Biological process: TRAIL binding^{(2002, 2003, 2005, 2024)} protease binding^{(2014, 2024)} identical protein binding^{(2020, 2024)} transmembrane signaling receptor activity^{(2003, 2005, 2024)} signaling receptor activity⁽²⁰²⁴⁾ TRAIL receptor activity^{(2020, 2024)} transferase activity⁽²⁰²⁴⁾ nucleotide binding⁽²⁰²⁴⁾ death receptor activity⁽²⁰⁰³⁾ cysteine-type endopeptidase activator activity involved in apoptotic process⁽²⁰⁰⁵⁾
± 2 carbohydrate binding²⁰²⁴ calmodulin binding²⁰²⁴

Molecular function: TRAIL-activated apoptotic signaling pathway^{2014, 2018, 2020, 2024} apoptotic process^{2002, 2004, 2005, 2024} signal transduction^{2003, 2005, 2024} positive regulation of apoptotic process^{2007, 2020} regulation of apoptotic process^{2004, 2005, 2024} cellular response to mechanical stimulus^{2011, 2024} extrinsic apoptotic signaling pathway^{2011, 2024} intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress^{2012, 2015, 2024} extrinsic apoptotic signaling pathway via death domain receptors^{2002, 2003, 2010} response to endoplasmic reticulum stress^{2012, 2024}
± 10 positive regulation of I-kappaB kinase/NF-kappaB signaling^{2004, 2024} negative regulation of extrinsic apoptotic signaling pathway via death domain receptors²⁰¹³ defense response to tumor cell^{2021, 2024} activation of NF-kappaB-inducing kinase activity²⁰⁰⁴ polysaccharide catabolic process²⁰²⁴ negative regulation of multicellular organismal process²⁰²⁴ negative regulation of apoptotic process²⁰⁰⁵ male gonad development²⁰⁰⁸ immune response²⁰²⁴ cell surface receptor signaling pathway²⁰⁰⁵

Cellular component: plasma membrane^{2013, 2014, 2016, 2018, 2020, 2024} membrane²⁰²⁴ cell surface^{2015, 2018, 2024} membrane raft^{2020, 2024} cytosol^{2020, 2024} Golgi apparatus^{2020, 2024} plasma membrane raft²⁰²⁴ external side of plasma membrane²⁰¹³ side of membrane²⁰²⁴ extracellular region²⁰²⁴
± 1 cytoplasm²⁰²⁴