Collated Gene Ontology terms

Biological process: nuclease activity(2008, 2025) single-stranded DNA endodeoxyribonuclease activity(2024, 2025) 3' overhang single-stranded DNA endodeoxyribonuclease activity(2024, 2025) DNA endonuclease activity(2025) hydrolase activity(2025) endonuclease activity(2025)

Molecular function: double-strand break repair via nonhomologous end joining2024, 2025 double-strand break repair via homologous recombination2024, 2025 DNA recombination2025 larval somatic muscle development2006 imaginal disc-derived wing vein morphogenesis2006 imaginal disc-derived wing morphogenesis2007 compound eye photoreceptor fate commitment2007 compound eye morphogenesis2006 DNA repair2017 DNA metabolic process2025

Cellular component: site of double-strand break2013 nucleus2017 mitochondrion2025 cytoplasm2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 6/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 2/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A1L8FWH2_XENLA
Xenbase»
0.0
aste1.L Protein asteroid homolog 1 isoform X1 Xenopus laevis
TI:8355 None 		     
B2GUH0_XENTR
Xenbase»
0.0
aste1 LOC100158587 protein (Protein
asteroid homolog 1)		 Xenopus tropicalis
TI:8364 None 		 
 
B3S096_TRIAD
CTD»
0.0
TRIADDRAFT_57734 Uncharacterized protein Trichoplax adhaerens
TI:10228 None 		 
 
A2EM86_TRIV3
TubercuList»
0.0
TVAG_470410 Asteroid domain-containing protein Trichomonas vaginalis
TI:5722 None 		 
 
A2EN66_TRIV3
TubercuList»
0.0
TVAG_353440 XPG N-terminal domain-containing protein Trichomonas vaginalis
TI:5722 None 		 
 
A2F0V9_TRIV3
TubercuList»
0.0
TVAG_490220 XPG N-terminal domain containing protein Trichomonas vaginalis
TI:5722 None 		 
 
A2FYA9_TRIV3
TubercuList»
0.0
TVAG_256150 XPG N-terminal domain containing protein Trichomonas vaginalis
TI:5722 None 		 
 
D6WJ78_TRICA
CTD»
0.0
AUGUSTUS-3.0.2_14736 Protein asteroid homolog 1-like Protein Tribolium castaneum
TI:7070 None
 
F1RSA3_PIG
Ensembl»
0.0
ASTE1 Asteroid homolog 1 Sus scrofa
TI:9823 None
   
A0A7M7N5K1_STRPU
EnsemblMetazoa»
0.0
XPG N-terminal domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
AST1_SCHPO
PomBase»
1.0
ast1 Asteroid homolog 1 Schizosaccharomyces pombe
TI:4896 None
 
B6JV48_SCHJY
TubercuList»
0.0
ast1 Asteroid Schizosaccharomyces japonicus
TI:4897 None 		 
 
A0A0G2K873_RAT
RGD»
2.0
Aste1 Asteroid homolog 1 Rattus norvegicus
TI:10116 None
   
A0A7U2EWU5_PHANO
TubercuList»
0.0
JI435_084360 Asteroid domain-containing protein Phaeosphaeria nodorum
TI:13684 None 		 
 
H2QND6_PANTR
Ensembl»
0.0
ASTE1 Asteroid homolog 1 Pan troglodytes
TI:9598 None
 
H2LFG5_ORYLA
Ensembl»
0.0
aste1b Asteroid domain-containing protein Oryzias latipes
TI:8090 None 		     
A0A6I8NHR2_ORNAN
Ensembl»
0.0
ASTE1 Asteroid homolog 1 Ornithorhynchus anatinus
TI:9258 None
   
Q7S890_NEUCR
TubercuList»
0.0
NCU05253 Asteroid domain-containing protein Neurospora crassa
TI:5141 None 		 
 
A7S0X2_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g242074 Asteroid domain-containing protein Nematostella vectensis
TI:45351 None 		 
 
A7T3R9_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g221921 Asteroid domain-containing protein Nematostella vectensis
TI:45351 None 		 
 
A7T769_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g223271 Asteroid domain-containing protein Nematostella vectensis
TI:45351 None 		 
 
A7TB36_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g224732 Uncharacterized protein Nematostella vectensis
TI:45351 None 		 
 
A8DVE8_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g225681 Uncharacterized protein Nematostella vectensis
TI:45351 None 		 
 
ASTE1_MOUSE
Ensembl»
4.6
Aste1 Single-strand DNA endonuclease ASTE1 (EC
3.1.-.-) (Protein asteroid homolog 1)		 Mus musculus
TI:10090 None
 
F7E008_MONDO
Ensembl»
0.0
ASTE1 Asteroid homolog 1 Monodelphis domestica
TI:13616 None
   
F7DBN4_MACMU
Ensembl»
0.0
ASTE1 Asteroid homolog 1 Macaca mulatta
TI:9544 None
   
W5M077_LEPOC
Ensembl»
0.0
Asteroid homolog 1 Lepisosteus oculatus
TI:7918 None 		 
 
B7P5X2_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW000775 XPG N-terminal domain-containing protein Ixodes scapularis
TI:6945 None
 
ASTE1_HUMAN
Ensembl»
3.2
ASTE1 Single-strand DNA endonuclease ASTE1 (EC
3.1.-.-) (Protein asteroid homolog 1)		 Homo sapiens
TI:9606 None
 
T1EHY5_HELRO
EnsemblMetazoa»
0.0
20196185 Asteroid domain-containing protein Helobdella robusta
TI:6412 None 		 
 
A0A2I2YZV4_GORGO
Ensembl»
0.0
ASTE1 XPG N-terminal domain-containing protein Gorilla gorilla
TI:9593 None
 
A0A644F3D5_GIAIC
TubercuList»
0.0
GL50803_0061105 XPG N-terminal domain-containing protein Giardia intestinalis
TI:5741 None 		 
 
A0A8V0Z097_CHICK
Ensembl»
0.0
ASTE1 Asteroid homolog 1 Gallus gallus
TI:9031 None
   
A0ABI7ZHF3_FELCA
Ensembl»
0.0
ASTE1 XPG N-terminal domain-containing protein Felis catus
TI:9685 None
   
F7BFK5_HORSE
Ensembl»
0.0
ASTE1 Asteroid homolog 1 Equus caballus
TI:9796 None
   
C8V3R5_EMENI
TubercuList»
0.0
ANIA_08292 Asteroid domain-containing protein Emericella nidulans
TI:162425 None 		 
 
ASTE_DROME
FlyBase»
4.0
ast Protein asteroid Drosophila melanogaster
TI:7227 None
 
E9H293_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_324622 Uncharacterized protein Daphnia pulex
TI:6669 None 		 
 
ASTE1_DANRE
ZFIN»
1.0
aste1a Single-strand DNA endonuclease ASTE1 (EC
3.1.-.-) (Protein asteroid homolog 1)		 Danio rerio
TI:7955 None
 
E7F2I2_DANRE
ZFIN»
0.0
aste1b Asteroid homolog 1b
(Single-strand DNA endonuclease ASTE1)		 Danio rerio
TI:7955 None
 
Q5KAE5_CRYD1
TubercuList»
0.0
CNJ01980 Asteroid domain-containing protein Cryptococcus deneoformans
TI:40410 None 		 
 
F6PSV0_CIOIN
Ensembl»
0.0
XPG N-terminal domain-containing protein Ciona intestinalis
TI:7719 None
 
F6RYX9_CIOIN
Ensembl»
0.0
Uncharacterized protein Ciona intestinalis
TI:7719 None 		 
 
F6ZMB7_CIOIN
Ensembl»
0.0
Asteroid domain-containing protein Ciona intestinalis
TI:7719 None 		     
F7BDQ8_CIOIN
Ensembl»
0.0
XPG N-terminal domain-containing protein Ciona intestinalis
TI:7719 None
 
A0A8I3PXB1_CANLF
Ensembl»
0.0
ASTE1 Asteroid homolog 1 Canis lupus
TI:9612 None
   
A0A9J7LAD2_BRAFL
euHCVdb»
0.0
LOC118417641 Protein asteroid homolog 1-like Branchiostoma floridae
TI:7739 None 		     
A0A3Q1LUG8_BOVIN
Ensembl»
0.0
ASTE1 Asteroid homolog 1 Bos taurus
TI:9913 None
   
A0A1S4H2G4_ANOGA
EnsemblMetazoa»
0.0
XPG N-terminal domain-containing protein Anopheles gambiae
TI:7165 None
 
G1K9T1_ANOCA
Ensembl»
0.0
ASTE1 Asteroid homolog 1 Anolis carolinensis
TI:28377 None