProtists»
0.0
Bromo domain-containing protein Phytophthora ramorum
TI:164328 None
 
A0A2A6C5C1_PRIPA
EnsemblMetazoa»
0.0
WBGene00272935 Cofactor of BRCA1 Pristionchus pacificus
TI:54126 None
 
D4ACV0_RAT
RGD»
2.5
Nelfb Negative elongation factor complex member B Rattus norvegicus
TI:10116 None
   
A0A7M7RA91_STRPU
EnsemblMetazoa»
0.0
Negative elongation factor B Strongylocentrotus purpuratus
TI:7668 None
   
A0A287BM68_PIG
Ensembl»
0.0
NELFB Negative elongation factor complex member B Sus scrofa
TI:9823 None
   
D6WGY9_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_03481 Negative elongation factor B-like Protein Tribolium castaneum
TI:7070 None
 
B3RNG6_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_13686 Negative elongation factor B Trichoplax adhaerens
TI:10228 None
 
Q32NK8_XENLA
Xenbase»
0.0
nelfb.L MGC131073 protein (Negative elongation factor
complex member B L homeolog)		 Xenopus laevis
TI:8355 None
 
Q5I0A8_XENTR
Xenbase»
0.0
nelfb Hypothetical LOC496936 (Negative
elongation factor B)		 Xenopus tropicalis
TI:8364 None