Collated Gene Ontology terms

Biological process: methylated histone binding(2009, 2010, 2022, 2024) chromatin binding(2017, 2022, 2024) single-stranded RNA binding(2011, 2024) ubiquitin-protein transferase activator activity(2014, 2024) sequence-specific DNA binding(2019) hydrolase activity(2024) DNA binding(2019)

Molecular function: negative regulation of transcription by RNA polymerase II2011, 2022, 2024 heterochromatin formation2000, 2021, 2023 chromatin organization2024 positive regulation of collagen biosynthetic process2014, 2024 positive regulation of cell population proliferation2014, 2024 positive regulation of DNA repair2014, 2024 cellular response to hydrogen peroxide2014, 2024 wound healing2019 ventral cord development2015 syncytial blastoderm mitotic cell cycle2007
specification of segmental identity, abdomen2006 regulation of transcription by RNA polymerase II2021 regulation of DNA-templated transcription2007 neuron remodeling2007 neurogenesis2008 negative regulation of response to gamma radiation2013 negative regulation of gene expression2018 negative regulation of DNA-templated transcription2012 hematopoietic progenitor cell differentiation2017 anterior/posterior axis specification2021

Cellular component: PRC1 complex2006, 2011, 2023, 2024 chromatin2008, 2011, 2022, 2024 nucleus2000, 2011, 2024 PcG protein complex2011, 2024 nucleoplasm2013, 2023, 2024 heterochromatin2011, 2024 chromosome2024 nuclear body2023, 2024 membrane2024 polytene chromosome band2019
polytene chromosome2020 nucleolus2013

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 5 10 15 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
PC_DROME
FlyBase»
16.1
Pc Polycomb group protein Pc (Protein polycomb) Drosophila melanogaster
TI:7227 None
 
A0A8I5ZMG5_RAT
RGD»
6.7
Cbx8 Chromobox 8 Rattus norvegicus
TI:10116 None
   
CBX8_HUMAN
Ensembl»
3.1
CBX8 Chromobox protein homolog 8 (Polycomb
3 homolog) (Pc3) (hPc3) (Rectachrome 1)		 Homo sapiens
TI:9606 None
 
CBX8_MOUSE
Ensembl»
2.1
Cbx8 Chromobox protein homolog 8
(Polycomb 3 homolog) (Pc3) (mPc3)		 Mus musculus
TI:10090 None
 
CBX6_HUMAN
Ensembl»
2.3
CBX6 Chromobox protein homolog 6 Homo sapiens
TI:9606 None
 
A0A287BL41_PIG
Ensembl»
0.0
CBX8 Chromobox 8 Sus scrofa
TI:9823 None
   
A0A3Q1MCA3_BOVIN
Ensembl»
0.0
CBX8 Chromobox 8 Bos taurus
TI:9913 None
   
A0A5F8AKL3_MACMU
Ensembl»
0.0
CBX8 Chromobox 8 Macaca mulatta
TI:9544 None
   
G3QPR3_GORGO
Ensembl»
0.0
CBX8 Chromobox 8 Gorilla gorilla
TI:9593 None
 
H2QE06_PANTR
Ensembl»
0.0
CBX8 Chromobox 8 Pan troglodytes
TI:9598 None
 
A0A1D5QQQ4_MACMU
Ensembl»
0.0
CBX6 Chromobox 6 Macaca mulatta
TI:9544 None
   
A0A286ZRM0_PIG
Ensembl»
0.0
CBX6 Chromobox 6 Sus scrofa
TI:9823 None
   
A0A5F5XK72_FELCA
Ensembl»
0.0
CBX6 Chromobox 6 Felis catus
TI:9685 None
 
K7CGH5_PANTR
Ensembl»
0.0
CBX6 Chromobox 6 (Chromobox homolog 6) Pan troglodytes
TI:9598 None
 
CBX6_MOUSE
Ensembl»
0.8
Cbx6 Chromobox protein homolog 6 Mus musculus
TI:10090 None
 
A0A2I2Y460_GORGO
Ensembl»
0.0
CBX6 Chromobox 6 Gorilla gorilla
TI:9593 None
 
A0A8I3NRL5_CANLF
Ensembl»
0.0
CBX8 Chromobox 8 Canis lupus
TI:9612 None
   
E9PT11_RAT
RGD»
2.5
Cbx6 Chromobox 6 Rattus norvegicus
TI:10116 None
   
F7A2M6_HORSE
Ensembl»
0.0
CBX8 Chromobox 8 Equus caballus
TI:9796 None
   
A0A0E4G888_ANOGA
EnsemblMetazoa»
0.0
Chromo domain-containing protein Anopheles gambiae
TI:7165 None
 
B7QCX4_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW012843 Nucleolin, putative (EC
3.4.21.72) (Nucleolin, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
D6X112_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_12316 Polycomb Tribolium castaneum
TI:7070 None
 
Q502N4_DANRE
ZFIN»
2.3
zgc:111978 Chromobox homolog 8b
(Zgc:111978) (Zgc:111978 protein)		 Danio rerio
TI:7955 None
 
A0A1L8GGZ8_XENLA
Xenbase»
0.0
cbx6.S Chromobox protein homolog 6 Xenopus laevis
TI:8355 None
   
A0A3B3H947_ORYLA
Ensembl»
0.0
cbx8 Chromobox 8 Oryzias latipes
TI:8090 None
   
A0JMJ7_DANRE
ZFIN»
1.5
cbx8 Chromobox homolog 8 (Pc class
homolog, Drosophila) (Chromobox homolog 8a)		 Danio rerio
TI:7955 None
 
A3KMW6_BOVIN
Ensembl»
0.0
CBX6 CBX6 protein (Chromobox 6) Bos taurus
TI:9913 None
 
F7AX29_MONDO
Ensembl»
0.0
Chromo domain-containing protein Monodelphis domestica
TI:13616 None
   
H2LYR7_ORYLA
Ensembl»
0.0
LOC101160413 Chromobox protein homolog 8 Oryzias latipes
TI:8090 None
   
Q5M982_XENLA
Xenbase»
0.0
cbx8.S Chromobox 8 S homeolog (LOC496172 protein) Xenopus laevis
TI:8355 None
 
Q63ZN4_XENLA
Xenbase»
0.0
cbx6.L Chromobox 6 L homeolog (LOC494770 protein) Xenopus laevis
TI:8355 None
 
Q6NTQ8_XENLA
CTD»
0.0
MGC83092 MGC83092 protein
(Uncharacterized protein LOC414709)		 Xenopus laevis
TI:8355 None
 
W5N8W9_LEPOC
Ensembl»
0.0
Chromobox 8 Lepisosteus oculatus
TI:7918 None
 
A0A3B3H2X9_ORYLA
Ensembl»
0.0
Chromobox homolog 6a Oryzias latipes
TI:8090 None
   
A0A6I8NQP6_ORNAN
Ensembl»
0.0
CBX8 Chromobox 8 Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7GFE9_STRPU
EnsemblMetazoa»
0.0
Chromo domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7GLJ5_STRPU
EnsemblMetazoa»
0.0
Chromo domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7NRU4_STRPU
EnsemblMetazoa»
0.0
Chromo domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7NWG1_STRPU
EnsemblMetazoa»
0.0
Uncharacterized protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A8M9PRX0_DANRE
ZFIN»
1.5
cbx6a Chromobox protein homolog 6 isoform X1 Danio rerio
TI:7955 None
   
A7RJQ9_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g238789 Chromo domain-containing protein Nematostella vectensis
TI:45351 None
 
A7S7R4_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g243415 Chromo domain-containing protein Nematostella vectensis
TI:45351 None
 
A7USE0_ANOGA
EnsemblMetazoa»
0.0
5667629 AGAP003793-PA Anopheles gambiae
TI:7165 None
   
T1FVM0_HELRO
EnsemblMetazoa»
0.0
20212866 Chromo domain-containing protein Helobdella robusta
TI:6412 None
 
E9FXE5_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_191862 Chromo domain-containing protein Daphnia pulex
TI:6669 None
 
A0A2K3E4X4_CHLRE
EnsemblPlants»
0.0
CHLRE_01g002203v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A7M7SYC5_STRPU
EnsemblMetazoa»
0.0
Chromo domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3PP91_CANLF
Ensembl»
0.0
CBX6 Chromobox 6 Canis lupus
TI:9612 None
   
A0A8V0YA29_CHICK
Ensembl»
0.0
CBX6 Chromo domain-containing protein Gallus gallus
TI:9031 None
   
Q0IIR6_XENTR
Xenbase»
0.0
cbx8 Chromobox 8 (Chromobox homolog
8) (Chromobox protein homolog 8)		 Xenopus tropicalis
TI:8364 None
 
Q28IA4_XENTR
Xenbase»
0.0
cbx6 Chromobox 6 (Chromobox homolog
6) (Chromobox protein homolog 6)		 Xenopus tropicalis
TI:8364 None
 
A0A803T7X1_ANOCA
Ensembl»
0.0
cbx8 Chromobox 8 Anolis carolinensis
TI:28377 None 		     
A0A8V1AIW2_CHICK
Ensembl»
0.0
CBX8 Chromobox 8 Gallus gallus
TI:9031 None 		     
A0A9J7M4D5_BRAFL
CTD»
0.0
LOC118428434 Chromobox protein homolog 8-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7M6F9_BRAFL
CTD»
0.0
LOC118428437 Chromobox protein homolog 2-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7M6G7_BRAFL
CTD»
0.0
LOC118428448 Chromobox protein homolog 7-like Branchiostoma floridae
TI:7739 None 		     
A7TA22_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g151943 Chromo domain-containing protein Nematostella vectensis
TI:45351 None 		 
 
B3SDQ8_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_62418 Chromo domain-containing protein Trichoplax adhaerens
TI:10228 None 		 
 
M3WY12_FELCA
Ensembl»
0.0
CBX8 Chromobox 8 Felis catus
TI:9685 None