Collated Gene Ontology terms

Biological process: TRAIL binding(2002, 2003, 2005, 2024) protease binding(2014, 2024) identical protein binding(2020, 2024) transmembrane signaling receptor activity(2003, 2005, 2024) signaling receptor activity(2024) TRAIL receptor activity(2020, 2024) transferase activity(2024) nucleotide binding(2024) death receptor activity(2003) cysteine-type endopeptidase activator activity involved in apoptotic process(2005)
carbohydrate binding2024 calmodulin binding2024

Molecular function: TRAIL-activated apoptotic signaling pathway2014, 2018, 2020, 2024 apoptotic process2002, 2004, 2005, 2024 signal transduction2003, 2005, 2024 positive regulation of apoptotic process2007, 2020 regulation of apoptotic process2004, 2005, 2024 cellular response to mechanical stimulus2011, 2024 extrinsic apoptotic signaling pathway2011, 2024 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress2012, 2015, 2024 extrinsic apoptotic signaling pathway via death domain receptors2002, 2003, 2010 response to endoplasmic reticulum stress2012, 2024
positive regulation of I-kappaB kinase/NF-kappaB signaling2004, 2024 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors2013 defense response to tumor cell2021, 2024 activation of NF-kappaB-inducing kinase activity2004 polysaccharide catabolic process2024 negative regulation of multicellular organismal process2024 negative regulation of apoptotic process2005 male gonad development2008 immune response2024 cell surface receptor signaling pathway2005

Cellular component: plasma membrane2013, 2014, 2016, 2018, 2020, 2024 membrane2024 cell surface2015, 2018, 2024 membrane raft2020, 2024 cytosol2020, 2024 Golgi apparatus2020, 2024 plasma membrane raft2024 external side of plasma membrane2013 side of membrane2024 extracellular region2024
cytoplasm2024

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 0/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 0/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A0G2JZE1_RAT
RGD»
5.1
Tnfrsf10b TNF receptor superfamily member 10b Rattus norvegicus
TI:10116 None
   
A0A1D5QF90_MACMU
Ensembl»
0.0
TNFRSF10B TNF receptor superfamily member 10b Macaca mulatta
TI:9544 None
   
A0A286ZQG3_PIG
Ensembl»
0.0
LOC100624226 Tumor necrosis factor
receptor superfamily member 10A		 Sus scrofa
TI:9823 None
 
A0A2I2Z0T3_GORGO
Ensembl»
0.0
TNFRSF10B TNF receptor superfamily member 10b Gorilla gorilla
TI:9593 None
 
A0A2I2ZI00_GORGO
Ensembl»
0.0
TNFRSF10A TNF receptor superfamily member 10a Gorilla gorilla
TI:9593 None
 
A0A2I2ZU78_GORGO
Ensembl»
0.0
TNF receptor superfamily member 10c Gorilla gorilla
TI:9593 None
 
A0A2I3RUZ2_PANTR
Ensembl»
0.0
TNFRSF10A TNF receptor superfamily member 10a (Tumor
necrosis factor receptor superfamily, member 10a)		 Pan troglodytes
TI:9598 None
 
A0A2K3DK38_CHLRE
EnsemblPlants»
0.0
CHLRE_07g334150v5 TNFR-Cys domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A3B3HLQ6_ORYLA
Ensembl»
0.0
LOC101172833 Tumor necrosis factor
receptor superfamily member 10B		 Oryzias latipes
TI:8090 None
   
A0A3B3IN84_ORYLA
Ensembl»
0.0
LOC101173230 Tumor necrosis factor
receptor superfamily member 22		 Oryzias latipes
TI:8090 None
   
A0A3Q1MGT5_BOVIN
Ensembl»
0.0
LOC104968444 TNFR-Cys domain-containing protein Bos taurus
TI:9913 None
   
A0A3Q1N250_BOVIN
Ensembl»
0.0
TNFRSF10D Tumor necrosis factor receptor superfamily, member
10d, decoy with truncated death domain		 Bos taurus
TI:9913 None
   
A0A5F5XH25_FELCA
Ensembl»
0.0
Tumor necrosis factor
receptor superfamily member 1A		 Felis catus
TI:9685 None
 
A0A5F8AL04_MACMU
Ensembl»
0.0
Uncharacterized protein Macaca mulatta
TI:9544 None 		       
A0A6I8NUM1_ORNAN
Ensembl»
0.0
LOC103169510 Uncharacterized protein Ornithorhynchus anatinus
TI:9258 None
   
A0A8I3NIL9_CANLF
Ensembl»
0.0
LOC100688321 Uncharacterized protein Canis lupus
TI:9612 None
   
A0A8I5ZU03_RAT
RGD»
1.0
Tnfrsf22 Tumor necrosis factor
receptor superfamily, member 22		 Rattus norvegicus
TI:10116 None
   
A0A8I6A0F5_RAT
RGD»
0.0
Tnfrsf26 Tumor necrosis factor
receptor superfamily, member 26		 Rattus norvegicus
TI:10116 None
   
A0A8J0T281_XENTR
Xenbase»
0.0
tnfrsf10b Tumor necrosis factor receptor
superfamily member 10A isoform X1		 Xenopus tropicalis
TI:8364 None
   
A0A8M1P718_DANRE
CTD»
1.8
tnfrsfa Tumor necrosis factor receptor
superfamily, member a precursor		 Danio rerio
TI:7955 None
   
A0A8V0ZHP3_CHICK
Ensembl»
0.0
TNFRSF10B Tumor necrosis factor
receptor superfamily, member 10b		 Gallus gallus
TI:9031 None
   
A0A8V0ZQD1_CHICK
Ensembl»
0.0
LOC378902 Tumor necrosis factor receptor superfamily member 6
(Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor)		 Gallus gallus
TI:9031 None
   
A0A9J7LGY3_BRAFL
CTD»
0.0
LOC118420058 Tumor necrosis factor
receptor superfamily member 1B-like		 Branchiostoma floridae
TI:7739 None
   
A9UU81_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_23706 TNFR-Cys domain-containing protein Monosiga brevicollis
TI:81824 None
 
A9UZL9_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_8292 TNFR-Cys domain-containing protein Monosiga brevicollis
TI:81824 None
 
A9V610_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_27688 Apple domain-containing protein Monosiga brevicollis
TI:81824 None
 
A9V9B5_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_34072 TNFR-Cys domain-containing protein Monosiga brevicollis
TI:81824 None
 
F1QD95_DANRE
ZFIN»
1.8
ZH-DR Hematopoietic death receptor (Hematopoietic
death receptor isoform X1)		 Danio rerio
TI:7955 None
 
F6R5A9_BOVIN
Ensembl»
0.0
LOC510798 TNFR-Cys domain-containing protein Bos taurus
TI:9913 None
   
F6SDD8_HORSE
Ensembl»
0.0
TNFRSF10B TNF receptor superfamily member 10a Equus caballus
TI:9796 None
   
F6SDY4_HORSE
Ensembl»
0.0
TNFR-Cys domain-containing protein Equus caballus
TI:9796 None
   
F6TP00_MACMU
Ensembl»
0.0
TNFRSF10A TNF receptor superfamily member 10a Macaca mulatta
TI:9544 None
   
F7EED4_MONDO
Ensembl»
0.0
LOC103100524 Tumor necrosis factor
receptor superfamily member 10A		 Monodelphis domestica
TI:13616 None
   
G3MZC6_BOVIN
Ensembl»
0.0
TNFRSF10D Tumor necrosis factor receptor superfamily, member
10d, decoy with truncated death domain		 Bos taurus
TI:9913 None
   
G3QYB0_GORGO
Ensembl»
0.0
TNFRSF10D TNF receptor superfamily member 10d Gorilla gorilla
TI:9593 None
 
H2QVV8_PANTR
Ensembl»
0.0
TNFRSF10B TNF receptor superfamily member 10b Pan troglodytes
TI:9598 None
 
H2QVV9_PANTR
Ensembl»
0.0
TNFRSF10C TNF receptor superfamily member 10c Pan troglodytes
TI:9598 None
 
H2QVW0_PANTR
Ensembl»
0.0
TNFRSF10D TNF receptor superfamily member 10d Pan troglodytes
TI:9598 None
 
H9GNG4_ANOCA
Ensembl»
0.0
Death domain-containing protein Anolis carolinensis
TI:28377 None
   
I3L5L0_PIG
Ensembl»
0.0
LOC100737977 Tumor necrosis factor
receptor superfamily member 10A		 Sus scrofa
TI:9823 None
   
TNR22_MOUSE
Ensembl»
1.6
Tnfrsf22 Tumor necrosis factor receptor superfamily member 22 (Decoy TRAIL receptor 2) (TNF receptor
family member SOBa) (TNF receptor homolog 2) (Tumor necrosis factor receptor p60 homolog 2)		 Mus musculus
TI:10090 None
 
TNR26_MOUSE
Ensembl»
0.0
Tnfrsf26 Tumor necrosis factor receptor superfamily
member 26 (TNF receptor homolog 3)		 Mus musculus
TI:10090 None
 
TR10A_HUMAN
Ensembl»
11.5
TNFRSF10A Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related
apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261)		 Homo sapiens
TI:9606 None
 
TR10B_HUMAN
Ensembl»
12.0
TNFRSF10B Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related
apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262)		 Homo sapiens
TI:9606 None
 
TR10B_MOUSE
Ensembl»
3.4
Tnfrsf10b Tumor necrosis factor receptor superfamily member 10B
(Death receptor 5) (MK) (CD antigen CD262)		 Mus musculus
TI:10090 None
 
TR10C_HUMAN
Ensembl»
1.9
TNFRSF10C Tumor necrosis factor receptor superfamily member 10C (Antagonist decoy receptor for TRAIL/Apo-2L) (Decoy TRAIL receptor without death domain) (Decoy receptor 1) (DcR1)
(Lymphocyte inhibitor of TRAIL) (TNF-related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (TRAIL receptor without an intracellular domain) (CD antigen CD263)		 Homo sapiens
TI:9606 None
 
TR10D_HUMAN
Ensembl»
2.7
TNFRSF10D Tumor necrosis factor receptor superfamily member 10D (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor
4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD antigen CD264)		 Homo sapiens
TI:9606 None
 
W5NEG9_LEPOC
Ensembl»
0.0
Tumor necrosis factor
receptor superfamily member 10A-like		 Lepisosteus oculatus
TI:7918 None